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      community Breezula phase 3 results said to be released next month

      in Product  27 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Got a crazy shred again 3 months after starting daily microneedling

      in Microneedling  2 upvotes 6 months ago
      The user experienced hair loss after switching to daily microneedling and stopping tretinoin, while continuing oral finasteride, minoxidil, and other treatments. The consensus suggests daily microneedling is excessive and harmful, recommending less frequent sessions to allow healing.

      community Kintor’s GT20029 Phase 1 success

      in Update  74 upvotes 3 years ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community Keratin microspheres - breakthrough

      in Research/Science  14 upvotes 2 years ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Fevipiprant 2019!

       15 upvotes 9 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community Progress 1.25years M36 fin/min/ru

      in Progress Pictures  212 upvotes 1 year ago
      A 36-year-old man shared his 1.25-year progress using oral finasteride, oral minoxidil, RU58841, microneedling, nizoral, and LLLT for hair regrowth. He is thrilled with the results and considering a hair transplant for increased density.

      community Ru58841 + Minox progress (1 month

      in Progress Pictures  15 upvotes 2 years ago
      A user shared their one-month progress using Minoxidil and RU58841 for hair loss, noting significant shedding after micro-needling and seeking opinions on their regrowth. They stopped micro-needling and added RU58841 to their treatment.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

      community MinoxiBoost - SULT1A1 Enzyme booster journey

      in Minoxidil  7 upvotes 2 years ago
      The user has tried topical Minoxidil and oral Minoxidil for beard and scalp hair growth with minimal results, and has been on Finasteride for 7 months with stabilized scalp hair but no facial hair improvement. They are considering using a SULT1A1 enzyme booster to enhance results and are questioning its effectiveness without concurrent topical Minoxidil application.

      community Case study: 1mo progress microneedling + minox, no fin.

      in Microneedling  8 upvotes 5 years ago
      A user shared their experience with microneedling and minoxidil for hair loss, avoiding finasteride due to concerns about systemic hormone effects. They reported slight hair regrowth after one month and plan to continue the regimen, noting improvements in skin sensitivity and managing dandruff with anti-dandruff shampoo.
      Help me interpret my bloods

      community Help me interpret my bloods

      in General  65 upvotes 1 year ago
      The user is concerned about high prolactin levels and low testosterone levels after stopping finasteride for three weeks. They are considering resuming finasteride but are worried it might further increase prolactin levels.

      community M28, Surprising 20 day progress

      in Progress Pictures  5 upvotes 2 years ago
      A 28-year-old shared surprising hair regrowth progress after 20 days using topical minoxidil, micro needling, GHK-cu, and BPC-157 injections. The user noted a significant reduction in their bald spot and overall hair improvement.

      community 13 month update - dut, min, niz, 1.5mm roller

      in Progress Pictures  205 upvotes 2 years ago
      The conversation discusses a 13-month hair loss treatment update using dutasteride, minoxidil, nizoral, and a 1.5mm derma roller, with the original poster reporting no side effects and some improvement in hair thickness. Participants request before-and-after pictures with consistent hairstyles to better assess the treatment's effectiveness.

      community 33M 1mg finasteride + topical minoxidil

      in Progress Pictures  59 upvotes 3 months ago
      A 33-year-old man shares his positive hair regrowth results using 1mg finasteride daily, 5% topical minoxidil twice daily, and a 0.5mm dermaroller weekly. He feels more confident and encourages others to try the routine despite potential side effects.

      community 1 Year Progression M18 - Detailed

      in Progress Pictures  30 upvotes 2 weeks ago
      The user experienced significant hair regrowth using finasteride, minoxidil, and microneedling, but saw a decline after reducing treatments and stopping gym workouts. They plan to restart microneedling and consider a hair transplant in the future.

      community 13 months finasterid + 2.5 years Minoxidil

      in Progress Pictures  17 upvotes 1 month ago
      The user has been using finasteride for 13 months and minoxidil for 2.5 years but continues to experience significant hair loss. Suggestions include switching to dutasteride and increasing the oral minoxidil dose to 5mg, while also considering lifestyle changes like diet and stress management.

      community Promising new data on peptide serums (not sponsored)

      in Research/Science  7 upvotes 4 months ago
      Combining Minoxidil with peptide serums like Redensyl, Procapil, and Capixyl is more effective for hair growth than using Minoxidil alone, increasing hair density and thickness. However, some users are skeptical about the effectiveness of peptides, suggesting other ingredients or factors might contribute to the results.

      community Naturally high T (1,100+) causing diffuse thinning while on Dut

      in Chat  22 upvotes 2 months ago
      A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

      community Betamethasone dipropionate 0.05 (sernivo spray)

      in General  76 upvotes 1 year ago
      A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.