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      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 6 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.

      community RU58841 from china... Which supplier?

      in Product  6 upvotes 2 years ago
      The conversation is about the quality of RU58841 powder from Shaanxi Laon Biotech. The user is inquiring if anyone has experience with this product.
      Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      community Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      in Minoxidil  146 upvotes 8 months ago
      The user discusses using compounded oral minoxidil due to the ineffectiveness and inconvenience of topical minoxidil for diffuse thinning. They question the efficacy of compounded minoxidil compared to original tablet forms and express concerns about the importance of excipients and binders.

      community Pyrilutamide 0.5 or 0.025% topical fin for maintaining?

      in Basic Questions  91 upvotes 3 months ago
      The user is considering switching from pyrilutamide to 0.025% topical finasteride due to concerns about effectiveness and past side effects from a scalp elixir. They aim to maintain hair until new treatments like breezula or GT00029 become available.

      community Topical 5% minoxidil vs compounded topical spray

      in Minoxidil  3 upvotes 3 months ago
      A user is considering switching from regular 5% minoxidil foam to a compounded 5% minoxidil spray with added caffeine, melatonin, and tretinoin for easier application and potentially better results. Another user mentions that tretinoin can enhance minoxidil's effectiveness by converting it to its active form.

      community Optimal Pyrilutamide (KX-826) Mix and application

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses how to mix pyrilutamide for hair loss treatment, suggesting a mixture of 500mg pyrilutamide with 70% ethanol and 30% propylene glycol, and a potential application dose of 1mL. The user has not personally used pyrilutamide but has researched its preparation and application based on others' experiences.

      community Oral minoxidil and lowering the dose?

      in Minoxidil  1 upvotes 1 year ago
      The user is experiencing significant hair regrowth with 5 mg oral minoxidil and 1 mg finasteride but also side effects like eye puffiness and hypertrichosis. They are considering reducing the minoxidil dose to 2.5 mg to lessen side effects and are curious about caffeine serums for eye puffiness.

      community Formula 82M?

      in Question  4 upvotes 7 years ago
      Formula 82M, a minoxidil and retinol liquid, improved hair texture and filled in temples with baby hairs for the user, but its high cost and lack of reviews cause concern. Another user mentioned using a similar product, 82F, which has become less effective and expensive over time.

      community I found the solution for the Minox dandruff problem

      in Minoxidil  8 upvotes 5 years ago
      A user found a solution for Minoxidil-induced dandruff by using a custom NRF 11.121 mixture from a local pharmacy, which includes ingredients like Isopropyl palmitate and Cremophor RH 40. This formulation prevents dryness and allows better penetration when using hair shaders.

      community Dutasteride with black pepper?

      in Research/Science 1 year ago
      The conversation discusses using black pepper to potentially enhance the absorption of dutasteride for hair loss treatment. It also humorously mentions other unconventional methods and ingredients like grapefruit juice and garlic.

      community Where to buy RU58441 in Germany

      in Product  5 upvotes 2 months ago
      The conversation is about finding a source to buy RU58841 in Germany, specifically looking for a PG-free option. Users suggest buying powder and mixing it themselves, with one user recommending a specific website.

      community PP405 is nothing but a scam and Pelage know it.

      in Chat  78 upvotes 11 months ago
      PP405 is criticized for overhyped claims and cherry-picked data, with doubts about its effectiveness compared to minoxidil and finasteride. Many users express skepticism, emphasizing the need for more comprehensive trial results.

      community questions for the pyrilutamide users here

      in Treatment  7 upvotes 3 years ago
      The conversation discusses the storage and use of pyrilutamide for hair loss, where one user advises against keeping it in the freezer as it may crystallize the active compounds.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 1 year ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 8 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

      in Minoxidil  71 upvotes 3 months ago
      Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 3 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.