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      community Clascoterone study going on right now

      in Research/Science  355 upvotes 2 years ago
      A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

      community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

      in Research/Science  2 upvotes 2 years ago
      The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 3 months ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community Looking for the new RU58841 source in EU

      in Treatment  6 upvotes 2 years ago
      A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

      community Looking for the new RU58841 source in EU

      in Treatment  5 upvotes 2 years ago
      A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

      community Mesenchymal Stem Cell Therapy (Exosome) Before & After

      in Treatment  2 upvotes 2 years ago
      A user's father experienced hair regrowth and other health improvements after two IV exosome treatments. The user also had four rounds of exosome therapy, noting significant hair regrowth and relief from headaches, but no change in gray hair.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Any updates or news on Gt20029?

      in Chat  7 upvotes 1 year ago
      There are no updates on GT20029, and concerns about its safety and effectiveness remain. The phase III trial has not started, and there are no new studies or data releases.

      community Minoxidilmax vs Morr-F

      in Product  11 upvotes 6 years ago
      The user is considering two hair loss treatments: Minoxidilmax Maxogen-x, which contains Minoxidil, Finasteride, Azelaic Acid, ABN Complex, Retinoic Acid, Fluocinolone, and Caffeine, and Morr-F, which contains only Minoxidil and Finasteride. They are asking for others' experiences with these brands.

      community Starting my Pyrilutamide + ru58841 journey

      in Treatment  11 upvotes 3 years ago
      An individual's journey to treat their severe hair loss condition using the medications Pyrilutamide and RU58841. They will provide regular updates on their progress.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  107 upvotes 2 years ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  11 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community Anyone tried switching from RU to Pyrilutamide (KX-826)

      in Product  7 upvotes 4 months ago
      The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  10 upvotes 10 months ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community About GT20029's Efficacy and Strength

      in Chat  7 upvotes 3 years ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community Ru58841 + topical minoxidil + microneedling succes story

      in Progress Pictures  339 upvotes 1 year ago
      A user shared their successful hair loss treatment using RU58841, topical minoxidil, and microneedling, noting significant improvement over three months. They chose RU58841 over finasteride due to personal preference and reported no side effects, while others discussed their experiences with different treatments and supplements.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community 2ddr thread, I'll try to add to it monthly

      in Research/Science  19 upvotes 1 year ago
      The user is using a hair loss regimen involving 2ddr applied twice daily, tretinoin weekly, and occasionally micro-needling. They report feeling increased scalp thickness and seeing some hair growth progress.

      community Thoughts on my dermatologist only giving me methionine for AGA?

      in Treatment  4 upvotes 4 years ago
      A dermatologist prescribed methionine with vitamins for hair loss, but the user is doubtful and plans to seek finasteride in France. The user is unsure why finasteride or minoxidil wasn't prescribed, suspecting concerns about side effects or strength.