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      community Inflammation's surprising role in shrinking hair follicles and AGA

      in Technology  66 upvotes 4 weeks ago
      Inflammation plays a significant role in hair follicle miniaturization and androgenetic alopecia, with treatments like ketoconazole shampoo, minoxidil, and finasteride being used to address it. Users discuss the benefits of anti-inflammatory treatments and peptides like KPV, alongside traditional hair loss treatments, to improve scalp health and hair quality.

      community Making minoxidil + azelaic acid type recipes?

      in Minoxidil  4 upvotes 6 years ago
      The conversation is about making a hair loss treatment combining minoxidil with azelaic acid, retinol, and caffeine, similar to the product Xandrox. The user has tried Xandrox but switched to Kirkland minoxidil for cost reasons and is seeking advice on creating a similar mixture.

      community which is better ; minoxidil with more alcohol or more pg?

      in Minoxidil  4 upvotes 3 years ago
      The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.

      community Stoped minoxidil 5 weeks ago and still bloated

      in Minoxidil  175 upvotes 1 year ago
      The user stopped using minoxidil 5 weeks ago due to facial swelling, which initially subsided but then returned. Despite a healthy lifestyle and normal test results, the user is concerned about the persistent bloating.

      community Thoughts on Pantostin Alfatradiol?

      in Treatment  10 upvotes 4 years ago
      User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.

      community New molecule PP405 vs exercise

      in Research/Science  38 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Balding since 2023, topical fin+keto+min since early 2025

      in General  118 upvotes 1 year ago
      The user is stressed about hair loss and is using a HIMS topical treatment containing finasteride, ketoconazole, minoxidil, and biotin, but is concerned about the oily appearance it causes. They are considering switching to Rogaine (minoxidil) due to budget constraints and side effect concerns with oral finasteride.

      community New Study: PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hair follicle stem cells and stimulate natural hair growth by 20%

      in Research/Science  842 upvotes 9 months ago
      PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hair follicle stem cells and increase hair growth by 20% in eight weeks, unlike minoxidil or finasteride. However, skepticism remains about its effectiveness and availability, with concerns about funding and the timeline for broader access.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 5 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Will be experimenting with peppermint oil and olive oil as a carrier.

       5 upvotes 8 years ago
      Peppermint oil and olive oil are being used to potentially improve hair growth, with some initial observations of stronger, thicker hair. Another user is using a mix of peppermint, coconut, castor, and rosemary oils, noting healthier and softer hair but no significant regrowth yet.

      community Do these two supplements inhibit 5alpha-reductase?

      in Chat  1 upvotes 5 years ago
      Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.

      community Using essential oils as well as minoxidil?

      in Minoxidil  5 upvotes 8 years ago
      The conversation is about using a blend of coconut oil, peppermint oil, and rosemary oil with minoxidil for hair loss, and whether it's safe to apply this blend after microneedling.

      community 24F - AGA & TE since 14. Is this regrowth for sure?

      in Is this regrowth?  2 upvotes 5 months ago
      A 24-year-old woman with AGA and TE since age 14 is questioning if her hair is regrowing or breaking. She has been using minoxidil consistently since September 2025, along with caffeine and ketoconazole shampoos, rosemary oil, and saw palmetto, and has improved her overall hair care routine.

      community New possible minoxidil alternative?

      in Minoxidil  5 upvotes 1 year ago
      A potential alternative to Minoxidil for hair loss is discussed, specifically a sugar hydrogel. Users express skepticism about new treatments becoming reality.

      community Scalp Inflammation is eating my hair!

      in Chat  26 upvotes 2 years ago
      A user with seborrheic dermatitis is experiencing bald spots and hair thinning despite changing their diet and taking oral minoxidil. Another user suggests using ketoconazole shampoo properly, using a scalp massager, applying rosemary/peppermint oil, keeping hair short, and taking fish oil to improve scalp health.

      community oral minoxidil collagen contradiction

      in Minoxidil  13 upvotes 1 year ago
      The conversation discusses concerns about oral minoxidil potentially aging the face by affecting collagen, questioning its systemic effects. The user has successfully used topical minoxidil for years and is hesitant to switch to oral minoxidil.

      community My dermatologist gave me Ell cranell?

      in Treatment  4 upvotes 2 years ago
      The user is seeking advice on a hair loss treatment called Ell Cranell, which contains Alfatradiol. Another user shared information from a study stating that Alfatradiol only slows down or stabilizes hair loss, but does not increase hair density or thickness.

      community ~3 years on fin and alpecin shampoo

      in Progress Pictures  289 upvotes 2 years ago
      The user has been using finasteride and Alpecin shampoo for about three years, reporting thicker hair but an unchanged hairline. They are happy with their hair progress, noting the most improvement in the past five months, and mention a slight decrease in libido.

      community Treating traction alopecia for over a year

      in Progress Pictures  57 upvotes 2 years ago
      The user treated traction alopecia for over a year using Nutrafol, rosemary oil, topical and oral Minoxidil, dermarolling, biotin, collagen, and vitamin D, and shared progress photos to inspire others on their hair growth journey. They also acknowledged the community and a specific person for support and encouragement.

      community 2.5MG Oral Minoxidil, Is This Regrowth?

      in Is this regrowth?  4 upvotes 11 months ago
      The user is using 2.5mg oral Minoxidil, rosemary mint oil, scalp massaging, a derma roller, multivitamins, and hair vitamins for hair regrowth. They are considering adding pumpkin seed oil, a derma pen, and saw palmetto vitamins, and are advised to consider finasteride.

      community Olympia hair growth formula; experience.

      in Product  2 upvotes 2 years ago
      A user shared their experience using the Olympia hair growth formula for a month and asked for others' opinions on its composition. The conversation focuses on the effectiveness of the formula, which includes Minoxidil, finasteride, and RU58841.