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      community Taking part in a Clascoterone Study

      in Treatment  6 upvotes 2 years ago
      The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.

      community Pyrilutamide update number 3 - 1.5 months

      in Update  52 upvotes 3 years ago
      A user's update on their hair loss treatments, which included Minoxidil and finasteride; they are experiencing reduced shedding with minimal side effects. Other users provided additional advice to the poster based on their own experiences.

      community Anyone use stemoxydine here daily?

      in Treatment  1 upvotes 7 months ago
      Stemoxydine is discussed as a hair loss treatment with no reported side effects. The conversation explores its effectiveness and safety.

      community how to consume castor oil? m20

      in Treatment  7 upvotes 5 years ago
      The conversation is about using castor oil for hair loss treatment alongside finasteride and minoxidil. Users discuss the method of consuming castor oil, its potential side effects, and question its effectiveness for hair growth.

      community Need advice whether on starting Fin

      in General  217 upvotes 1 year ago
      The user is considering starting finasteride for hair loss prevention, expressing concerns about potential side effects like reduced libido and erectile dysfunction. They are currently taking saw palmetto, vitamin D, zinc, vitamin C, and biotin but are unsure if these will be effective.

      community What’s the deal with pyrilutamide?

      in Research/Science  53 upvotes 4 years ago
      The effectiveness of pyrilutamide, a hair loss treatment, with research results being postponed until September. Various people shared their experiences with topical finasteride, minoxidil and RU58841, as well as other treatments such as dandruff shampoo, group buys and grey markets.

      community topical minoxidil (5%) & kx826 (.5%) update.

      in Progress Pictures 9 months ago
      The user has been using topical minoxidil (5%) for two years and kx826/pyrilutamide for one year, after experiencing side effects from finasteride. They report positive results from the combination of minoxidil and kx826 in combating hair loss.

      community Minoxidil: Sulfotransferase Enzyme booster AVAILABLE NOW

      in Minoxidil  7 upvotes 2 years ago
      A new product, Minoxidil booster, which enhances sulfotransferase enzyme activity in the scalp, is now available. The user has started using this product, applied before Minoxidil, to improve their hair loss treatment results.

      community Pyrilutamide (has anyone seen improvements)

      in Research/Science  18 upvotes 3 years ago
      Pyrilutamide and its effectiveness for treating hair loss, with advice from other users cautioning to wait at least 6 months before expecting any results. Treatments discussed include finasteride and minoxidil.

      community Making topical finasteride solution

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user has been mixing finasteride with stemoxydine for hair loss and is considering switching to a less expensive product with a different ingredient list. They are questioning if the new product's higher water content compared to alcohol will affect the finasteride's solubility.

      community How much caffeine to add to home solution

      in Research/Science  5 upvotes 2 years ago
      A user is creating a home topical solution for hair loss using zinc, essential oils, and caffeine, aiming for a 0.001% caffeine concentration. They also use topical finasteride and are considering other treatments like low-level laser therapy, while discussing the effectiveness of various hair loss treatments with others.

      community Finasteride and hormonal tests

      in Finasteride/Dutasteride 5 months ago
      A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

      community Best vehicle for topical melatonin?

      in Treatment  5 upvotes 4 years ago
      The conversation is about creating a homemade solution for hair loss treatment, specifically asking for advice on what base to use for topical melatonin. No specific treatments were discussed.

      community 11 month progress on oral min/fin

      in Progress Pictures  424 upvotes 1 year ago
      The user experienced significant hair regrowth using a daily capsule containing 1mg finasteride, 2.5mg minoxidil, and 10mg biotin, with noticeable results after 3-4 months. They reported a decrease in libido as a side effect and considered switching to minoxidil only, but were advised against it.

      community Homemade fin - solubilization issue

      in Treatment  1 upvotes 3 years ago
      The user is attempting to create a topical finasteride solution by mixing crushed finasteride pills with minoxidil but is facing solubility issues. They are unsure if the finasteride has dissolved properly and are seeking advice on whether it is safe to use and if there is a solution to the problem.

      community My experience with 1mg fin eod

      in Finasteride/Dutasteride  19 upvotes 3 years ago
      A 30-year-old man shared his experience with finasteride, taking 1mg every other day, which led to sexual side effects and other issues, prompting him to stop the treatment despite initial hair improvement. He previously tried natural methods and minoxidil without much success and is now considering a buzzcut.

      community Vasodilators, Min, L-arginine, Niacin, Lisinoprol, etc.

      in Minoxidil  4 upvotes 3 years ago
      The conversation discusses the use of vasodilators like Minoxidil, L-arginine, and Niacin for hair regrowth, with Minoxidil causing intolerable side effects for the original poster. It also highlights that certain medications, including Lisinopril, antidepressants, and statins, can cause hair loss.

      community Anyone with LPP have regrowth with Xeljanz?

      in Treatment  3 upvotes 1 year ago
      The conversation is about using Xeljanz for hair regrowth in individuals with LPP. The user is seeking experiences and expectations from others who have tried this treatment.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.