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A new hair loss treatment, Pyrilutamide, has been released and is claimed to be a strong anti-androgen, potentially effective when used with finasteride. However, there are mixed opinions on its effectiveness and safety, with some users skeptical and others purchasing it.

Veradermics is working on FDA approval for extended-release oral Minoxidil. Approval is expected around 2027.

The user shared progress pictures after 2.5 years of using oral minoxidil (5mg daily) and finasteride (1mg daily) for hair loss, noting significant improvements over time. They experienced normal shedding and some beard growth, with no negative side effects reported.

The user experienced hair regrowth using 1 mg finasteride and 5% minoxidil for 4 months, then switched to 0.5 mg dutasteride, 1.5 mg minoxidil, microneedling, and ketoconazole shampoo for 8 months. They noticed significant improvement after switching to dutasteride.

A dermatologist prescribed oral minoxidil, finasteride, and spironolactone, suggesting minoxidil and finasteride as the most effective combination, but with potential side effects. Another user recommended minoxidil (both topical and oral) and spironolactone for female hair loss, advising against finasteride.

The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.

A 26-year-old male used 1mg oral finasteride and 5% topical minoxidil for a year, noticing progress despite initial skepticism and minor side effects. He applied minoxidil to both the hairline and entire scalp, and attempted microneedling but discontinued due to sneezing.

Switching from propylene glycol to glycerin in topical finasteride may reduce systemic absorption and side effects while maintaining local scalp DHT suppression. Concerns exist about glycerin's ability to deliver the full dose to hair follicles.

Exploring alternatives to Minoxidil for hair loss, such as Bimatoprost and Latanoprost, as well as potential treatments like Finasteride and RU58841.

A user shared progress on hair regrowth using 5mg oral minoxidil and 0.5mg oral dutasteride daily, noting small hair growth and no significant side effects except bushier eyebrows. The conversation includes encouragement, personal experiences with hair loss treatments, and discussions on the effectiveness of microneedling.

The user reports hair regrowth at the crown and thickening at the front after three months using 1mg finasteride, 0.5% minoxidil, biotin supplements, vitamin D, and argan oil shampoo and conditioner. They express a wish that hair growth could occur at the back of the head as well.

Combining microneedling with Low Level Laser Therapy (LLLT) for hair growth, with discussions on device legitimacy and effectiveness. Alternatives like PEMF and the use of oral and topical treatments such as dutasteride, minoxidil, and finasteride are also considered.

User shared before and after photos of 8 months using Finasteride 1mg and Minoxidil 5% 1ml nightly, with positive results and no side effects. Others praised the progress and suggested alternative treatments like topical fin, CB-03-01, or RU58841.

The user reported progress in hair growth after 4 months using 0.5 mg finasteride and 2.5 mg minoxidil daily, and is considering adding RU58841 to block DHT on the scalp. They experienced side effects like reduced libido and mild erectile dysfunction, and take supplements like zinc, iron, fish oil, vitamin D, magnesium, and vitamin E.

Pyrilutamide, a potential topical treatment for male pattern baldness, and the user's anticipation of its Phase 2 trial results. Several users discussed their experiences with Finasteride and RU58841, while others voiced skepticism about the efficacy of Pyrilutamide.

A user shared their 4-month hair regrowth progress using 0.5mg dutasteride and 2.5mg minoxidil, reporting no side effects and significant improvement. The conversation includes discussions on treatment choices, dosages, and personal experiences with hair loss treatments.

A 35-year-old man shared his progress using oral finasteride and minoxidil for over a year, reporting no significant side effects and improved hair growth. He emphasized the importance of nutrition and plans to continue the treatment indefinitely.

The user started finasteride two weeks ago and has been using minoxidil for over a month, while also supplementing with Acetyl L-Carnitine. They are curious if others have experienced hair shedding or growth with Acetyl L-Carnitine, especially when used with finasteride and minoxidil.

A 25-year-old male experienced noticeable temple regrowth using 1mg finasteride, 2.5mg oral minoxidil, and 2mg GHK-Cu over three months. The user is pleased with the progress, especially on the left temple.

The user experienced significant hair regrowth after six months of using oral Finasteride (1mg) and Minoxidil (2.5mg) nightly, with no side effects. They also used dermastamping and biotin, emphasizing consistency and a healthy lifestyle.

Discussion on hair loss treatments, focusing on pp405, with skepticism about its effectiveness and concerns about its association with the cosmetic industry. Users also mention treatments like Minoxidil and Finasteride.

A 24-year-old male doctor shares his 3-month progress using 0.5 mg oral finasteride and 5% topical minoxidil daily, noting some hair regrowth and incorporating microneedling. He prefers a "less is more" approach initially and discusses the potential benefits of oral minoxidil.

The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

The conversation discusses hair loss treatments, specifically the transition from topical to oral minoxidil and finasteride, and the associated shedding phase. Users advise patience and consistency, noting that shedding is common and improvement may take several months.

The user shared a 10-month hair loss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.

The user started balding at 16/17 and tried various treatments including minoxidil, finasteride, and dutasteride with little success. They recently started applying diclofenac gel to their bald areas and noticed some hair regrowth, attributing this to diclofenac's ability to lower prolactin levels and its anti-inflammatory effects.

The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

A 27-year-old Asian male is treating hair loss with 1mg oral finasteride, topical minoxidil twice daily, and 1.5mm microneedling weekly. The discussion is about his progress with these treatments.

User is using topical Minoxidil (100 mg/day) and Finasteride (1 mg/day) but experiencing hair growth everywhere except the top of the scalp. They seek advice on improving scalp hair regrowth.