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      community 21M 9 months of 1mg Fin/2.5 Min

      in Finasteride/Dutasteride  25 upvotes 1 year ago
      A 21-year-old has been using 1mg finasteride and 2.5% minoxidil for 9 months with some improvement in hair density. They plan to add collagen, 1% ketoconazole shampoo, and biweekly microneedling to their routine.

      community Making topical finasteride solution

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user has been mixing finasteride with stemoxydine for hair loss and is considering switching to a less expensive product with a different ingredient list. They are questioning if the new product's higher water content compared to alcohol will affect the finasteride's solubility.

      community Min / Fin - M21 - 1.5 Year Update - Multiple Sheds

      in Update  15 upvotes 1 year ago
      The user experienced significant hair regrowth using 5% topical minoxidil and 1mg finasteride daily, despite multiple shedding phases, and emphasizes the importance of starting treatment early and maintaining consistency. They advise against obsessing over online forums during shedding periods and recommend checking for scalp conditions like seborrheic dermatitis and ensuring proper nutrition.

      community Do-it-yourself topical melatonin?

      in Product  12 upvotes 3 years ago
      The conversation is about creating homemade topical melatonin for hair loss, with one person suggesting adding melatonin to stemoxydine as a potential treatment.

      community Pp405 - lowkey kinda bad results

      in Treatment  16 upvotes 1 year ago
      PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  5 upvotes 2 months ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community Studies show: 0.2 mg reduces scalp DHT by ~55%. 1 mg reduces it by ~64%. 5 mg reduces it by ~69%.

      in Finasteride/Dutasteride  148 upvotes 8 months ago
      Finasteride reduces scalp DHT significantly even at low doses, with 0.2 mg reducing it by about 55%, but higher doses like 1 mg and 5 mg offer only marginally more reduction. Users discuss side effects, with some experiencing none and others reporting issues like low libido, and they also mention using other treatments like minoxidil and dutasteride.

      community GT20029 - Promising phase II results

      in Research/Science  15 upvotes 2 years ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community Is PP405 formula available in grey market?

      in Treatment  16 upvotes 1 year ago
      The conversation is about the availability of the PP405 formula for hair loss treatment, with mentions of finasteride and its side effects. Users discuss the potential of obtaining the formula through unofficial channels and the challenges related to its genetic sequence and delivery method.

      community Genomic Sequencing for Hair Loss

      in Research/Science  156 upvotes 2 months ago
      Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

      community Getting PP405. Now…. or as soon as possible

      in Research/Science  145 upvotes 1 year ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

      community 6 months before and after pics: VDPHL01 (oral minoxidil)

      in Progress Pictures  111 upvotes 1 year ago
      A user shared their positive experience with a clinical trial for a new oral medication, VDPHL01, which is a reformulated version of oral minoxidil taken at a high dose of 17mg daily, showing significant hair regrowth after six months. The user noted that this formulation is believed to be more effective and time-released, with fewer side effects compared to regular oral minoxidil.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community 1.25mg oral minoxidil-3 month progress

      in Progress Pictures  633 upvotes 1 year ago
      A 44-year-old man experienced significant hair regrowth after switching from topical to 1.25mg oral minoxidil and 0.5mg daily finasteride, with no side effects. He noticed hair thickening after two months and credits the oral form's effectiveness.

      community DNA Test for better suited treatment?

      in Treatment  3 upvotes 8 months ago
      The conversation is about hair loss treatments, specifically discussing the use of dutasteride, minoxidil, and the potential benefits of a DNA test and PRP therapy. Opinions vary, with some users skeptical about the DNA test and PRP, suggesting sticking with current treatments.

      community M20 : Need advice on starting minoxidil

      in General  114 upvotes 1 year ago
      The user is experiencing hair thinning and increased hair fall, and is considering using minoxidil for 3-4 months but is concerned about the long-term commitment and potential hair loss after stopping. They have tried multivitamins, serums, and shampoos, and are hesitant about starting PRP treatment.

      community 4 months Oral Minoxidil 1.25 mg Daily (33 M)

      in Progress Pictures  520 upvotes 3 years ago
      This user, "ediblediety", has been taking oral minoxidil (1.25 mg daily), keto shampoo and occasional derm-rolling for 4 months to treat their hair loss, and they have experienced a shedding phase after the first few weeks of use. They report improvements in the thickness of their facial and body hair, but note that this may be daunting to women.