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      community Binding affinity of pyrilutamide!

      in Update  170 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Request for advice, feedback...

      in Chat  2 upvotes 10 months ago
      The conversation discusses hair loss treatments for a woman experiencing androgenetic alopecia and seborrheic dermatitis, with suggestions including low-dose oral minoxidil, dutasteride, and hormone replacement therapy. The user is seeking advice due to intolerance to spironolactone and topical minoxidil, and concerns about low testosterone and DHT levels.

      community 21 months on topical minoxidil and full HRT

      in Transgender  214 upvotes 1 year ago
      The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  75 upvotes 9 months ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  27 upvotes 3 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community Combining daily microneedling and redlight is a game changer

      in Microneedling  22 upvotes 1 year ago
      The conversation discusses using daily microneedling at 0.25mm and red light therapy to enhance hair regrowth, especially when traditional treatments like finasteride and minoxidil become less effective. The combination is said to improve hair density and thickness, with red light therapy being more cosmetic, while microneedling is essential for challenging areas.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 4 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community My progress story for my hair loss treatment

      in Progress Pictures  400 upvotes 2 years ago
      User's hair loss treatment progress includes 1 mg finasteride, 2.5 mg minoxidil tablets twice daily, microneedling 3 times a week, and Fungoral shampoo twice weekly. Good progress and minimal side effects reported.

      community Year and a half progress pictures

      in Progress Pictures  13 upvotes 2 years ago
      The post discusses a user's hair loss treatment routine, which includes daily 1mg finasteride, twice daily topical rogaine, biotin vitamin intake, and a new microneedling regimen of 0.5mm three times a week. The user is turning 24 next month.

      community Losing Hope, Not Sure if I should keep fighting

      in Update  4 upvotes 5 years ago
      The user is experiencing severe hair thinning and is using multiple treatments including topical finasteride, minoxidil, tretinoin, latanoprost, oral minoxidil, dutasteride, saw palmetto, and derma wounding. They are considering adding RU58841 and are contemplating a hair transplant and exosomes due to frustration with current results.

      community Today I start with this: RU58841

      in Progress Pictures  31 upvotes 3 years ago
      The conversation is about a person starting treatment with RU58841 for hair loss. They are asked to share progress pictures to show if the treatment is effective.

      community Not responding to any treatment - is HT the only way?

      in Progress Pictures  4 upvotes 3 months ago
      The user has tried various treatments for hair loss, including finasteride, dutasteride, and oral minoxidil, but is considering a hair transplant due to insufficient progress. Some users suggest that the treatments have at least stabilized hair loss, and recommend consulting clinics for a potential hair transplant while continuing medication.

      community Am I throwing too much at my hair ?

      in Treatment  5 upvotes 3 years ago
      User has been using minoxidil for 5 years and recently started finasteride, 2% nizoral shampoo, low light level laser helmet, microneedling, and biotin supplement to prepare for a hair transplant. Another user suggests it's not too much and mentions additional treatments like dutasteride, oral min, RU, and pyrilutamide.

      community [2 months progress] 1mg oral fin + 2.5mg oral min daily

      in Progress Pictures  7 upvotes 1 week ago
      The user reported tiny hair growth in thinning areas and improved thickness after 56 days of using 1 mg oral finasteride, 2.5 mg oral minoxidil, and a serum with Redensyl, Anagain, Capixyl, and Procapil. They also take supplements and maintain a healthy lifestyle with no noticeable side effects.
      I need advice on my status quo, further actions and diagnostic

      community I need advice on my status quo, further actions and diagnostic

      in General  163 upvotes 10 months ago
      The user is experiencing hair loss, possibly due to androgenic alopecia or telogen effluvium, and is considering treatments like Minoxidil, Finasteride, or RU58841. They also mention potential iron deficiency and sleep deprivation as contributing factors.

      community 9 months progress. Started treatment in Aug 24

      in Progress Pictures  227 upvotes 11 months ago
      The user shared progress pictures showing hair growth after 9 months of using 1 mg oral finasteride, 2.5 mg oral minoxidil (recently increased to 5 mg), and 2% ketoconazole shampoo. Users discussed the effectiveness and side effects of these treatments, with some suggesting alternative methods and cautioning about minoxidil dosage.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community Bloodwork after 8 months on finasteride, is this normal?

      in Update  27 upvotes 1 year ago
      A user on finasteride for 8 months shared bloodwork results showing increased testosterone and estradiol levels, with concerns about high LH. Responses advised monitoring for symptoms but noted levels are within reference ranges.

      community progress pics (HRT, fin, min, microneedling) (35, trans non-binary)

      in Transgender  11 upvotes 1 year ago
      A non-binary transfeminine person experienced significant hair regrowth after starting finasteride, minoxidil, microneedling, and hormone replacement therapy with estradiol. They encourage trans individuals concerned about hair loss to consider estrogen as it has greatly improved their hair condition.

      community Latanoprost- an effective medication

      in Treatment  6 upvotes 2 months ago
      Latanoprost is discussed as a potential hair loss treatment, noted for its synergy with minoxidil and 5-AR inhibitors, but concerns include its effectiveness on scalp hair, cost, and potential skin darkening. Some users express interest in trying latanoprost or bimatoprost despite limited real-world evidence.