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      community Why I Take 5mg Minoxidil at Night Instead of Splitting 2.5mg

      in Minoxidil  8 upvotes 1 month ago
      Taking 5mg oral minoxidil at night instead of splitting 2.5mg doses, with the rationale that a single larger dose may provide a stronger activation for hair follicles and reduce peak-related side effects. Some users report sleep issues with nighttime dosing, while others find it beneficial; opinions on effectiveness and side effects vary.

      community Diagnosed with a mild form of Alopecia

      in Treatment 6 years ago
      A user experienced rapid hair loss and was prescribed Desonide cream for mild Alopecia. They are seeking feedback on its effectiveness and potential side effects.
      37 days on dut 0.5mg at 17 progress

      community 37 days on dut 0.5mg at 17 progress

      in General  23 upvotes 1 year ago
      A user shared progress photos after 37 days of using 0.5mg dutasteride for hair loss at age 17. The discussion focuses on the effectiveness of this treatment.

      community RU58841 or topical spironolactone??

      in Research/Science  4 upvotes 4 years ago
      The conversation is about choosing between RU58841 and topical spironolactone for hair loss treatment. The user is currently using a topical solution with minoxidil, alfatradiol, and progesterone, and is concerned about side effects and effectiveness of both RU58841 and spironolactone.

      community My experience with Pyrilutamide

      in Update  3 upvotes 2 years ago
      The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  4 upvotes 1 year ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

      community stemoxydine - how much to actually use?

      in Treatment  3 upvotes 1 year ago
      The conversation discusses using stemoxydine for hair loss, with OP considering using 1.5 ml daily despite the recommended 6 ml. Some users doubt its effectiveness, while others report positive experiences using similar amounts.

      community Can we all agree that PP405 is now 4 years away

      in Chat  95 upvotes 10 months ago
      PP405 is expected to be available in 2028, with ongoing discussions about its timeline and potential effectiveness. Current treatments mentioned include sublingual Minoxidil and Vederamicd, with some users experiencing side effects from oral Minoxidil.

      community Has anyone tried this Ru58841 from Amazon ?

      in Product  3 upvotes 10 months ago
      RU58841 from Amazon is unreliable, with users reporting no benefits and side effects like eye swelling and chest pain. Rudirect is recommended for purchasing in Europe.

      community AA and Hirsutism but T levels are normal

      in Female  5 upvotes 5 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Can I cut back on my Minoxidil dose?

      in Minoxidil  1 upvotes 1 year ago
      OP is experiencing severe side effects from daily Minoxidil, Dutasteride, and Biotin use and is considering reducing Minoxidil to once or twice a week. A response advised seeing a doctor due to heart-related issues.

      community Brutal... RU58841 , is that true ?

      in Update  162 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Concerns are raised about the lack of studies on RU58841 and its potential effects.

      community 11mth daily 0.5mg oral finasteride

      in Finasteride/Dutasteride  835 upvotes 1 year ago
      The user experienced significant hair regrowth with 0.5mg oral finasteride daily, despite a minoxidil allergy, and reported no side effects. They also used a keto shampoo and were satisfied with the results.

      community Dut only? Had to drop oral minoxidil

      in Treatment  2 upvotes 1 year ago
      The user stopped oral minoxidil due to side effects and is now using dutasteride mesotherapy and plans to start oral dutasteride. They are concerned about potential hair shedding and wonder if dutasteride alone will be effective.

      community 5mg KX 826 Worked. Will 2.5mg Hold?

      in Technology  6 upvotes 1 year ago
      Reducing the dose of Pyrilutamide from 5mg to 2.5mg may still maintain hair loss results, but effectiveness can vary. Users discuss the cost and dosage implications, with some cautioning against reducing the dose due to its dose-dependent nature.

      community I mixed ru58841 with minoxidil, help

      in Treatment  4 upvotes 1 year ago
      OP mixed RU58841 with minoxidil and noticed undissolved particles. They are seeking advice on whether it matters or how to fully dissolve it.

      community Quitting Alfatradiol after 4 months

      in Product  5 upvotes 1 year ago
      The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

      community How effective is spironolactone?

      in Transgender  4 upvotes 3 years ago
      A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

      community Dutasteride actually has different half lives depending on dose

      in Research/Science  37 upvotes 1 year ago
      Dutasteride's half-life varies with dosage, and lower doses can be effective with fewer side effects compared to finasteride. Some users report different side effects with dutasteride and finasteride, and extreme dosages of dutasteride are unnecessary and potentially harmful.

      community When do we hear about Pelage February 2025 study results?

      in Technology  14 upvotes 1 year ago
      The conversation is about the anticipated results of Pelage's Phase 2a clinical trial for their topical hair loss treatment, PP405. Users speculate on when the results will be available, noting that delays might indicate less successful outcomes.

      community What oral minoxidil dosage works for you all?

      in Treatment  9 upvotes 2 months ago
      A user is considering using 2.5mg oral minoxidil for hair loss, having already seen some results with 5% topical minoxidil and 1mg finasteride. Others suggest starting with a lower dose to monitor tolerance and adjust as needed.

      community 6 months on 3mg Dutasteride update

      in Chat  6 upvotes 1 month ago
      After 10 months on a high dose of Dutasteride, there were no noticeable benefits or side effects, leading to the conclusion that increasing the dose is overrated. Combining 0.5mg Dutasteride with RU58841 or Minoxidil is recommended for better results.

      community cb-03-01 research chem (winlevi/clascoterone cream)

      in Technology  3 upvotes 2 years ago
      The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

      community Progress with low-dose topicals

      in Research/Science  4 upvotes 2 months ago
      The conversation discusses using low-dose topical finasteride, specifically 0.005% and 0.01%, for hair regrowth, with some users considering increasing the concentration for better results. Users share experiences with different dosages and combinations, including minoxidil, and discuss the effectiveness and availability of these treatments.