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GlossaryMethicillin-Resistant Staphylococcus Aureus

bacteria resistant to many antibiotics, including methicillin (MRSA)

Methicillin-Resistant Staphylococcus Aureus (MRSA) is a type of bacteria that has developed resistance to many antibiotics, including methicillin. This makes infections caused by MRSA more difficult to treat and can lead to more severe health issues, particularly in hospital settings where patients may have weakened immune systems.

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community P-1075: a BETTER version of Minoxidil

in Research/Science 7 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community A warning to anyone considering 3rd party sourcing PP405 or its analogs

in Treatment 31 upvotes 2 months ago

Be cautious when sourcing PP405 or its analogs from third-party suppliers due to potential safety risks and lack of regulatory approval. The conversation highlights concerns about counterfeit products and the absence of reliable testing, making it risky to use such treatments.

community Don't use PP405 from everychem. it is likely fake.

in Research/Science 66 upvotes 11 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

community PG causing irritation when applying RU

in Research/Science 2 years ago

The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

community Anyone heard of scube3? And other emerging treatments?

in Research/Science 4 upvotes 1 year ago

Emerging hair loss treatments like PP405, a topical MPC inhibitor, show promise in activating stem cells for hair growth. The conversation seeks information on the development stages and accessibility of these treatments.

community China clinics pushing “PT88/PT66 / SP88/SP66 mesotherapy ampoules” + I have seb derm — anyone heard of this / any evidence?

in Research/Science 6 upvotes 5 months ago

The user is exploring hair loss treatments in China, currently using finasteride and minoxidil, and is concerned about seborrheic dermatitis. Clinics are recommending selenium sulfide, doxycycline, and mesotherapy ampoules like PT88/PT66 or SP88/SP66, but the user is unsure about their effectiveness.

community Setipiprant/PGE2 feedbacks?

in Question 4 upvotes 8 years ago

The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.

community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga

in Technology 9 upvotes 4 months ago

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.

community Approve PP405 quickly you coward

in Satire 193 upvotes 11 months ago

Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

community Black market pp405? Title title

in Treatment 8 upvotes 4 months ago

PP405 is likely fake, and JXL069 is an unrefined prototype with unknown side effects. It's advised to wait for the official PP405 release.

community If PP405 goes systemic this would be quite catastrophic

in Research/Science 4 upvotes 1 year ago

Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

community Oral PTD-DBM available online, worth giving a shot?

in Research/Science 4 upvotes 6 years ago

Oral PTD-DBM was discussed as a potential hair loss treatment, but it was deemed ineffective in humans despite promising results in mice. The conversation concluded that trying it without VPA might be unwise.

community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting

in Chat 30 upvotes 2 months ago

PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.

community Poor man's PP405? Can't help but keep on thinking about this...

in Technology 6 upvotes 2 months ago

Lactic acid is not effective for hair growth when applied topically. JXL069, finasteride, and minoxidil are suggested as alternative treatments.

community Can I put pp405 into a dermastamp

in Microneedling 2 upvotes 8 months ago

The conversation is about using a dermastamp for hair loss treatment and concerns about a potentially scam product, pp405. It suggests sticking with known treatments like finasteride and minoxidil.

community Isn’t Minixidilmax’s PG solvent just superior to the Anageninc K&B solvent

in Product 1 upvotes 1 year ago

PG solvent is considered superior to K&B solvent for RU58841 and Pyralutamide due to cost and effectiveness. The user questions why they should use K&B when PG offers more benefits.

community Does anyone know of the actual effectiveness of the DP2 inhibitors?

in Question 4 upvotes 8 years ago

Setipiprant and Fevipiprant are questioned for their effectiveness in hair maintenance, with skepticism due to lack of convincing results beyond vellus hair growth. The user is satisfied with Minoxidil and Finasteride but is curious about the potential of DP2 inhibitors.

community PP405, a new hair growth stimulant that is completely different from minoxidil.

in Product 109 upvotes 1 year ago

PP405 is a new hair growth stimulant different from Minoxidil, currently in phase 2 trials. Users discuss its potential, safety concerns, and the long wait before it might be available.

community [21M] seb derm + probably mbp.

in Research/Science 4 upvotes 3 years ago

Minoxidil and finasteride are being considered for hair loss due to seborrheic dermatitis and male pattern baldness. The user is also using ketoconazole and zinc pyrithione shampoo.

community Apparently you can try PP405 right now!?

in Research/Science 33 upvotes 1 year ago

PP405 is likely a scam, with concerns about its legitimacy and safety, as it may cause unintended tissue growth. Users suggest sticking to known treatments like finasteride and minoxidil.

community Micro needling and ptd-dbm progress

in Progress Pictures 5 upvotes 4 years ago

The conversation is about using micro needling and PTD-DBM for hair loss treatment. The user applies PTD-DBM drops on weekdays and performs micro needling weekly.

community Sprinkle that PP405 on my scalp like I sprinkle salt on my stake

in Research/Science 119 upvotes 10 months ago

PP405 shows promise for hair growth with significant results after 4 weeks, but skepticism exists due to its unavailability. Some users are hopeful for its potential, while others express concerns about side effects and market release delays.

community Pp405 any site for buying in Europe

in Product 1 month ago

PP405 is not commercially available or legitimate in Europe. Users are discussing the lack of availability of this product.

community PP405 Identity Research

in Research 292 upvotes 9 months ago

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

community Trialing the probiotics BB536, PTA 6475 so you don’t have to

in Research/Science 73 upvotes 11 months ago

Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

community The amazing fast pace of PP405.

in Chat 327 upvotes 7 months ago

PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

community Fighting Seb Derm + MPB - Winning

in Progress Pictures 74 upvotes 8 months ago

The user successfully managed hair regrowth by using a combination of finasteride, dutasteride, minoxidil, and specific shampoos to treat seborrheic dermatitis. They emphasize the importance of maintaining a healthy scalp and are considering food intolerance tests to further address inflammation.

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

in Research/Science 5 upvotes 2 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community Will PP405 render Minox and Fin obsolete?

in Research/Science 26 upvotes 11 months ago

PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.

community New company created by Dr. Kang-Yell Choi to commercialize PTD-DBM therapy

in Research/Science 10 upvotes 5 years ago

PTD-DBM therapy for hair loss is being developed by Dr. Kang-Yell Choi, with human testing planned in South Korea. Some clinics in the U.S. offer PTD-DBM/valproic acid therapy, but it hasn't completed trials yet.