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      community Red Light Therapy: my experience

      in Research/Science  14 upvotes 1 year ago
      A user shared their positive experience with the Omnilux Red Light mask for skin and potential hair benefits, while also using Minoxidil, Dutasteride, and RU58841. They recommend the mask for those interested in skincare and red light therapy, despite being unsure of its effectiveness for hair growth.

      community Vitamins Deficiency and blood works result

      in Treatment  2 upvotes 9 months ago
      The conversation is about a user planning to start minoxidil treatment and considering increasing zinc intake to improve testosterone and libido. They are concerned about potential hair loss due to increased testosterone and are advised to consider magnesium supplementation and the effects of DHT if not on finasteride or dutasteride.

      community Being non responsive on dut and min

      in Is this regrowth?  6 upvotes 2 weeks ago
      The user is experiencing hair loss despite using dutasteride, minoxidil, and ketoconazole shampoo, and is concerned about continued shedding. Suggestions include checking for nutrient deficiencies, consulting a dermatologist, and considering other potential causes like seborrheic dermatitis or telogen effluvium.

      community Binding affinity of pyrilutamide!

      in Update  170 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community One year on finasteride has reversed some aging

      in Chat  198 upvotes 6 months ago
      Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

      community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

      in Research/Science  5 upvotes 9 months ago
      Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  13 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
      27M: Dutasteride and Minoxidil for Eyebrow Thinning and Hair Loss, Seeking Advice

      community 27M: Dutasteride and Minoxidil for Eyebrow Thinning and Hair Loss, Seeking Advice

      in General  183 upvotes 8 months ago
      A 27-year-old male experienced limited success with Dutasteride and topical Minoxidil for hair loss and eyebrow thinning, with side effects like decreased libido and erectile dysfunction. He is considering oral Minoxidil but is concerned about side effects, and is advised to try ketoconazole for possible dermatitis and monitor vitamin D levels.

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 2 years ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community Diffuse thinning chronicles pt. 2

      in Progress Pictures  16 upvotes 1 year ago
      A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.

      community 2,5-3 months progress. I might be a hyper responder?

      in Is this regrowth?  17 upvotes 3 weeks ago
      The user is experiencing reduced hair shedding and increased hair density after using finasteride, minoxidil, derma rolling, granactive retinoid, and Nizoral, while also taking testosterone and aromatase inhibitors. They question if they are a hyper responder to the treatments, despite mixed feedback from others about visible progress.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
      1.5 years topical min and fin where do I go from here

      community 1.5 years topical min and fin where do I go from here

      in General  69 upvotes 1 year ago
      The user has been using topical minoxidil and finasteride for 1.5 years, which has thickened existing hair but left some areas thin. They suspect the treatment may be causing dandruff or seborrheic dermatitis and are seeking advice.

      community Seb derm is eating my hair?!?!

      in Chat  41 upvotes 2 years ago
      A 22-year-old male is experiencing hair loss due to seborrheic dermatitis, not male pattern baldness, and is seeking advice. Suggestions include using Nizoral, sulfate-free and ketoconazole shampoos, cutting hair short, using cold water, avoiding picking scabs, and trying selenium sulfide shampoo or finasteride.
      One-sided diffuse thinning - what should I do?

      community One-sided diffuse thinning - what should I do?

      in General  101 upvotes 4 months ago
      The user is experiencing one-sided diffuse thinning and has been using finasteride and liquid minoxidil for 4-5 years with minimal results. They are considering whether to save for a hair transplant or address scalp sensitivity and irritation first.