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      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  5 upvotes 3 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Just over a month on min and fin

      in Is this regrowth?  9 upvotes 3 months ago
      The user is experiencing hair regrowth after using 1mg finasteride and 5% minoxidil twice daily, along with weekly dermarolling. They are considering switching to a combination spray due to reduced libido from finasteride.

      community Is this progress? 19M 5%topical min/1,25mg fin

      in Is this regrowth?  7 upvotes 3 months ago
      A 19-year-old is using 5% topical minoxidil, 1.25 mg finasteride, ketoconazole, and a dermaroller for hair regrowth, noticing improvement in the frontal area. Another user suggests adding oral minoxidil and maintaining a consistent routine, emphasizing the importance of stress management and a healthy diet for better results.

      community 24M, 0.5 Dut, 2.5mg Min, 10mg Biotin. 2 month crown update.

      in Progress Pictures  30 upvotes 3 months ago
      A 24-year-old male shares his two-month progress on hair regrowth using 0.5mg Dutasteride, 2.5mg Minoxidil, 10mg Biotin, and Ketoconazole shampoo, noting significant crown improvement. Users discuss the effectiveness of oral Minoxidil, with some expressing skepticism about photo angles and the necessity of Biotin unless deficient.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 3 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community My 8 months hair transplant surgery update.

      in Progress Pictures  9 upvotes 4 months ago
      A user shared an 8-month update on their hair transplant surgery, which used 1800 grafts for aesthetic refinement, resulting in a natural-looking hairline and improved confidence. The procedure was performed by Dr. Abhinav Kumar, and the user is pleased with the results.

      community M22, Finasteride 3 Months in, seeking advice!

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      A 22-year-old male with a family history of baldness has been using finasteride for 3 months and previously used minoxidil. He is concerned about hair loss progression and seeks advice on whether to restart minoxidil and improve his lifestyle, while being advised to be patient with the treatment.

      community Any long term positive experiences with just minoxidil plus a dermaroller?

      in Minoxidil  10 upvotes 4 months ago
      Minoxidil and dermarolling can yield positive hair growth results, but long-term effectiveness varies, and some users experience hair loss again without additional treatments like finasteride. Microneedling enhances minoxidil's effectiveness by increasing enzyme activity, but individual experiences differ.

      community 6 Months (July-December). Fin + Min.

      in Progress Pictures  380 upvotes 4 months ago
      The user experienced significant hair regrowth in six months using 1.25mg oral finasteride and topical Kirkland minoxidil once a day. Others suggested additional treatments like dermastamping and alternative products, while some noted varying responses and potential side effects.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  23 upvotes 5 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community Been on oral min + fin since 2024

      in Is this regrowth?  112 upvotes 5 months ago
      The user experienced significant hair regrowth using oral minoxidil and finasteride, noticing results in about two months and regrowth in four months, with no side effects except an initial shedding. They attribute their success to lifestyle changes like hydration and sleep, and they occasionally use topical minoxidil for their beard.

      community Should I drop topical minoxidil?

      in Minoxidil 5 months ago
      The user is considering stopping topical minoxidil due to health risks and inconvenience, while continuing oral minoxidil, dutasteride, and vitamins. Others suggest that oral minoxidil carries more risk, and results from treatments may take 3-6 months to appear.

      community Don’t do like me. Don’t take a long break from Fin and Min

      in Chat  124 upvotes 6 months ago
      Stopping finasteride and minoxidil can cause significant hair shedding, so they should be continued indefinitely. Concerns about finasteride affecting fertility or causing birth defects are mostly unfounded, but some stop for personal reasons.

      community 25M 4 months Fin + oral Min keep hope

      in Progress Pictures  228 upvotes 6 months ago
      A 25-year-old male shared his hair loss journey, using finasteride and oral minoxidil, which improved his hair density and quality. He also addressed dermatitis with exfoliation and anti-dandruff shampoo, and emphasized the importance of a healthy scalp and lifestyle changes.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

      in Chat  4 upvotes 7 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community Losing hair? Finasteride should be the first step

      in Finasteride/Dutasteride  284 upvotes 7 months ago
      Finasteride is effective for hair loss, with significant results after consistent use, and minimal side effects reported. Users discuss dosage, shedding, and combining treatments, with some considering adding Minoxidil or switching to Dutasteride.

      community mom said my hair looks great and im more handsome than ever

      in Chat  68 upvotes 7 months ago
      The conversation discusses hair loss treatments, specifically using finasteride, dutasteride, and minoxidil. The original poster mentions adding dutasteride to their regimen alongside finasteride, noting thicker hair, while others share experiences and concerns about these treatments.

      community Switching from Finasteride to RU58841?

      in General  168 upvotes 7 months ago
      The user experienced severe side effects from finasteride, including cognitive and sexual issues, despite its effectiveness for hair growth. They are considering switching to RU58841 and seek insights from others who have made a similar change.