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GlossaryMalignancies

abnormal cell growths that invade and spread, causing cancer

Malignancies, also known as malignant tumors or malignant neoplasms, are abnormal growths of cells that have the potential to invade and destroy surrounding tissues and spread to other parts of the body (metastasize). Unlike benign tumors, which are non-cancerous and do not spread, malignancies are cancerous and can be life-threatening if not treated promptly.

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community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Anageninc no longer sell KX-826 (Pyrilutamide) due to receiving a cease and desist letter from Kintor :(

in Update 19 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Anageninc stopped selling KX-826 (Pyrilutamide) due to a cease and desist letter from Kintor, but this may indicate promising study results and a potential 2024 release.

community Prolactin's role in antitumor activity of the immune system - a safety concern for HMI-115?

in Research/Science 4 upvotes 3 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community Female with hair loss - turns out it’s been thyroid cancer

in Update 284 upvotes 2 years ago

A woman with hair loss discovered she has thyroid cancer, which was found during an MRI and confirmed with an ultrasound. She advises others with symptoms to see a doctor and shares that her cancer was detected after her dog sniffed her neck and she experienced neck pain.

community Anyone had a Hair transplant after cancer?

in Hair Transplants 98 upvotes 10 months ago

A blood cancer survivor in remission since 2022 is experiencing thin and patchy hair after chemotherapy and is using Minoxidil without much success. They are seeking personal experiences and advice on hair transplants after cancer treatment.

community 21M with a nasty case of MPB; Heres what's on my radar for the future.

in Research/Science 16 upvotes 3 years ago

Hopeful treatments for hair loss, including Verteporfin, Androgen Receptor Degradation, and SCUBE3. These treatments offer potential solutions to slow or stop the effects of androgens on the scalp.

community Bicalutamide and muscles growth

in Female 8 upvotes 1 year ago

A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

community Anagenic is trying to compound Gt20029

in Treatment 56 upvotes 3 years ago

The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.

14 upvotes 8 years ago

Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.

community can someone help me identify these pls

in Treatment 6 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community China clinics pushing “PT88/PT66 / SP88/SP66 mesotherapy ampoules” + I have seb derm — anyone heard of this / any evidence?

in Research/Science 6 upvotes 5 months ago

The user is exploring hair loss treatments in China, currently using finasteride and minoxidil, and is concerned about seborrheic dermatitis. Clinics are recommending selenium sulfide, doxycycline, and mesotherapy ampoules like PT88/PT66 or SP88/SP66, but the user is unsure about their effectiveness.

community Any concrete cases of people who were told they couldn't have a transplant because of microneedling?

in Hair Systems 26 upvotes 1 year ago

Microneedling before a hair transplant may harden the scalp and affect blood circulation, potentially impacting graft growth. Some users report successful transplants after microneedling, while others advise caution and consulting with a surgeon.

community The case for 5ARI-free hair transplants: Dr. Zarev, Pittella, Sethi, Miln, and future treatments in development

in Treatment 14 upvotes 7 months ago

Some individuals experience side effects from 5AR inhibitors like finasteride and are considering hair transplants without these medications, with some opting for surgeons like Dr. Zarev. Others are exploring alternative treatments and waiting for new medications in development, while some discuss managing side effects through lifestyle changes or additional medications.

community Kintor pyrilutamide presentation?

in Research/Science 12 upvotes 3 years ago

The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

community Counter-update: Cbum's transplant DOESNT look super good now

in Transplants 221 upvotes 1 year ago

Cbum's hair transplant is criticized for looking unnatural and not blending well, with some suggesting better results were expected given his resources. Discussions also cover the effects of steroids and finasteride on hair loss and muscle growth.

community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

in Treatment 13 upvotes 6 years ago

PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

community Pyrilutamide cease and desist from Kintor

in Transplants 12 upvotes 3 years ago

Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

community May have been mis-diagnosed for 10 years, self-investigation into AGA + AA Incognita (Defused Shedding)

in Treatment 1 upvotes 1 year ago

A 27-year-old male with AGA and diffused thinning has been using oral Minoxidil, Finasteride, Vitamin D, B12, Iron, and Ketoconazole shampoo. Despite a hair transplant and improved blood levels, he continues to experience hair loss and suspects a possible misdiagnosis of Alopecia Areata Incognita.

community MCL1 does anyone knows anthying about it

in Research/Science 9 upvotes 1 year ago

MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

community The Hormonal Profile of MPB/AGA

in Research/Science 9 upvotes 5 years ago

Men with early male pattern baldness (MPB) may have hormonal abnormalities similar to those in women with PCOS. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Someone here experience with/or knows stories of cancer-patience regrowing hair?

in Chat 20 upvotes 5 years ago

Hair regrowth after chemotherapy varies; some experience thinner or differently colored hair, while others may see fuller regrowth. Treatments like essential oils, vitamins, and lifestyle changes are discussed, but no specific medications like Minoxidil or Finasteride were used by the original poster.

community Bimatoprost vs Latanoprost for scalp hair growth

in Treatment 1 upvotes 2 months ago

Bimatoprost and latanoprost are being considered for scalp hair growth, with concerns about side effects like skin darkening and fat loss. A user warns about potential chemical burns from latanoprost.

community Another transplant or SMP? (Not balding)

in Transplants 23 upvotes 4 months ago

The user is considering another hair transplant or scalp micropigmentation (SMP) for a congenital bald spot, but previous transplants were less effective due to scar tissue. Suggestions include using hair fibers, changing hairstyles, or doing nothing, as the spot is not very noticeable.

community I can tolerate having MBP, but other than that having Sebderm is just really bad luck.

in Minoxidil 11 upvotes 1 year ago

The conversation discusses managing seborrheic dermatitis (sebderm) and male pattern baldness (MPB) with treatments like finasteride, coal tar shampoo, Nizoral, and oral minoxidil. Users suggest dietary changes, regular shampooing, and using antifungal products to control sebderm before considering minoxidil.

community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

in Treatment 5 upvotes 1 month ago

A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

community DUPA, Non Responders and Connective Tissue Disorders

in Research/Science 9 upvotes 11 months ago

A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

community upcoming treatments that can be beneficial for those who can’t tolerate dht blockers?

in Update 7 upvotes 2 months ago

Upcoming hair loss treatments for those who can't tolerate DHT blockers, focusing on Minoxidil, microneedling, and ketoconazole. Promising treatments include GT20029, PP405, KX-826, and RU58841, though RU58841 may not be safe.

community Is the clinic diagnosis legit to you ?

in Transplants 1 upvotes 1 year ago

The clinic diagnosed the user with NW3 and AGA, noting thinning hair despite using finasteride for 3 years, and suggested PRP and Mesotherapy before considering a transplant. The user questions the necessity of these treatments without confirming retrograde alopecia and its treatability.

community (Serious) Updates and discussion, new treatments in development

in Treatment 7 upvotes 1 year ago

Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

community Updates on the Sulforaphane group?

in Chat 18 upvotes 4 years ago

Hair loss discussion involves experimenting with Sulforaphane from broccoli sprouts and possibly procyanidin b2. People seek updates on progress and if it's worth adding to treatment stack like microneedling.