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Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

Minoxidil (Lipogaine) and Ketoconazole shampoo (Regenepure) are recommended for hair loss treatment, while finasteride is considered risky due to potential side effects. Biotin is not advised due to possible health risks, and the user emphasizes the emotional impact of hair loss and the hope for a future cure.

The user plans to switch from topical to oral finasteride (1mg/day) and minoxidil (3mg/day) due to unsatisfactory results with topical treatments. They seek advice on the effectiveness, potential side effects, and the timing for considering a hair transplant, with recommendations to monitor health metrics like blood pressure and conduct thorough bloodwork before starting.

The user experienced significant hair loss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.

The user is experiencing hair loss with symptoms of receding hairline, extreme shedding, and low density, possibly due to androgenic alopecia, diffuse thinning, retrograde alopecia, or telogen effluvium. They have used minoxidil and noticed changes in shedding patterns related to different water qualities and seborrheic dermatitis.

A 24-year-old is struggling with severe depression and anxiety due to hair loss, despite using dutasteride and oral minoxidil for two years. They are advised to consider shaving their head, exploring wigs or hair systems, and focusing on other aspects of life like health, relationships, and career.

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

A 31-year-old man using finasteride for a year is considering adding oral minoxidil or switching to topical minoxidil to address diffuse thinning, while also using a scalp massager and ketoconazole shampoo. Concerns include cardiovascular side effects, pet safety with topical minoxidil, and cost of telehealth services.

A 30-year-old female shares her positive progress with hair regrowth using topical minoxidil and vitamins, after experiencing hair loss since her early 20s. She mentions using a product with a natural DHT blocker and emphasizes the importance of checking vitamin and iron levels.

A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

Some individuals experience hair loss despite using treatments like 2.5 mg dutasteride, finasteride, and minoxidil, suggesting sensitivity to DHT or other factors. Various treatments and lifestyle changes are discussed, but results vary, and some consider hair transplants or other solutions.

A physician experienced hair thickening and new growth using microneedling and minoxidil, but stopped using topical finasteride due to side effects like reduced libido and erectile dysfunction. The physician plans to continue with microneedling and minoxidil, considering finasteride nonessential for cosmetic purposes.

DHT is essential for androgenetic alopecia, not testosterone. Treatments like finasteride and dutasteride reduce DHT, halting hair loss.

A 15-year-old is experiencing hair loss and has tried rosemary and jojoba oils without success. They are advised to see a doctor for thyroid and androgen tests and consider using Minoxidil.

The user has been on finasteride for 7 years and had a hair transplant, but is experiencing hair thinning and itchiness, particularly on one side, leading to concerns about male pattern baldness or other health issues. Despite having a full head of hair, the user is considering shaving it due to mental health struggles and is advised to consult a therapist and consider other treatments like minoxidil or dutasteride.

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

A 31-year-old male is using a hair loss treatment routine that includes daily 0.5mg dutasteride, 5% minoxidil, microneedling, biotin, vitamin D, omega-3 supplements, and alternating shampoos to restore hair density. He reports no side effects or noticeable regrowth yet but feels optimistic about the process.

User shared 4-month progress on hair loss treatment using 0.25mg finasteride daily and topical minoxidil daily, noting cognitive decline possibly linked to finasteride. Users discussed side effects, alternative treatments, and shared similar experiences.

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

A 19-year-old is using hair tonic capsules, Minoxidil 5% lotion, an unidentified hair lotion, and Nizoral shampoo for male pattern hair loss. Commenters suggest focusing on known treatments like Minoxidil and Finasteride and advise knowing the contents of the products used.

A 19-year-old user shared impressive hair growth results after using 5% topical minoxidil foam and 1mg finasteride for two months, along with vitamin D. They recommend this regimen for others, noting significant improvements in hair thickness and health.

Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.

A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hair loss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.

The conclusion of the conversation is that the user regrets not starting finasteride earlier to treat their hair loss. They are currently using dutasteride, oral minoxidil, and RU58841. Other users in the conversation express frustration with fearmongering about finasteride and emphasize the benefits of starting treatment early.

After suffering from hair loss and trying various treatments like finasteride, minoxidil, RU58841, and scalp micropigmentation without lasting success, the individual found freedom and a renewed sense of self by shaving their head and accepting their baldness. They encourage others struggling with hair loss to not waste years searching for a cure and to consider embracing a shaved head as a positive solution.

The user "ajsr8" shared their story of hair loss despite being on treatments. They started using finasteride in 2019 and later tried topical minoxidil, but it didn't seem to work. They also experienced side effects from other treatments. They are considering cutting off their hair and stopping the medications if there is no improvement in three months. Other users suggested trying different treatments and getting a blood test to check for underlying conditions.

User took vitamin D for 6 months and experienced hair regrowth. Others suggest comparing hair at the same length and lighting for accurate results.

A user reporting an extended shedding period of 9 months while using finasteride and minoxidil, and other users offering advice on treatments such as dutasteride, multivitamin, biotin, rosemary oil, Kiel's magic elixir, hair extensions, changing hair color, healing crystals, and seeing a dermatologist.