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      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Is it effective to make microneedling without minoxidil?

      in Chat  31 upvotes 7 months ago
      Microneedling can be effective for hair growth, but it is more effective when combined with minoxidil. Finasteride or other DHT suppressants are necessary to prevent hair loss due to male pattern baldness.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 9 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Pyrilutamide cease and desist from Kintor

      in Transplants  12 upvotes 3 years ago
      Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Progress on just minox and dermapen

      in Progress Pictures  16 upvotes 1 month ago
      The user shared progress pictures showing significant hair regrowth using Minoxidil and a dermapen, expressing concerns about potential side effects of finasteride due to low testosterone levels. Another user reported increased testosterone and no side effects from finasteride, with improved libido.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  4 upvotes 1 year ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

      community My results in almost 3 month of fin/min/microneedling.

      in Is this regrowth?  129 upvotes 9 months ago
      A 32-year-old is seeing positive hair regrowth after nearly three months using finasteride, oral and liquid minoxidil, and microneedling, and plans to add RU58841. They are considering switching to dutasteride and possibly a hair transplant in the future.

      community June 15th vs. August 18th (Min/Fin/Dermadtamp

      in Progress Pictures  16 upvotes 2 years ago
      The user has been treating hair loss with Minoxidil, Finasteride, Derma stamping, Nizoral shampoo, and hair and nail vitamins for two months, experiencing mood swings from Finasteride that stabilized over time. They are seeking opinions on their progress.

      community 3-month update on the microneedling-only project

      in Microneedling  90 upvotes 3 years ago
      A 3-month update on a microneedling-only project to treat hair loss, which has not had significant results in terms of thicker hair but may have seen some acceleration in hair growth and an increase in vellus hairs. The user plans to continue the journey for 6 months before making any changes, such as adding minoxidil or finasteride.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

      in Treatment  5 upvotes 2 months ago
      A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

      community 12 months of progress (min+ fin)

      in Progress Pictures  97 upvotes 3 years ago
      Hair loss progress after 12 months using minoxidil, finasteride, and microneedling. Goal is to maintain and improve hair until old enough for hair transplant.

      community M43. 9 months on fin+min oral. Hairline regrowing

      in Finasteride/Dutasteride  317 upvotes 5 months ago
      A 43-year-old experienced hairline regrowth after 9 months using finasteride, oral and topical minoxidil, dermarolling, and vitamins. Users discussed the effectiveness and dosage of these treatments, with some expressing concerns about high doses and potential side effects.

      community 7 weeks on 1mg finasteride/1.5mg minoxidil

      in Progress Pictures  10 upvotes 1 year ago
      A 37-year-old male started a hair loss treatment 7 weeks ago using 1mg finasteride, 1.5mg minoxidil, and microneedling, with noticeable coverage improvement except for the right temple. He is considering a hair transplant in the future if needed.

      community Why microneedling can ruin a hair transplant

      in Microneedling  14 upvotes 1 year ago
      Microneedling's effectiveness for hair growth is debated, with some suggesting it enhances minoxidil absorption, but evidence is inconclusive. Concerns exist about its impact on hair transplants, and opinions vary on its use with other treatments like RU58841 and stemoxydine.

      community Minxodil collegen synthesis decrease?

      in Minoxidil  3 upvotes 1 year ago
      Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.