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      10 Months on Minoxidil + Finasteride, No Thickening in Frontal Region

      community 10 Months on Minoxidil + Finasteride, No Thickening in Frontal Region

      in General  91 upvotes 5 months ago
      The user has been using a topical solution containing minoxidil and finasteride for 10 months but is not satisfied with the results, as there is no significant hair regrowth or thickening. They are questioning whether they are a non-responder or if they should continue the treatment longer.

      community Reasonable and safe stack? Bloodwork within.

      in Minoxidil  1 upvotes 2 years ago
      A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

      community RU58841 and some major questions?

      in Treatment  6 upvotes 2 years ago
      A user is asking about the effectiveness and dosage of RU58841 for hair loss, comparing it to Minoxidil and discussing its long-term use alongside Finasteride. They plan to use RU58841 and Finasteride for several years before potentially switching to GT20029.

      community Pictures that demonstrate Minoxidil aging?

      in Minoxidil  7 upvotes 3 years ago
      The conversation is about the potential aging effects of oral minoxidil on the skin. Users discuss their experiences, with some attributing skin changes to aging rather than minoxidil, and mention using tretinoin to improve skin appearance.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community 1.5 years on oral 0.5 mg dut and 2.5mg minox

      in Is this regrowth?  8 upvotes 1 month ago
      A 23-year-old male has been using oral dutasteride and minoxidil for 1.5 years for temple recession, adding topical minoxidil and tretinoin 5-6 months ago, and recently adjusted thyroid medication and added iron supplements due to deficiencies. He noticed some baby hairs but no significant growth yet, and reports no shedding on dutasteride.

      community Took a month break from oral minox, wondering the logistics

      in Minoxidil  1 upvotes 2 months ago
      A 20-year-old stopped oral minoxidil (3mg) for a month due to health concerns and lack of significant results, while continuing topical minoxidil (7%) with tretinoin and finasteride (1mg). They experienced placebo side effects and are considering resuming oral minoxidil, seeking advice on potential setbacks.

      community My Near-Nuclear Stack is Saving me; Hyperresponder?

      in Progress Pictures 1 year ago
      An 18-year-old is using a high-dose hair loss treatment regimen including finasteride, minoxidil, dutasteride, and plans to add RU58841 and bimatoprost, despite warnings from others about the risks. The user is determined to reverse hair loss but acknowledges the potential dangers and does not recommend others follow their approach.

      community Oral minoxidil timeframe (any late responders)

      in Minoxidil  34 upvotes 6 months ago
      Oral minoxidil, finasteride, and dutasteride are being used to treat hair loss, but results are limited, leading to consideration of a hair transplant. The user plans to continue medication for another year before deciding on further action.

      community Anyone with LPP have regrowth with Xeljanz?

      in Treatment  3 upvotes 1 year ago
      The conversation is about using Xeljanz for hair regrowth in individuals with LPP. The user is seeking experiences and expectations from others who have tried this treatment.

      community Curious about 'nuclear' stacks

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.

      community Oral minoxidil or topical with tretinoin?

      in Minoxidil  6 upvotes 1 year ago
      The conversation discusses the effectiveness of oral minoxidil versus topical minoxidil with tretinoin for hair regrowth, with some users suggesting oral minoxidil might be more effective for non-responders to topical treatments. Concerns about side effects and the role of enzymes in activating minoxidil are also mentioned.

      community Any other non-responders to most medications?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The user has not seen results from various hair loss treatments including finasteride, dutasteride, minoxidil, and others over several years and is considering adding RU58841 and starting hormone replacement therapy. They are also experiencing anxiety and contemplating moving to a more accepting environment for their nonbinary identity.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community What is next for pp405 in phase 2b?

      in Research/Science  16 upvotes 1 year ago
      PP405 is progressing to Phase 2b trials, with results expected in late 2025 or early 2026, and potential Phase 3 trials in 2026. Some users experienced side effects from finasteride and are hopeful for PP405 as an alternative treatment.

      community RU58841 mixing with water solution

      in Research/Science  5 upvotes 4 years ago
      RU58841 is being mixed with Minoxidil solution, but concerns arise about water causing instability. Mixing with water may lead to hydrolysis, potentially reducing effectiveness.

      community Combine minoxidil, tazarotene, lumigan

      in Treatment  3 upvotes 10 months ago
      Combining minoxidil 5%, tazarotene 0.1% cream, and lumigan for hair loss treatment is discussed. The conversation focuses on the safety and effectiveness of using these treatments together.