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      community Min/Fin is pure magic. Seriously. Read below

      in Treatment  9 upvotes 1 year ago
      A user reported significant hair growth improvements using 1mg finasteride and 2.5mg minoxidil daily, despite minor side effects. The doctor advised against combining multiple treatments to identify what works.

      community 1mg Fin ED, 5% min twice a day (m20)

      in Is this regrowth?  108 upvotes 1 month ago
      The user experienced significant hair regrowth using 1mg finasteride daily and 5% minoxidil twice a day over 6.5 months, improving from a Norwood 3.5 to a Norwood 2. Despite progress, they still feel their hair is thin, especially at the temples.

      community Musely s Exosome formulation looks interesting

      in Chat  13 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community 6 month progress, 20M, 1mg Fin

      in Progress Pictures  6 upvotes 1 month ago
      A 20-year-old shared six months of hair regrowth progress using 1mg finasteride, 5% topical minoxidil, and recently started using a derma stamp. The user is pleased with the results and obtained finasteride through an online pharmacy.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  53 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community two months on 2-deoxy-d-ribose (2ddr)

      in Progress Pictures  10 upvotes 11 months ago
      The conversation discusses hair regrowth using 2-deoxy-d-ribose (2DDR) combined with minoxidil, with some users noting new hair growth. The original poster has been using minoxidil for 12 years and is considering combining 2DDR with finasteride, despite past side effects.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  7 upvotes 3 years ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community DNA Test for better suited treatment?

      in Treatment  3 upvotes 8 months ago
      The conversation is about hair loss treatments, specifically discussing the use of dutasteride, minoxidil, and the potential benefits of a DNA test and PRP therapy. Opinions vary, with some users skeptical about the DNA test and PRP, suggesting sticking with current treatments.

      community New molecule PP405 vs exercise

      in Research/Science  38 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community 4.5 months on 1mg fin/6%min/2.5mg biotin hybrid progress

      in Is this regrowth?  59 upvotes 1 year ago
      A 25-year-old male experienced hair regrowth after 4.5 months using a chewable treatment with 1mg finasteride, 6% minoxidil, and 2.5mg biotin, despite initial shedding and acne from accutane. Opinions on progress vary, with some noticing thicker hair and others seeing no difference or thinning.

      community Retinol substitute for Tretinoin

      in Minoxidil  4 upvotes 1 year ago
      The user is seeking a substitute for Tretinoin to enhance the effectiveness of Minoxidil for hair loss. They are considering using Retinol as an alternative.

      community 23m asian progress - minoxidil + micro + vitamin

      in Progress Pictures  38 upvotes 2 years ago
      A 23-year-old Asian male shared progress pictures after 3 months of using minoxidil, microneedling for 1.5 years, and taking vitamin supplements. Replies suggest adding finasteride or dutasteride for long-term hair maintenance.

      community Whats up with Prolactine these days?

      in Research/Science  20 upvotes 3 years ago
      The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

      community which is better ; minoxidil with more alcohol or more pg?

      in Minoxidil  4 upvotes 3 years ago
      The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.

      community Treatment prognosis, 22M

      in Treatment  4 upvotes 5 years ago
      A 22-year-old male with hair loss is considering treatments like finasteride, minoxidil, and derma rolling after being diagnosed with MPB, vitamin D deficiency, and dandruff. He seeks advice on whether these treatments can realistically improve his hair density and achieve a healthier NW2.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 8 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.