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      community Can I take bicalutamide for hair loss as a man, but don’t want to transition?

      in Treatment  3 upvotes 4 weeks ago
      A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.

      community Tressless Pyrilutamide data analytics – Frustrated with lack of data, so I did something about it!

      in Treatment 3 years ago
      This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.

      community Attacking DHT synergistically both locally at the scalp and systemically = Greater Success??

      in Finasteride/Dutasteride  15 upvotes 10 months ago
      The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.

      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Post op day 1, My 10 year journey and thoughts about hair loss, advice

      in Transplants  6 upvotes 4 months ago
      The user shared their 10-year hair loss journey, discussing treatments like oral minoxidil, oral finasteride, and LLLT, and ultimately deciding on a hair transplant. They also explored the possibility of having alopecia areata incognita and advised seeking multiple opinions before surgery.

      community My current regimen for MPB

       4 upvotes 8 years ago
      The user is treating hair loss with dermarolling, a laser helmet, scalp massages, and Nizoral. They stopped using minoxidil and finasteride and are considering pumpkin seed oil and sulforaphane.

      community AA and Hirsutism but T levels are normal

      in Female  4 upvotes 5 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Quitting Alfatradiol after 4 months

      in Product  4 upvotes 1 year ago
      The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

      community Effect of melatonin on aromatase expression

      in Update  4 upvotes 3 years ago
      Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

      community Exosomes for mpb day 1-? Let’s see if it’s bs.

      in Progress Pictures  3 upvotes 3 years ago
      Trying out a new exosome treatment for male pattern baldness, in addition to increasing vitamin intake and using existing treatments such as Nizoral and scalp drops. The user has no expectations that the new treatment will work but is giving it a try anyway.

      community Progress with 7 months of treatment

      in Progress Pictures  82 upvotes 6 months ago
      The user shared progress after 7 months of hair loss treatment using topical minoxidil with finasteride, oral minoxidil, microneedling, LLLT laser cap, and scalp massage. They reported thicker, denser hair with no significant side effects.

      community my mom’s results with exosomes

      in Progress Pictures  23 upvotes 2 months ago
      Exosomes were used for hair loss treatment, showing results 33 days after the second session. The conversation also mentions Minoxidil, finasteride, and RU58841 as treatments.

      community Tropoelastin injections + verteporfin?

      in Research/Science  12 upvotes 3 years ago
      The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

      community Jxl069 (pp405 api) week 8 update

      in Progress Pictures  200 upvotes 8 months ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community 6 month post-transplant, Dr Carman MD surgeon

      in Progress Pictures  5 upvotes 2 years ago
      A user shared their positive experience with a hair transplant performed by Dr. Timothy Carman, using 1100 grafts via FUT surgery, and reported satisfaction with the results and minimal scarring. The user continues to use minoxidil and finasteride for hair maintenance.

      community When you spill minoxidil on your leg

      in Satire  154 upvotes 2 months ago
      Minoxidil can cause hair growth in unintended areas, leading to humorous situations. The conversation jokes about hair growing on legs instead of the head.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Treatments to maintain alternative to finasteride/dutasteride

      in Treatment  6 upvotes 4 years ago
      A 29-year-old male experiencing hair loss due to TRT is using minoxidil and dermarolling but is hesitant to use finasteride or dutasteride due to potential side effects. He is considering low level laser therapy (LLLT), PRP, ketoconazole shampoo, and oral minoxidil as additional treatments. A reply suggests that without a DHT blocker like finasteride or dutasteride, other treatments may not be effective long-term.

      community Good news for stem cells hair therapies - US federal judge: using patients' stem cells does NOT fall under FDA jurisdiction

      in Research/Science  26 upvotes 3 years ago
      A US federal judge ruled that using patients' stem cells for medical treatments is not under FDA jurisdiction, potentially speeding up development of stem cell-based hair loss therapies. Some users are optimistic about increased research and development, while others express skepticism about the ruling's impact on safety and efficacy standards.
      One-sided diffuse thinning - what should I do?

      community One-sided diffuse thinning - what should I do?

      in General  101 upvotes 4 months ago
      The user is experiencing one-sided diffuse thinning and has been using finasteride and liquid minoxidil for 4-5 years with minimal results. They are considering whether to save for a hair transplant or address scalp sensitivity and irritation first.