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      community How to Add Tretinoin to 2 in 1 combo ?

      in Treatment  2 upvotes 1 year ago
      A user wants to add tretinoin to their nightly minoxidil and finasteride combo to increase effectiveness. They seek advice on how to mix tretinoin with the existing treatment.

      community Dealing with Retrograde Alopecia

      in Treatment  6 upvotes 4 years ago
      User on Dut, oral minox 20 mg, Saw Palmetto, Pumpkin Oil, RU, 8% topical minox, and topical fina for hair loss; top of head improves, but retrograde alopecia worsens. Asks for options besides exosomes and where to find topical melatonin.

      community PRP with Exosomes - The next step for me?

      in Treatment  3 upvotes 2 months ago
      The user is considering PRP with exosomes for hair loss after oral minoxidil and dutasteride failed to provide desired results. Despite suggestions for a hair transplant, the user is hesitant due to cost and complexity, and is unsure about other options.

      community Finasteride alternative close to fda approval in the US

      in Research/Science  57 upvotes 4 weeks ago
      Breezula, a topical treatment, is anticipated to be available in the US by mid-2027 as a potential alternative to finasteride with fewer systemic side effects. There is ongoing debate about its effectiveness and some users report similar side effects to finasteride.

      community TRT. Pyrilutamide. Ru58841. Help

      in Treatment  3 upvotes 2 years ago
      A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.

      community When could we expect pp405 to hit the market?

      in Research/Science  31 upvotes 1 year ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.

      community Hairline update - topical meds

      in Is this regrowth?  53 upvotes 10 months ago
      The conversation is about hair regrowth using topical finasteride, minoxidil, and keto spray, along with oral Saw Palmetto, Lustriva complex, collagen, and microneedling. Users discuss their experiences with these treatments, noting improvements in hair density and color, with some experiencing mild side effects.

      community Questions about using dermapen for microneedling.

      in Microneedling  1 upvotes 1 year ago
      The conversation discusses using a dermapen for microneedling to treat hair loss, with specific mention of using Minoxidil, Finasteride, Dutasteride, RU58841, KX-826, and other topicals. The user experienced side effects like palpitations and itching after microneedling and applying these treatments.

      community Scarring Alopecia and NSAIDs?

      in Female  4 upvotes 5 years ago
      The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 3 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Tazarotene better than Tretinoin with minoxidil?

      in Chat  9 upvotes 1 year ago
      Switching from tretinoin to tazarotene with minoxidil led to new hair regrowth after years of maintenance. Tazarotene's selectivity and higher concentration might be more effective for hair growth.

      community Adding topical Min and dermastamping to oral Min/Fin?

      in Treatment  1 upvotes 4 months ago
      The user has been using oral Minoxidil, Finasteride, and Biotin for hair recovery and is considering adding topical Minoxidil and dermastamping to improve results. It is suggested to use micro-needling once a week with a 24-hour gap before applying topical Minoxidil.

      community Hairloss after doing PRF treatment

      in Treatment  2 upvotes 2 years ago
      The conversation is about the potential risk of permanent hair loss from PRP (platelet rich plasma) treatments and whether PRF (platelet rich fibrin) carries the same risk. The user is seeking information on this topic.

      community Hair shed is driving me crazy/coping with stress

      in Female  11 upvotes 2 years ago
      A 25-year-old female is experiencing hair loss and has tried PRP, Minoxidil 5% with Biotin, and weekly needling sessions. Her doctor suggested switching to GFC treatment and stopping the needling sessions due to increased shedding, which may be caused by Minoxidil.

      community 148 Days Minoxidil+Finasteride Topical, Keto Shampo 2x Weekly

      in Progress Pictures  53 upvotes 3 years ago
      Treating hair loss with a combination of topical minoxidil and finasteride, as well as keto shampoo twice weekly; other treatments such as microneedling and oral finasteride were discussed but the user is hesitant due to potential scarring. Additionally, another user suggested switching to oral minoxidil for further gains.

      community Why can't you drink caffeine after PRP?

      in Treatment  10 upvotes 4 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community 24M seeking help for aggressive androgenetic alopecia - "nuke" stack?

      in Chat  1 upvotes 1 year ago
      A 24-year-old male with aggressive androgenetic alopecia is using 1mg finasteride daily and considering a treatment stack including 0.5mg dutasteride, 2.5mg oral minoxidil, ketoconazole shampoo, Alpecin caffeine shampoo, and RU58841. He seeks advice on the safety and effectiveness of these treatments and whether any adjustments are needed.

      community Updates about KX-826 & GT20029

      in Research/Science  16 upvotes 3 years ago
      The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.