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      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 3 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community Minoxidil and fin ED since November (4-5 months) 21M

      in Progress Pictures 3 years ago
      If you didn't tell them. This conversation is about a user's progress with hair loss treatments using Minoxidil and Finasteride since November of the previous year, which have been successful so far. The other users were making jokes about ED referring to Erectile Dysfunction.

      community Dutasteride .5mg Results Timeline

      in Finasteride/Dutasteride  14 upvotes 2 years ago
      A 21-year-old male switched from finasteride to 0.5mg dutasteride daily due to ongoing hair loss but has not seen improvement after 14 months, experiencing further thinning and recession. He is seeking feedback from other dutasteride users on their results after a similar duration.

      community Finasteride 1 mg,4 months progress result

      in Finasteride/Dutasteride  270 upvotes 2 months ago
      A user experienced positive hair growth results using 5% topical minoxidil for a year and 1 mg finasteride for four months but is considering stopping finasteride due to persistent side effects like libido loss. Others in the conversation discuss similar experiences, suggest trying topical finasteride to reduce side effects, and emphasize the importance of overall health and lifestyle.

      community 6 months in: Possible changes to treatment plan

      in Treatment  1 upvotes 1 year ago
      A 21-year-old male has been on a hair loss treatment for 6 months using finasteride, oral minoxidil, and ketoconazole shampoo, with slight improvement noted by his dermatologist. He is considering adding topical spironolactone, switching to dutasteride, increasing minoxidil dosage, or trying PRP injections for better results.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community 6 months topical liquid min & oral fin

      in Progress Pictures  11 upvotes 1 year ago
      The user completed 6 months of using topical liquid minoxidil and oral finasteride, experiencing initial hair shedding followed by gradual regrowth after 2 months. They also dealt with dandruff and reported no negative impact on sex drive.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Something that helped my Fin sides massively (ED).

       6 upvotes 12 years ago
      Taking 1000mg l-arginine alongside 0.5 mg finasteride every other day helped alleviate erectile dysfunction and possibly increased libido. The user recommends trying l-arginine for those experiencing sexual side effects from finasteride.

      community Progressive insomnia (treatment-resistant) due to Finasteride

      in Finasteride/Dutasteride  8 upvotes 4 years ago
      A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.

      community Steps before starting medication

      in Treatments  336 upvotes 5 months ago
      A 31-year-old man, between Norwood 4 and 5, is considering hair loss treatments like finasteride and minoxidil but is concerned about side effects. He is exploring options with doctors and considering a hair transplant, noting that some clinics require medication before and after the procedure.

      community Figuring out my own experimental protocol

      in Treatment  11 upvotes 3 years ago
      User tries dermapen for hair loss and plans to use non-mainstream topicals like c60, ghk-cu, and ptd-dbm with valproic acid. They also use a head massager and modified LLLT belt for additional treatment.

      community On Dutasteride 0.5mg ED for almost 2 years. Increasingly shedding hair for more than 5 months.

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.

      community Apparently finasteride lowers Free Testosterone?

      in Finasteride  22 upvotes 7 years ago
      Finasteride raises total testosterone but lowers free testosterone, which is important for male health. Users report mixed experiences with their fitness levels and blood test results after using finasteride.

      community 3 month progress (26M) oral fin and oral min

      in Progress Pictures  645 upvotes 1 year ago
      A 26-year-old user shared their 3-month progress using oral finasteride and oral minoxidil for hair loss. They experienced side effects like reduced libido and brain fog at higher doses and adjusted their dosage to manage these effects.

      community Update Fin 2.5 years + min 3 mnts

      in Is this regrowth?  103 upvotes 1 year ago
      User reports using 1.25 mg oral finasteride each morning and 0.75 ml minoxidil topical spray twice a day, along with vitamin D pills. Another user comments on the positive results and asks when finasteride stabilized shedding.

      community Blood test 3 days after finasteride. Is it ok?

      in Finasteride/Dutasteride  3 upvotes 2 years ago
      A user asked if taking a blood test 3 days after starting finasteride would affect the results for Estradiol, FSH, SHBG, Progesterone, and DHEA-S. The conversation is about the timing of blood tests after beginning finasteride treatment.

      community GFC vs PRP with mesotherapy vs exosomes

      in Treatment  2 upvotes 2 years ago
      A 23-year-old male has been experiencing hair loss since 2022 and has used minoxidil and dutasteride with reduced shedding but no hair regrowth. He is considering PRP with mesotherapy and red light therapy, GFC, or exosomes, with a preference for exosomes due to efficiency and a reputable clinic.