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      community Anyone experimenting with Melatonin?

      in Treatment  4 upvotes 4 years ago
      Melatonin is being explored as a hair loss treatment, with one user mixing it into minoxidil but not seeing results. The conversation discusses experimenting with melatonin concentrations.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 4 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 1 year ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

      community Musely's topical hair solution

      in Finasteride/Dutasteride  6 upvotes 3 years ago
      The conversation discusses a topical hair loss treatment containing 0.1% dutasteride, 6% minoxidil, tretinoin, and ketoconazole. The user is asking for opinions on the effectiveness of this solution.

      community 0.25 alfatradiol or 0.5 Pyrulitamide ?

      in Product  4 upvotes 8 months ago
      The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Any clinical study on cysteine alone for hair loss?

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.

      community Lysine IS helping

      in Update  4 upvotes 5 years ago
      Lysine supplementation at 2 grams daily reduced hair shedding by 25% and made hair strands thicker. The user highly recommends lysine for hair health.

      community Anyone looking at peptides for hair?

      in Treatment  9 upvotes 4 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community My final attempt at creatine with fin

      in Product  41 upvotes 10 months ago
      Creatine may cause hair shedding and texture changes, with mixed user experiences. Combining creatine with finasteride doesn't always prevent these effects, possibly due to individual DHT sensitivity.

      community Gray market sources to get gt20029 or pp405?

      in Product  2 upvotes 1 year ago
      The conversation is about sourcing gray market compounds, gt20029 and pp405, for hair loss treatment. The user is interested in these compounds despite their unproven status and potential risks.

      community Carnitine Tartrate + Potassium chloride + Niacin

       7 upvotes 11 years ago
      The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

      community Tretinoin to add to Minoxidil - where to find it

      in Minoxidil  2 upvotes 1 year ago
      The user is using a solution of Finasteride, Minoxidil, and Tretinoin, which increases Minoxidil's effectiveness. They are seeking a reliable source of Tretinoin to add to over-the-counter Minoxidil solutions.

      community Pyrilutamide cease and desist from Kintor

      in Transplants  12 upvotes 3 years ago
      Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

      community Creatine and increased MPB Hair Loss

      in Chat  10 upvotes 4 years ago
      Creatine may increase hair loss in those with male pattern baldness (MPB) due to increased DHT, but whey protein generally does not affect hair loss. Finasteride and minoxidil are used to manage hair loss, and some users report increased shedding with creatine but not with whey protein.

      community Openminded Creatine Discussion

      in Product  10 upvotes 9 months ago
      Creatine may cause hair shedding in some individuals, particularly those with genetic sensitivity to hair loss, but this is not universally experienced. Finasteride users report mixed results, with some experiencing resumed shedding when taking creatine.

      community ZeroMino from Minozidilmax composition

      in Product  2 upvotes 3 years ago
      Hair loss discussion involves ZeroMino from Minoxidilmax, with ingredients like Azelaic acid, Adenosine, Biotin, Caffeine, Niacinamide, Retinol, and Melatonin. Company refuses to disclose concentration of ingredients.

      community Does CosmeRNA target the root cause of MPB?

      in Chat 3 years ago
      . CumsOnYourFeet69 has been discussing a new treatment called CosmeRNA which claims to target the root cause of male pattern baldness, and is considering using it in conjunction with Minoxidil instead of Finasteride due to possible side effects. Replies have highlighted that the efficacy of this treatment is still unknown, but it could be used as an effective maintenance option if successful.