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      community Are fruit seeds more effective than fin/Dut?

      in Finasteride/Dutasteride 3 months ago
      The user experienced reduced hair loss after switching from finasteride and dutasteride to consuming fruit seeds like pumpkin and flaxseed, but others suggest the improvement is likely due to the delayed effects of the medications. There is skepticism about the seeds' effectiveness in blocking DHT compared to the medications.

      community How do I look? - Hair transplant update.

      in Progress Pictures  36 upvotes 3 months ago
      A user shared their hair transplant update, having received 4,300 grafts and choosing not to use medications like finasteride or minoxidil due to potential side effects and personal reasons. Many commenters expressed concern that without these medications, the user might experience further hair loss, suggesting that preventative treatments are important for maintaining transplant results.

      community What do you guys think about my foundation?

      in Treatment 3 months ago
      The user had a hair transplant and uses oral minoxidil, a red laser therapy helmet, fish oil, collagen, and sardines for hair thinning but avoids finasteride due to side effect concerns. Many suggest these methods may not be effective long-term without a DHT blocker.

      community Chat is this real? Compound called clascoterone

      in Research/Science  583 upvotes 4 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  23 upvotes 4 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community 4 weeks in (dutasteride only).

      in Progress Pictures  76 upvotes 5 months ago
      A user experienced hairline improvement after four weeks on 1.5mg dutasteride but had side effects like reduced libido and sensitive nipples. They plan to switch to finasteride to manage these side effects.

      community waiting for hope DIY pp405 guy that will save us😡😡😔

      in Satire  38 upvotes 5 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community I was very very very very very very very very wrong

      in Ketoconazole  48 upvotes 6 months ago
      Nizoral, a ketoconazole shampoo, can cause scalp dryness and hair shedding if overused. Users discuss alternatives like Selsun Blue, finasteride, and dutasteride for managing hair loss and seborrheic dermatitis.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 6 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 6 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Surprise Hair Loss Breakthrough: A Sugar Gel Sparks Robust Regrowth

      in Research/Science  131 upvotes 6 months ago
      A sugar gel is claimed to spark hair regrowth, but users express skepticism, noting that minoxidil and finasteride remain the most effective treatments. Many users joke about frequent "breakthroughs" that work on rats but not humans, and some mention the potential of PP405 as a future treatment.

      community Experience with only Minoxidil and Nizoral

      in Minoxidil  6 upvotes 7 months ago
      Minoxidil and Nizoral alone are unlikely to stop hair loss effectively, as they do not address the root cause, which is often DHT. Many users suggest incorporating a 5AR inhibitor like finasteride or dutasteride for better results, despite concerns about potential side effects.

      community Stimulate hair growth- without minoxidil

      in Treatment  10 upvotes 7 months ago
      The user is seeking alternatives to Minoxidil for hair growth, currently using 0.1% topical finasteride and 2% ketoconazole shampoo. Suggestions include microneedling, red light therapy, rosemary oil, and other topical treatments like cetirizine, Stemoxydine, and Latanoprost.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 7 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community Do it yourself topical Fin and Min solution works

      in Progress Pictures  119 upvotes 8 months ago
      A homemade topical solution of finasteride and minoxidil effectively stopped hair shedding and promoted regrowth without side effects. Users shared experiences and discussed different concentrations and application methods.

      community Why so much hate for PP405 all of a sudden?

      in Technology  48 upvotes 8 months ago
      PP405 is a new hair loss treatment facing mixed reactions due to initial hype and insufficient data. Some are hopeful, but many doubt its effectiveness compared to minoxidil and finasteride.

      community What I hate about being told to shave my head

      in Chat  258 upvotes 9 months ago
      Hair loss challenges and identity issues, with opinions on using finasteride, minoxidil, and hair transplants versus accepting baldness. Some find shaving more work, while others stress personal choice and self-perception.

      community [22m] Is it time for a transplant?

      in Progress Pictures  56 upvotes 9 months ago
      A 22-year-old is experiencing aggressive hair loss despite using minoxidil and finasteride and is considering a hair transplant but lacks funds. The discussion includes advice on treatments like dutasteride, microneedling, and lifestyle changes, with mixed opinions on the timing and effectiveness of a transplant at a young age.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 9 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  332 upvotes 10 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community Hormone tests to decide on oral fin

      in Finasteride/Dutasteride  4 upvotes 10 months ago
      The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.