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      community Progress after 3 months of treatment

      in Progress Pictures  42 upvotes 1 year ago
      The user experienced significant hair regrowth using oral minoxidil 2mg and oral finasteride 1mg daily for three months, with no side effects except a shedding phase. They feel happier and emphasize the importance of emotional well-being in overall health.

      community 4 month top fin/min - is it shedding or not working?

      in Progress Pictures  36 upvotes 1 year ago
      The user is experiencing significant hair shedding after four months of using topical finasteride and minoxidil, questioning if it's a normal shedding phase or if the treatment isn't working. They are considering switching to oral treatments and have increased their finasteride concentration, while also using keto and caffeine shampoos.

      community 2nd shed Update: Lost everything and still losing like crazy.

      in Update  176 upvotes 1 year ago
      The user experienced significant hair loss after initially successful treatment with minoxidil and finasteride, leading to a second shedding phase. They are considering switching to oral minoxidil for convenience and are advised to continue treatment despite the shedding, as regrowth is expected.

      community been using fake minoxidil for almost 2 years

      in Minoxidil  19 upvotes 1 year ago
      The user discovered they had been using fake minoxidil for almost two years, which stopped working, and switched to finasteride, which slowed hair loss. They recently started using real minoxidil and noticed a shedding phase, indicating it might be effective.

      community 1 year year update (.5 mg Dut, 2.5 mg OM)

      in Progress Pictures  335 upvotes 1 year ago
      A 27-year-old male experienced significant hair regrowth using 0.5 mg Dutasteride and 2.5 mg Oral Minoxidil daily, with minimal side effects. He noticed improvement in hairline and crown after an initial shedding phase, and he did not use Finasteride prior to this treatment.

      community 3 months on dutasteride/minoxidil progress

      in Progress Pictures  510 upvotes 1 year ago
      A user shared their 3-month progress using 0.5mg daily dutasteride and 3mg oral minoxidil for hair loss, reporting significant improvement after an initial shedding phase. The user experienced no side effects and noted that dutasteride might have fewer side effects than finasteride.

      community My summation of PP405 - looks promising

      in Research/Science  206 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Tretinoin every other day? (with daily minoxidil)

      in Minoxidil  1 upvotes 1 year ago
      The user is considering using Tretinoin every other day alongside daily Minoxidil to manage hair loss and is concerned about inconsistent absorption affecting regrowth. They have noticed a significant reduction in shedding but are unsure if it's due to Tretinoin or the end of the Minoxidil/finasteride shedding phase.

      community How long does the RU58841 shed last?

      in Treatment  2 upvotes 2 years ago
      The conversation discusses the duration of hair shedding caused by RU58841. The user is stressed and seeking information on how long the shedding phase lasts.

      community Why is there so many people claiming Dutasteride destroyed their hair?

      in Chat  25 upvotes 2 years ago
      Some people claim Dutasteride worsened their hair loss, causing concern among users. Reasons suggested include initial shedding phases, incorrect attribution to Dutasteride when other factors are involved, genetic variations affecting drug response, and the possibility of non-authentic medication.

      community 1 Year Mark. 1mg Oral Finasteride, 5% Topical Minoxidil 2mL

      in Progress Pictures  196 upvotes 2 years ago
      The user has seen significant hair regrowth after one year using 1mg oral finasteride and 5% topical minoxidil, considering a hair transplant if progress stalls. They experienced an initial shedding phase and temporary erectile dysfunction, but no other side effects.

      community Daily scalp massages lead to more hair loss or not?

      in Treatment  10 upvotes 2 years ago
      The user applies castor oil and uses silicon scalp massagers daily, questioning if the massages cause more hair loss or if the hairs would fall out naturally. They believe the hairs are in the telogen phase and would shed regardless of the massage.

      community Finasteride shed is crazy at 7 months

      in Finasteride/Dutasteride  30 upvotes 2 years ago
      The conclusion of the conversation is that experiencing shedding while using finasteride and minoxidil is a common occurrence, and it is likely a part of the hair growth cycle. Many users have reported regrowth and improvement in their hair density after the shedding phase.

      community Stemoxydine- lifelong use? curious.

      in Treatment  5 upvotes 2 years ago
      The conversation discusses whether stemoxydine needs to be used for life for hair loss treatment. One user suggests that stemoxydine does not require lifelong use and can make hair exit the resting phase faster, but the benefits may be temporary.

      community Update to fin 0.25 mg, 4x/week

      in Progress Pictures  62 upvotes 3 years ago
      User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community All Drugs in Clinical Trials in 2023

      in Research/Science  71 upvotes 3 years ago
      12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 6 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community 1 year and 5 months progress oral fin + topical min

      in Progress Pictures  334 upvotes 1 year ago
      User shared progress on hair regrowth using 1.25 mg finasteride daily, 5% minoxidil, and a 1.5 mm dermaroller twice a week, with no side effects. Users discussed shedding phases, application methods, and the necessity of continuous treatment to maintain results.

      community Almost 1 Year (Official mark in 4 days): Baseline diffuse thinning vs. Current density (Regimen in comments)

      in Progress Pictures  136 upvotes 1 month ago
      After a year of using finasteride, topical minoxidil, Nizoral shampoo, and derma stamping, the user experienced significant hair regrowth and increased hair density, despite an initial shedding phase. The user attributes the success to consistency and patience, noting that derma stamping significantly boosted regrowth speed and quality.

      community Minoxidil + Finasteride Experience before vs after

      in Progress Pictures  157 upvotes 3 months ago
      The user experienced significant hair improvement using finasteride, minoxidil, ketoconazole shampoo, and microneedling over a year, with no side effects. They used topical minoxidil and reported shedding phases, but no current shedding as of March 2026.