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870-900 / 1000+ resultscommunity Would Fluridil and Alfatradiol work effectively in conjunction with each other?
Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.
community 1 year of .5mg oral dut, .3% topical fin and 6% topical min everyday
A 25-year-old is experiencing hair thinning despite using 0.5mg oral dutasteride, 0.3% topical finasteride, and 6% topical minoxidil daily for a year. They are considering increasing dutasteride dosage and exploring other treatments like microneedling and KX 826, while seeking further medical opinions on their condition.
community Using Fin and Alfatradiol in conjunction?
User considers adding Alfatradiol to their topical finasteride treatment for hair loss. Others discuss Alfatradiol as a weak estrogen and 5α-reductase inhibitor used for pattern hair loss in men and women.
community I want to attempt to use the MPC inhibitor JXL-069
The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.
community Alfatradiol and Fluridil enough? Thoughs on topical fin?
The user is currently using alfatradiol and fluridil for hair loss and is considering adding low-dose topical finasteride but is concerned about potential side effects due to past mental health issues. They are seeking others' experiences with these treatments and their effectiveness.
community Topical Finasteride -- Without Propylene Glycol (PG)
The user seeks alternatives to Propylene Glycol (PG) for delivering topical finasteride due to scalp irritation. They consider using Propanediol 1,3 and ask for other suggestions.
community Microneedling. What is your approach?
The conversation is about using microneedling for hair loss treatment, including questions on disinfection and post-treatment care. The user mentions using oral minoxidil and finasteride, and considering dutasteride.
community Update to fin 0.25 mg, 4x/week
User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.
community Severe Panic Attacks on 1mg Fin: Alternative Options?
The user experienced severe side effects from finasteride, including panic attacks and suicidal thoughts, and is seeking alternative hair loss treatments. They have been using oral finasteride and topical minoxidil.
community Minoxidil 5% with 0.01% tretinoin
Minoxidil 5% combined with 0.01% tretinoin may be as effective as using minoxidil twice daily. Users discuss switching to oral minoxidil for consistency, with concerns about side effects.
community NW7 recovery attempt, a little over 2 month progress. 1.25mg fin, 5mg topical minox twice a day. Pyrilutamide for 1 month, switched to RU58 2 weeks ago, weekly microneedling 1.5mm
A user is attempting to recover from severe hair loss using 1.25mg finasteride, 5mg topical minoxidil twice daily, pyrilutamide for a month, RU58841 for two weeks, and weekly microneedling at 1.5mm. They have seen new hair growth after two months and plan to continue the treatment for a year with the hope of regrowing enough hair for a transplant.
community Need supplemental products in addition to oral minoxidil and oral dutasteride
The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.
community Most reliable place to buy Pyrilutamide that ships to the UK?
The conversation is about finding a reliable source to purchase Pyrilutamide that ships to the UK. There's also an openness to using RU58841 as an alternative.
community [Research/Science] What's the General Consensus On Pyrilutamide So Far?
Pyrilutamide is considered to work for hair loss but less effectively than expected, similar to RU58841, and may cause side effects like chest tightness and sexual issues. It's unclear if it's suitable for diffuse thinners, and one user cannot use minoxidil or finasteride due to side effects and personal circumstances.
community Thinking of crushing bicalutamide/spiro or any other test suppressant in my topical fin min mix. What do yall think?
The conversation is about adding crushed bicalutamide or spironolactone to a topical mix with finasteride and minoxidil to suppress testosterone in hair follicles, similar to what RU58841 does. The user cannot obtain RU58841 in their country and is seeking advice on this alternative approach for hair loss treatment.
community Finasteride stopped working, I'm switching to oral Dutasteride
The user switched from Finasteride to topical Dutasteride, Pyrilutamide, and Minoxidil due to hair loss, then decided to switch to oral Dutasteride because of pregnancy concerns. They are considering the frequency of oral Dutasteride use, with suggestions of using it a few times a week for better results and fewer side effects.
community What are some promising/revolutionizing treatments that are in the pipeline/currently available?
The conversation discusses various hair loss treatments, including pyrilutamide, RU58841, topical dutasteride, oral minoxidil, and oral finasteride/dutasteride. It also mentions potential treatments like PP405, Verteporfin, GT20029, and AMP303.
community Possibilities without Fin/Dut ?
The user experiences severe side effects from finasteride and dutasteride, including low libido and anxiety, and is currently using oral minoxidil despite shortness of breath. They are seeking alternative treatments for hair loss, having tried pyrilutamide, fluridil, and RU58841 with no success, and are considering future treatments or a hair transplant.
community Is Pyrilutamide a failure? I'm just now catching up on the news regarding it for the first time in awhile.
Pyrilutamide appears to be ineffective for hair loss. Users discuss alternatives like Minoxidil, finasteride, and RU58841.
community 27M - look 2 months on Oral 3-in-1 - 1.1mg fin+5g min+ 1mg biotin
A 27-year-old male experienced significant hair regrowth in two months using a daily oral 3-in-1 pill containing 1.1mg finasteride, 5mg minoxidil, and 1mg biotin from LockLab, with no side effects reported. The user also uses a derma-stamp twice a week to promote blood flow and stimulate growth.
community Minox 3mg, Finasteride 1.2mg (6 month perfect adherence)
Significant hair improvement was achieved using 3mg Minoxidil and 1.2mg Finasteride over six months, with no side effects, leading to reconsideration of a hair transplant. A detailed skincare routine, including tretinoin and SPF, also improved skin appearance.
community A topical antiandrogen is very necessary to add to the stack, finastride/Dutastride aren't enough to move the needle.
User added RU and pyrilutamide for hair growth and noticed more baby hairs. Others suggest sticking with fin and min, while some discuss the user's self-image and hair loss severity.
community What’s a better combo: RU + fluridil vs RU + topical spiro vs RU + alfatradiol?
The conversation is about choosing an additional topical treatment for hair loss, with options being fluridil, topical spiro, or alfatradiol, alongside existing treatments like dutasteride, oral minoxidil, latanoprost, and RU58841. Opinions vary on the effectiveness of adding these topicals, with some suggesting RU58841 is sufficient.
community Propylene Glycol vs Glycerin in topical finasterside?
Switching from propylene glycol to glycerin in topical finasteride may reduce systemic absorption and side effects while maintaining local scalp DHT suppression. Concerns exist about glycerin's ability to deliver the full dose to hair follicles.
community please evaluate my potential routine switch
The user is considering switching their hair loss routine from taking finasteride daily to a combination of finasteride six times a week and dutasteride once a week. They are seeking advice on this potential change.
community 5 months oral 1.2mg Fin, 3mg Min. Switching to Dut. 39M
The user has been using oral finasteride and minoxidil for five months with some progress and plans to switch to dutasteride, while also considering a hair transplant for better coverage. Suggestions include adding microneedling, Nizoral shampoo, and possibly using both oral and topical treatments for improved results.
community 27M Seeking Non-DHT Blocker Alternatives After Minoxidil and Finasteride Issues
A user is seeking hair loss treatments without using systemic DHT blockers like finasteride due to side effects. Suggestions include clascoterone (not FDA approved), pyrilutamide, RU58841, and low-dose topical finasteride, with a recommendation to consult a doctor.
community 12 Months 1mg Oral Fin 5mg Min
A 24-year-old user shared their 12-month progress using 1mg oral finasteride and 5mg oral minoxidil for hair loss, reporting significant improvement after initially starting with 2.5mg minoxidil. They experienced no side effects and noted thicker eyelashes, with results becoming noticeable around the 9th or 10th month.
community 3 Months – Fin/Min Micro dosing, micro needling and massaging
User reports hair loss improvement with twice-weekly 0.25mg Fin, twice-weekly Min, weekly 0.5mm microneedling, and daily massages. Unconventional regimen contradicts typical advice but may reduce side effects.