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The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

The conversation discusses hair loss treatments, specifically the use of finasteride and minoxidil in a topical compound, along with microneedling. Users share progress and experiences, noting significant hair growth and improvements over time.

Diffuse thinners often experience more hair regrowth with DHT blockers like finasteride, possibly due to less DHT sensitivity and the presence of miniaturized, not completely bald, follicles. However, regrowth varies widely among individuals, influenced by factors like genetics, the stage of hair loss, and treatment methods such as minoxidil, microneedling, and dermarolling.

The user, a 27-year-old male, has been treating early hair loss with topical finasteride and minoxidil, then switched to oral finasteride and dutasteride, but has seen no improvement and plans to add oral minoxidil. Despite treatment, hair loss has progressed from Norwood 1-1.5 to Norwood 3, with noticeable thinning, especially on the left side.

The user reported good progress in hair regrowth, especially on the crown, after using oral minoxidil and finasteride for four months and recently switched to dutasteride. The community responded positively, noting realistic progress and offering tips for consistent photo documentation.

A 31-year-old male shared his 3-year progress using finasteride 1 mg daily, with additional treatments including nutrafol, multivitamins, vitamin D, marine collagen, PRP scalp injections, micro-needling, and Nizoral. He experienced temporary libido issues but currently has no side effects.

A 35-year-old user shared their 4-month progress using Minoxidil, Finasteride, microneedling, and vitamins to treat hair thinning. They reported increased hair density, thicker strands, and deeper color, especially in the crown area.

The user shared progress pictures after 10 months using Dutasteride 0.5 mg (Avodart) and Minoxidil 5% (Kirkland) for hair loss. They also lost weight, improving their appearance and making them look younger.

The user has been using finasteride for over a year and topical minoxidil since March, noticing small hairs but no significant regrowth. Suggestions include continuing the current treatment, considering microneedling, and possibly trying oral minoxidil for better results.

A user shared their 6-month progress using 1ml of Kirkland minoxidil daily and weekly 1mm dermarolling, noting no side effects and minimal shedding. They plan to consider finasteride or dutasteride after midterms, attributing hair loss to genetics.

The user experienced significant hair maintenance using 0.25mg daily finasteride and minoxidil foam, with minimal side effects. They recommend oral finasteride for better results, especially for the crown area.

User shared 9 months of progress using 1 mg finasteride and topical minoxidil, showing photos from different stages. Encouragement was given to continue the treatment.

User considers scalp micropigmentation (SMP) for hair loss. Mixed opinions shared; some regret it, others satisfied. Choosing reputable clinic and technician is important.

A 42-year-old man's two-month hair loss treatment progress using topical finasteride, oral minoxidil, microneedling, and keto shampoo. He noticed improvements, including new hair growth, despite minor side effects like mild ache and increased libido initially.

Longitudinal partial follicular unit transplantation involves extracting part of the donor follicular unit, allowing the donor area to be overharvested without noticeable hair loss. The conversation questions if this method is practiced in clinics or if it's theoretical, and whether it relates to hair cloning or multiplication.

A man, 35, shows 3-month hair regrowth progress using 0.4mg oral finasteride, 1.0mg minoxidil, topical minoxidil once daily, weekly dermastamping at 1.5mm, and ketoconazole shampoo. He experienced initial worsening, has no side effects, and received positive feedback on his early results.

Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.

Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

The conversation discusses whether finasteride and minoxidil can help regrow hair at the corners, with one user suggesting that recovery is possible even from worse conditions.

The user has severe diffuse thinning on the scalp and is using finasteride, topical minoxidil, dermarolling, tretinoin, and Nizoral without satisfactory results. They are considering a hair transplant but are concerned about the cost and the number of grafts needed.

This post by "vicky8201" documents their progress in treating hair loss with Minoxidil and Finasteride, which resulted in a transition from NW4 to NW2.5 over the course of two months. Master_Blaster999 and lovindicks both commented on the results, noting that it is nearly impossible to grow that much hair in such a short time frame.

A 22-year-old male is using topical dutasteride, minoxidil, tretinoin, and microneedling for hair loss, experiencing some side effects like mild ball pain and initial shedding but seeing progress in hair thickness. He plans to increase the dutasteride dose and has tried various treatments, including finasteride and RU58841, with differing side effects.

A man saw improvement in hair loss after a year using 1mg finasteride daily and minoxidil twice daily, but reduced finasteride due to side effects. He switched to 0.5mg dutasteride daily, topical finasteride twice daily, microneedling weekly, and 2.5mg oral minoxidil, but may stop minoxidil due to chest pains.

The user is likely at Norwood level 3 with thinning at the crown and temple recession. Treatments like finasteride or minoxidil are suggested to manage hair loss.

The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

The user reported tiny hair growth in thinning areas and improved thickness after 56 days of using 1 mg oral finasteride, 2.5 mg oral minoxidil, and a serum with Redensyl, Anagain, Capixyl, and Procapil. They also take supplements and maintain a healthy lifestyle with no noticeable side effects.

The conversation discusses a 24-year-old Korean man's progress with hair loss treatments over 8-9 months, with specific treatments not mentioned due to redacted information. Users are commenting on the effectiveness and inquiring if Asians have better results with hair loss treatments.

The conversation is about someone's progress with hair loss treatment using a combination of topical finasteride and minoxidil, and dermastamping once a week. They are considering increasing the dermastamp needle size from 1.25mm to 1.5mm.

Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

The user shared their one-year progress using 5% topical minoxidil and 1mg oral finasteride, reporting good results with some shedding phases. They experienced no side effects and noted improved hair density, especially in the frontal area.