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      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       22 upvotes 8 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

      community 24, documentation/pictures. oral fin.

      in Progress Pictures  34 upvotes 6 months ago
      The user is documenting their hair loss journey, using oral finasteride since January 2025, and plans to add microneedling and rosemary oil. They have experienced no further hair loss but no gains, and are considering oral minoxidil due to having pets.

      community Estradiol mesotherapy / idea feedback

      in Female  6 upvotes 1 year ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community This true? Sult1a1 enzyme booster 2025

      in Technology  8 upvotes 1 year ago
      The conversation discusses the potential effectiveness of a Sult1a1 enzyme booster in enhancing the results of minoxidil for hair loss. Users express interest in the booster, hoping it will improve the effectiveness of oral minoxidil, especially for those who struggle with topical application.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 1 year ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community 5 Months Oral Fin Min Biotin Daily

      in Is this regrowth?  36 upvotes 1 year ago
      OP uses 1mg finasteride, 2.5mg minoxidil, and 10mg biotin daily, along with a biotin, caffeine, and saw palmetto shampoo. OP noticed results after 5 months, with occasional heart palpitations from minoxidil.

      community Thoughts on my dermatologist only giving me methionine for AGA?

      in Treatment  4 upvotes 4 years ago
      A dermatologist prescribed methionine with vitamins for hair loss, but the user is doubtful and plans to seek finasteride in France. The user is unsure why finasteride or minoxidil wasn't prescribed, suspecting concerns about side effects or strength.

      community 4 months M26 Fin/Min/Keto/microneedle

      in Progress Pictures  39 upvotes 2 years ago
      A 26-year-old male shared progress pictures after 4 months of treating hair loss with finasteride (1.25 mg on Mondays, Wednesdays, and Fridays), topical minoxidil twice daily, ketoconazole shampoo twice weekly, and weekly microneedling at 1.5 mm. He is seeing hair growth improvement, especially in the front, and is considering hair grafts for the crown area if necessary for more density.

      community My Current Stack: Every Studied Natural at Maximum Concentration

      in Treatment  1 upvotes 7 months ago
      The conversation is about a hair loss treatment regimen using high concentrations of natural ingredients: pumpkin seed oil, saw palmetto, rosemary and peppermint essential oils, and caffeine. The user also practices microneedling, scalp massage, and takes Nutrafol.

      community 10 months of treatment, what do you think?

      in Progress Pictures  5 upvotes 1 year ago
      A user shared their 10-month hair loss treatment progress using 1mg Fin, 2.5mg oral Min, Keto shampoo, dermastamping, and recently added Dut. Replies noted the user had great hair before and after treatment.

      community 2 month progress on diluted hims spray.

      in Progress Pictures  306 upvotes 2 years ago
      A user diluted a Hims spray with Kirkland's minoxidil to lower finasteride concentration and has been applying it for nearly 3 months, noticing baby hairs at the temples. They also use a dermastamp, saw palmetto, and biotin supplements, and are seeking advice on their hair loss stage.

      community Going to try the theory posted here for the next 3-6 months

      in Treatment  187 upvotes 4 years ago
      User xEternex tries hair regrowth with daily broccoli sprouts, apple extract containing procyanidin b2, and microneedling. Others discuss potential issues with the experiment and share their experiences with vegetable consumption and hair growth.

      community Topical Saw Palmetto: An Alternative to Microdosing Topical Finasteride?

      in Product  16 upvotes 2 years ago
      The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.

      community Turkey? Fin? Min? Fin+Min? Biotin? Keto? Saw? Dut? Nut?

      in Satire 4 months ago
      The conversation humorously discusses various hair loss treatments and options, including Minoxidil, finasteride, RU58841, biotin, ketoconazole, saw palmetto, dutasteride, and nutrition. It also mentions hair extensions and hairstyling as methods to achieve desired hairstyles.

      community BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside)

      in Satire 10 months ago
      A satirical post where someone claims to have developed a radioactive isotope scalp serum using Polonium-210 that outperforms Minoxidil and finasteride for hair regrowth. The serum reportedly stimulates DNA repair in hair follicles, leading to significant hair density increase, but the post is met with skepticism and concerns about safety.

      community 47M - 12 months of topical min/fin feedback

      in Finasteride/Dutasteride  1 upvotes 6 months ago
      A 47-year-old man has been using a topical spray containing minoxidil, finasteride, biotin, and ketoconazole for hair loss but has not seen any regrowth and is experiencing more hair loss. He is considering switching to a pill form due to frustration with the lack of results.

      community Supplements for Health hair as for Gemini & Grok

      in Chat  1 upvotes 4 months ago
      The conversation discusses various supplements and vitamins like Vitamin D3, K2, Biotin, Iron, Zinc, and B Vitamins for improving hair health. It also mentions a combination of Tocotrienols, Pycnogenol, Saw Palmetto, Pumpkin Seed Oil, Stinging Nettle, and Myricetin for stabilizing hair, with Saw Palmetto, Pygeum, and Stinging Nettle noted for thickening hair despite side effects.

      community 2 months progress on topical fin and min.

      in Is this regrowth?  51 upvotes 1 year ago
      The user experienced significant hair improvement after two months of using topical finasteride, minoxidil, and biotin, despite initial heavy shedding. They used 0.3% finasteride and 7% minoxidil once daily, and obtained the products from Hims.

      community Here's a recommended bloodwork panel before starting Fin.

      in Finasteride  11 upvotes 9 years ago
      The conversation provides a detailed list of blood tests recommended before starting finasteride to establish a baseline for monitoring potential side effects. A shorter list is also provided for those with limited funds, and the user shares personal experience of using finasteride without issues for about nine years.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 3 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community M40 - 3 Months progress on Fin/Min

      in Is this regrowth?  1442 upvotes 5 months ago
      A user reported significant hair regrowth after 3 months using 1mg oral finasteride, 1ml 5% topical minoxidil, and microneedling, along with biotin, vitamin D, iron, and zinc supplements. They are optimistic about continued progress despite initial skepticism.

      community 20M, 2.5 months, 1mg fin, topical min(local)

      in Progress Pictures  125 upvotes 1 year ago
      A 20-year-old male shares his 2.5-month progress using 1mg finasteride, topical minoxidil, tretinoin, dermarolling, and ketoconazole for hair loss, noting slight libido decrease. Users discuss sourcing topical finasteride and request more photos to see the results.