community Starting my journey after noticing thinning in crown and temples (M25)
Hair loss discussion; treatments include 0.5mg finasteride daily and 1.5mm dr pen weekly on scalp. Monthly progress updates planned.
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420-450 / 1000+ resultscommunity When could we expect pp405 to hit the market?
PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.
community Possibility of updates or more information on the pp405
The conversation discusses the potential updates on the pp405 trial for hair loss, with completion expected by December 2025. Participants express skepticism about new treatments, suggesting continued use of finasteride, while others hope for innovative solutions beyond current medications.
community using Minoxidil 5%+Tretinonin+Azelaic acid topical solution for past 2 months. how's the progress?
A user shared progress pictures after using a topical solution containing Minoxidil 5%, Tretinoin, and Azelaic acid for two months. The conversation discusses the effectiveness of this treatment for hair loss.
community cheapest and best low level laser therapy device
The conversation is about finding an affordable and effective low level laser therapy device for hair loss, with a preference for a cap but open to a comb.
community A reminder that Telogen Effluvium could look like MPB; my progress
A 19-year-old male experienced significant hair loss, initially thought to be male pattern baldness (MPB), and used minoxidil and briefly finasteride. After realizing the issue was telogen effluvium (TE), he improved his diet and supplemented with vitamins, which led to substantial hair regrowth.
community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?
The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.
community 5mg KX 826 Worked. Will 2.5mg Hold?
Reducing the dose of Pyrilutamide from 5mg to 2.5mg may still maintain hair loss results, but effectiveness can vary. Users discuss the cost and dosage implications, with some cautioning against reducing the dose due to its dose-dependent nature.
community New company Amplifica gets $11.8 million in financing for development of its hair loss products. Dr. Maksim Plikus and William Rassman are co-founders.
New company Amplifica receives $11.8 million for hair loss product development, co-founded by Dr. Maksim Plikus and William Rassman. Users discuss undisclosed product candidates and application methods.
community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease
Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.
community Dont know what the hell is going on.
The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.
community "Clinical efficacy of microneedle combined with 5% Minoxidil solution and finasteride in the treatment of androgenetic alopecia in males"
Microneedling combined with 5% Minoxidil and finasteride significantly improves hair growth compared to using Minoxidil or Minoxidil with finasteride alone. The combination treatment is safe and effective, but further research is needed due to small sample size and short study duration.
community Anyone know when phase 2 of the American trials for pyrilutamide should be released by
Researching the release of phase 2 trials for pyrilutamide, a potential hair loss treatment, and discussing other treatments such as Minoxidil, Finasteride, and RU58841.
community Other sulfurtransferase activity upregulator other than Tretinoin?
The user does not respond well to minoxidil and is seeking an alternative to Tretinoin to upregulate sulfurtransferase activity for hair loss treatment. No specific alternative treatments were mentioned.
community Clascoterone vs RU58841? What’s more effective?
Clascoterone and RU58841 are compared for effectiveness in treating hair loss. The discussion involves treatments like Minoxidil, finasteride, and RU58841.
community 5 month progress, should i add fin?
A user shared their 5-month hair regrowth progress using 5% topical minoxidil daily, microneedling weekly, and ketoconazole shampoo twice a week. Some suggest adding finasteride to maintain results, while others commend the current regimen's effectiveness.
community Lilly to seek first approval of an autoimmune drug for hair loss
Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.
community Pyrilutamide cleared for phase 3 clinical trial in china
Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. Pyrilutamide cleared for phase 3 clinical trial in China.
community My Vitamin D (25-0H) levels came <4.20 ng/ml (<20 implies deficiency)and B12 came 184 pg/ml (Should be between 211-911). I have a lot of dandruff. The derm has prescribed me with 60k vitamin d tablet once a week and multivitamins for a month. Vitamin deficiency implies TE no? or is it MPB?
The conversation discusses hair loss treatments, focusing on vitamin D and B12 deficiencies, and mentions using finasteride. It also suggests getting a biopsy to differentiate between MPB and other conditions.
community M20 Vitamin D Deficiency and Hair Thinning
A 20-year-old is experiencing hair thinning due to vitamin D deficiency and has completed a vitamin D prescription without seeing improvement. Suggestions include waiting a few months for potential regrowth or considering treatments like minoxidil or finasteride for androgenetic alopecia.
community Any updates on RCH-01?
The conversation is about seeking updates on the hair loss treatment RCH-01, specifically its next phase and any news from Shiseido. The user recalls someone being in contact with a researcher or company representative.
community hyper responder? is it shockloss or is this baseline? | 23M 3500 grafts | 1000 on crown, 1000 midscalp and 1500 hairline
A user shared progress pictures 1.5 months after a hair transplant of 3500 grafts, using oral finasteride, topical finasteride, minoxidil, and vitamins. They are concerned about potential shock loss and the thinning appearance.
community Considering giving a laser comb a shot. Here’s a summary of my research on the subject.
Considering adding Low Level Laser Therapy (LLLT) to a hair loss prevention regimen; discussing the effectiveness of LLLT, and evaluating double-blind random-controlled trials that have been conducted on laser combs.
community Patent for topical resveratrol and melatonin for AGA
The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.
community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells
PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.
community 25M Low Density Hair, Concerned About Increased Scalp Visibility
The user is experiencing excessive hair thinning and is unsure of the cause. They are seeking opinions on treatments like Minoxidil, finasteride, and RU58841.
community Let Me Sell You on NAC
The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.
community Cassiopea announces completion of recruitment of Phase II dose ranging trial of Breezula (CB-03-01) for androgenic alopecia
The conversation discusses the completion of a Phase II trial recruitment for Breezula (CB-03-01), a potential treatment for androgenic alopecia. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.
community 40M, microneedling + LLT + rosemary oil
A 40-year-old male using microneedling, low-level laser therapy (LLT), and rosemary oil for hair regrowth. No finasteride or minoxidil is used.
community 5 years – Fin, Min, Microneedle and then HT
A user's experience of using Fin, Min and Microneedle treatments to help thicken their hair before undergoing a Hair Transplant (HT) procedure. The conversation also includes discussion about the results post-HT, including pictures.