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      community 21 Month Finasteride+13 Month Minoxidil+2 Month Stemoxydine

      in Finasteride/Dutasteride  89 upvotes 2 years ago
      The post discusses a 21-month treatment of hair loss using Finasteride, a 13-month treatment with Minoxidil, and a 2-month treatment with Stemoxydine. Replies suggest enhancing results by adding a micro needling pen and tretinoin to the regimen, and consider Finasteride and Minoxidil as crucial treatments.

      community 1 year of treatment with Fin, Min, keto (M24)

      in Progress Pictures  5 upvotes 1 year ago
      A user has been treating hair loss for a year with Finasteride, oral Minoxidil, microneedling, and ketoconazole shampoo, recently adding Dutasteride. They are unsure about the effectiveness and seek advice on whether to continue or switch fully to Dutasteride.

      community Estimate of GT20029 on the grey market?

      in Technology  8 upvotes 2 years ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Best carrier for pyrilutamide?

      in Update  9 upvotes 3 years ago
      The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community My current nuclear stack. Thoughts?

      in Chat  6 upvotes 2 years ago
      The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

      community Can you mix different topicals into 1 solution?

      in Chat  2 upvotes 1 year ago
      Combining minoxidil, pyrilutamide, and copper peptide is questioned, with advice to apply them separately to avoid reactions. Finasteride and minoxidil are recommended for effectiveness.

      community 5 months on minoxidil and finasteride

      in Is this regrowth?  54 upvotes 3 months ago
      The conversation is about hair regrowth treatments using minoxidil, finasteride, tretinoin, and ketoconazole shampoo. Users discuss their experiences, including side effects, shedding, and the potential benefits of adding microneedling.

      community I am doing an experience with RU58841

      in Treatment 6 months ago
      The conversation discusses a user experimenting with RU58841 for hair regrowth by ingesting it, which others find concerning. There are mentions of potential side effects and comparisons to other treatments like minoxidil, finasteride, and flutamide.

      community Finasteride and Metformin together?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The conversation is about whether it's safe to take Metformin for weight loss and Finasteride together, with the concern that Finasteride is not commonly used for hair loss treatment in the user's location, and their doctor is not knowledgeable about it.

      community oral minoxidil + fin + biotin progress

      in Progress Pictures  65 upvotes 10 months ago
      The user resumed finasteride and added 5mg oral minoxidil and biotin, noticing quick progress in hair regrowth. Other users discuss dosages and express surprise at the results.

      community Can a HT fix a severe case of diffuse thinning scalp?

      in Chat  1 upvotes 1 year ago
      The user has severe diffuse thinning on the scalp and is using finasteride, topical minoxidil, dermarolling, tretinoin, and Nizoral without satisfactory results. They are considering a hair transplant but are concerned about the cost and the number of grafts needed.

      community Topical solutions combining minoxidil and finasteride?

      in Treatment  2 upvotes 8 months ago
      A user is seeking advice on creating a topical solution combining minoxidil, finasteride, and tretinoin for hair loss, and is unsure about optimal concentrations and availability. Another user shares their custom formula with tretinoin 0.015%, finasteride 0.025%, and minoxidil 5%, and mentions taking oral dutasteride 0.25mg daily.

      community Non-responder to minoxidil for years

      in Microneedling  2 upvotes 3 months ago
      A 22-year-old has been using minoxidil and finasteride for hair loss with initial success, but later experienced increased shedding and no regrowth. They recently added vitamin D3 supplements and microneedling, which reduced shedding, but are seeking advice on regrowth, with suggestions to try tretinoin with minoxidil and consider dutasteride.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 3 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community I'm starting to believe [m34, bald 10 years, 50 days treatment]

      in Progress Pictures  70 upvotes 1 year ago
      A user shared progress pictures after 50 days of using finasteride, topical minoxidil, and ketoconazole shampoo for hair loss, noting significant hair growth and expressing surprise at the results. They plan to continue the treatment and possibly incorporate a dermastamp and increase minoxidil application if growth plateaus.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.