The user experienced worsening hair loss despite using finasteride and dutasteride. They are considering trying minoxidil but are unsure if it will help.
Pyrilutamide from Ligand Chem was used by several individuals to address hair loss, with mixed results and no significant side effects reported. Some users switched to Minoxidil Max for better value, while others noted no hair growth or only a reduction in shedding.
The conversation is about the stability of pyrilutamide in different solutions. The user is asking if a 70/30 ethanol/pg solution with 4% water will degrade pyrilutamide.
Switching from topical to an oral combo pill (1.2 mg finasteride, 3 mg minoxidil, vitamins) improved hair thickness without noticeable side effects. The user appreciates the convenience of a single daily pill over twice-daily topical applications.
A user's progress with treating hair loss by using finasteride (1mg MWF) and minoxidil (5% once daily), occasionally using ketoconazole gel, and dermarolling 1.5mm every two weeks; other users' responses are positive and ask for more information about the treatment regimen.
The user, Salty-Peace-577, shared their 5-month update on using 0.5mg oral finasteride and 2.5mg oral minoxidil for hair loss. They experienced significant hair growth, particularly in their eyebrows, and shared their regimen and tips for hair growth. Some users in the conversation also discussed the side effects they experienced with different dosages of the medications.
User asks about using eucapil/fluridil with Minoxidil and how to space out application to avoid ineffectiveness. Also inquires about microneedling timing.
A 27-year-old male is experiencing a recurring pattern of hair loss after 5 months of using oral minoxidil and finasteride, despite initial success. He is considering using topical androgen receptor blockers like RU58841, pyrilutamide, or clascoterone to address potential androgen receptor hypersensitivity.
The user is experiencing headaches and dizziness two weeks after starting finasteride at 1.25mg, concerned about potential brain fog affecting math studies. They mention hearing that headaches can be normal after starting finasteride.
The conversation discusses concerns about the effectiveness of finasteride for hair loss. The user is worried about being a non-responder to the treatment.
A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hair loss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.
A 35-year-old male is using oral finasteride and ketoconazole shampoo for hair loss and is unsure about seeing improvement after 4 weeks. Suggestions include continuing the current treatment for at least 6 months before expecting results, and considering adding minoxidil to the regimen.
User asks how long to wait after applying minoxidil liquid before applying Fluridil for dry scalp. Topical routine includes minoxidil 2x daily and Fluridil once before bed.
A 20-year-old male experienced mental fog after resuming topical minoxidil for hair loss, questioning if it's due to interactions with antidepressants. Suggestions included trying a lower concentration of minoxidil or alternatives like copper peptides.
Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.
Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.
Hair loss treatments including Minoxidil, finasteride, and ketoconazole 2%. The user shared their progress pictures after using these treatments for one year.
A user asks about the appropriate zinc dosage to offset side effects while taking 0.5 mg of finasteride daily. Responses suggest zinc has a minor effect on hormones compared to finasteride.
OP used minoxidil for 15 months and pyrilutamide for 46 days, achieving desired results without side effects. Users discussed alternatives like dutasteride and finasteride, with concerns about side effects like erectile dysfunction.
The conversation is about finding a reasonably priced shampoo with piroctone olamine in the US. The user is cautious about trying new or smaller brands.
The user experienced no improvement in hair loss with finasteride and minoxidil but had side effects. They plan to add wounding, scalp massage, vitamin K, and taurine supplements to their regimen and seek feedback on these additions.
The user experienced significant hair recovery after 14 months using oral Propecia (finasteride) 1 mg daily and oral minoxidil, and recently added topical minoxidil and topical Propecia to their regimen. The doctor recommended this combination to maximize results, and the user reported no side effects, noticing improvements by the third month.
A user is seeking alternatives to finasteride for hair loss during a planned break for family planning reasons. They inquire about pyrilutamide, cosmern, and other potential future treatments.
Morr F Aqua, an alcohol-free Minoxidil, is discussed for its absorption effectiveness. Users also mention using finasteride and RU58841 for hair loss treatment.
The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.
A user experienced sleep paralysis after starting finasteride and is seeking others' experiences. Another user suggests finasteride might affect neurosteroids, potentially altering sleep patterns.
RU58841 is being mixed with Minoxidil solution, but concerns arise about water causing instability. Mixing with water may lead to hydrolysis, potentially reducing effectiveness.