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      community 2026 Hairloss Nuclear Stack Update

      in Finasteride/Dutasteride  80 upvotes 4 months ago
      A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.

      community Any treatment not nuking systemic DHT levels?

      in Finasteride/Dutasteride  16 upvotes 5 months ago
      Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 6 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community SOS – The cure for women = PREGNANCY

      in Treatment  2 upvotes 6 months ago
      Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.

      community Im at the airport right now and have to apply minoxidil

      in Chat  78 upvotes 6 months ago
      A person was concerned about applying minoxidil and tretinoin in a public airport bathroom, fearing judgment from others. Most responses reassured them that no one cares, suggesting they apply it in a stall or skip a dose without worry.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 6 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Are fruit seeds more effective than fin/Dut?

      in Finasteride/Dutasteride 6 months ago
      The user experienced reduced hair loss after switching from finasteride and dutasteride to consuming fruit seeds like pumpkin and flaxseed, but others suggest the improvement is likely due to the delayed effects of the medications. There is skepticism about the seeds' effectiveness in blocking DHT compared to the medications.

      community 5 months into 0.5mg Dutasteride 3x a week + 5mg Oral Minoxidil

      in Progress Pictures  58 upvotes 6 months ago
      A user is treating hair loss with 0.5mg Dutasteride three times a week, 5mg oral Minoxidil daily, and topical finasteride and minoxidil, seeing some improvement but insufficient density. They are considering increasing Dutasteride dosage and addressing high estradiol levels, while also trying to quit vaping.

      community Minoxidil: Is 2x any better than 1x daily?

      in Minoxidil  8 upvotes 6 months ago
      Using minoxidil twice daily may offer around 20% better regrowth compared to once daily, but once daily is still effective, especially with dermastamping. The user also uses dutasteride and finasteride daily, and is considering increasing minoxidil application despite concerns about cost and potential shedding.

      community Thoughts about ORAL ketoconazole? (pills)

      in Ketoconazole 6 months ago
      Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  4 upvotes 6 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Over a year of only topical minoxidil/ Starting new treatment.

      in Progress Pictures  97 upvotes 6 months ago
      The conversation is about a user who initially had success with topical minoxidil and derma rolling for hair loss but experienced hair loss after stopping. They are now using a new treatment plan including topical and oral minoxidil, finasteride, and ketoconazole shampoo, and are seeking advice on dosage frequency for finasteride.

      community 3 Months on Dutasteride and Minoxidil!

      in Is this regrowth?  25 upvotes 6 months ago
      The user has been using Dutasteride, Minoxidil, and Biotin for three months and believes there is some hair regrowth, especially at the crown, with no significant side effects. Other users suggest that while some thickening and minor growth are visible, more time is needed for full results.
      What should I do 18M facing extreme hair thining and dandruff

      community What should I do 18M facing extreme hair thining and dandruff

      in General  161 upvotes 7 months ago
      An 18-year-old is experiencing severe hair loss and dandruff, feeling stressed and unable to commit to Minoxidil or handle finasteride side effects. They have tried natural oils, anti-hair fall shampoo, and consulted a dermatologist without success, and are seeking affordable treatment options.

      community Progress and results of 3 months of Fin+ Min

      in Progress Pictures  662 upvotes 7 months ago
      A user shared their 3-month progress using topical Minoxidil 5% and oral Finasteride 1mg daily, along with ketoconazole shampoo and derma stamping, reporting significant hair growth without side effects. Some users doubted the results, while others discussed potential side effects of Finasteride and alternative treatments.

      community Those who have taken dutasteride what was your experience?

      in Finasteride/Dutasteride  32 upvotes 7 months ago
      Dutasteride is often preferred over finasteride for hair loss due to its stronger DHT blocking, leading to better hair regrowth for some users. However, it can cause side effects like brain fog, libido changes, and mood issues, prompting some to switch back to finasteride or adjust their dosage.
      What should I start with? Advices are welcomed

      community What should I start with? Advices are welcomed

      in General  189 upvotes 7 months ago
      A 35-year-old is seeking advice on hair loss treatments, considering minoxidil, finasteride, and possibly a hair transplant in Turkey. They have previously tried microneedling for a year.

      community 2 Months 1mg Finasterid daily and Minoxidil 5% twice a day

      in Progress Pictures  286 upvotes 7 months ago
      A 20-year-old male using 1mg finasteride daily and 5% minoxidil twice a day for two months reported significant hair regrowth with no side effects. Users discussed the effectiveness of these treatments, the importance of consulting a doctor, and the potential for continued improvement over time.

      community Finally. Some tangible results. 9mos difference.

      in Progress Pictures  190 upvotes 8 months ago
      The user experienced significant hair improvement over nine months using a routine of oral finasteride, mixed topical and oral minoxidil, microneedling, and Head & Shoulders shampoo. The user attributes the progress to oral minoxidil and reduced stress during paternity leave.

      community Huge anxiety after taking finasteride

      in Treatment  25 upvotes 8 months ago
      The user experiences severe anxiety and physical symptoms after taking finasteride and is seeking alternative hair loss treatments since dutasteride is unavailable. They suspect an allergic reaction to finasteride and have stopped using it.

      community Dutasteride 2.5 mg Progress (3 months)

      in Finasteride/Dutasteride  263 upvotes 8 months ago
      The user reported significant improvement in hair thickness and color in the crown area after 3 months on Dutasteride 2.5 mg and oral Minoxidil 5 mg, with temporary side effects that resolved. They switched from Finasteride to Dutasteride due to lack of results with the former.

      community Oral minoxidil timeframe (any late responders)

      in Minoxidil  34 upvotes 8 months ago
      Oral minoxidil, finasteride, and dutasteride are being used to treat hair loss, but results are limited, leading to consideration of a hair transplant. The user plans to continue medication for another year before deciding on further action.
      Thinning in Hairline and Vertex - What do I do?

      community Thinning in Hairline and Vertex - What do I do?

      in General  345 upvotes 8 months ago
      A 25-year-old male is experiencing hair thinning at the hairline and vertex, considering using a dermapen or dermastamp, and seeking advice on whether to continue with natural remedies like onion juice and rosemary oil or start using minoxidil or finasteride. He is also looking for recommendations on microneedling devices.

      community Male pattern baldness is not cosmetic.

      in Chat  223 upvotes 8 months ago
      Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

      community 5 months Finasteride (.5mg) and Minoxidil (2.5mg)

      in Progress Pictures  223 upvotes 8 months ago
      The user experienced significant hair regrowth and improved hair health after 5 months of using 0.5mg finasteride and 2.5mg minoxidil daily, with only minor side effects like reduced libido. The user is optimistic about achieving over 90% regrowth and may not need a hair transplant.

      community Before & After - 5 months on 0.5mg

      in Progress Pictures  195 upvotes 8 months ago
      The user experienced significant hair regrowth after 5 months on 0.5mg of finasteride, with no side effects except mild, temporary testicular pain. Minoxidil was used for 5 years without noticeable results, and dermastamping and rosemary oil were also mentioned as part of other users' routines.