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      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 1 month ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community My Theory Of Androgenic Alopecia

      in Research/Science  20 upvotes 6 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A man in his 80s with full head of hair.

      in Chat  467 upvotes 1 month ago
      Genetics play a major role in hair loss, with some people keeping a full head of hair into old age without using treatments like minoxidil or finasteride. Many express frustration over their own hair loss and the perceived unfairness of genetic differences.

      community Day 0 - 33 - 31M min 5%, Dut 0.5mg/daily, + more

      in Progress Pictures  5 upvotes 1 year ago
      A 31-year-old male is using a hair loss treatment routine that includes daily 0.5mg dutasteride, 5% minoxidil, microneedling, biotin, vitamin D, omega-3 supplements, and alternating shampoos to restore hair density. He reports no side effects or noticeable regrowth yet but feels optimistic about the process.

      community So depressed and upset with how much progress I’ve lost

      in Chat  51 upvotes 2 years ago
      A 20-year-old started taking finasteride for hair loss at 18, saw improvement, but developed erectile dysfunction (ED) after taking accutane. Despite stopping both medications, ED persisted, and hair loss worsened. Advice given includes considering tadalafil for ED, resuming finasteride, using minoxidil, and addressing psychological factors through positive thinking and lifestyle changes.

      community How many of you have significant others?

      in Shaved/buzzed  105 upvotes 2 years ago
      The conversation revolves around the experiences of different individuals with hair loss treatments like Minoxidil, Finasteride, and RU58841. The discussion includes various perspectives on the effects of these treatments, the importance of hair for self-esteem and attractiveness, and the influence of significant others on the decision to use or stop using these treatments.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community Redensyl Megathread !!!!

       42 upvotes 6 years ago
      Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

      community Male pattern baldness is not cosmetic.

      in Chat  223 upvotes 6 months ago
      Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 11 months ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

      community This sub after taking Finasteride for one day

      in Satire  912 upvotes 1 year ago
      The conversation humorously discusses the side effects of finasteride, particularly sexual dysfunction. Users share mixed experiences, with some reporting issues and others not.

      community It is what it is with some people

      in Satire  162 upvotes 5 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with concerns about side effects such as depression and brain fog. Some users argue about the necessity and impact of DHT on libido and other bodily functions.

      community How is dht not beneficial to you?

      in Finasteride/Dutasteride  111 upvotes 4 months ago
      DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

      community CHECKLIST: Blood and other test before starting treatment

      in Treatment  4 upvotes 1 year ago
      Before starting hair loss treatment, it's suggested to undergo various blood and health tests to minimize side effects. The checklist includes tests for kidney function, liver enzymes, blood sugar, vitamins, hormones, and more.
      Deciding Between Oral or Topical Min and Fin with Fatty Liver

      community Deciding Between Oral or Topical Min and Fin with Fatty Liver

      in Basic Questions  77 upvotes 1 week ago
      The user is experiencing hair loss and is considering using topical minoxidil and finasteride due to concerns about liver health, specifically elevated ALT levels from fatty liver. They are advised to start with topical treatments while continuing weight loss and dietary changes to improve liver function.

      community Minoxidil (5% Rogaine foam) 0.5 Dutasteride

      in Minoxidil  15 upvotes 6 months ago
      A user shared their hair loss experience and treatment routine, which includes using Minoxidil (5% Rogaine foam) and Dutasteride 0.5, along with various supplements and natural oils. They reported positive results and emphasized the importance of liver health and thyroid function, despite skepticism from others about the effectiveness of supplements.

      community Why would anyone use Finasteride?

      in Finasteride/Dutasteride 1 year ago
      The conversation discusses hair loss treatments, with a focus on the use of finasteride, minoxidil, laser treatment helmets, and Redensyl. Opinions vary on the effectiveness and side effects of finasteride, with some users advocating for its use despite potential risks, while others express concerns about its impact on sexual function.

      community Can anyone confidently say their erections are the same on fin ?

      in Chat  240 upvotes 2 years ago
      The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.