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A new hair loss treatment, Pyrilutamide, has been released and is claimed to be a strong anti-androgen, potentially effective when used with finasteride. However, there are mixed opinions on its effectiveness and safety, with some users skeptical and others purchasing it.

The user is considering switching from topical Minoxidil to oral Minoxidil due to concerns about maintaining a topical routine. They have already started finasteride and are trying to prevent further hair loss progression.

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

A user shared their positive experience with a 3-month oral minoxidil and finasteride treatment from Hims, noting healthier hair and no significant side effects. Others in the conversation discussed their own experiences with similar treatments, costs, and additional methods like microneedling and topical minoxidil.

After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.

Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

The conversation discusses how to use fluridil/topilutamide with other hair loss treatments like liquid minoxidil and CB-03-01, considering fluridil's hydrophobic nature and potential degradation with water. The user questions the necessity of washing hair only once per week as suggested by the manufacturer.

The user switched from topical to oral finasteride, reduced their use of topical minoxidil, and started using XL hair serum with a mesogun injector. They are seeing hair regrowth even with a lowered dose of minoxidil and are considering oral minoxidil for the future.

The user reported significant hair regrowth and stopped hair loss after using Pyrilutamide and Minoxidil for four months. They found Pyrilutamide effective in blocking DHT locally without side effects, preferring a gray market version over Koshine's product.

The user "OP" uses a combination of topical minoxidil 5%, finasteride 0.025%, and caffeine to combat hair loss, with noticeable results over 5-6 months. Side effects include unwanted body hair growth and an itchy scalp, but no significant sexual side effects.

The user has been taking 0.25mg of oral finasteride daily for a month and is considering increasing the dose to 1/3 of a pill. They have also been using topical minoxidil for several years.

ScottMills3 shared how to quickly get a prescription for generic Dutasteride (Dut .5mg) online through MedicalWellnessCenter, which cost $69.95 for the consultation and $31 for a 90-day supply. Another user suggested hidrb.com as a cheaper alternative, offering the same prescription for $15.

Hair loss treatment with topical finasteride/minoxidil, which had good results after 3.5 months of application. The user also asked if there was any reason to take the oral pill version and if anyone has ever tried mixing them together.

A 24-year-old with mild temple recession is using 5% minoxidil without noticeable effects and has started topical finasteride but is anxious about potential side effects. They are considering a specialist visit for peace of mind despite the cost.

The user experienced heart palpitations from using Fin (0.1%) and Min (10%) and is seeking alternatives. Options suggested include PRP or Mesotherapy, with a recommendation to try topical Fin without Min.

The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

The conversation discusses using 2% Pyrilutamide from Anagenica for hair loss, as the user did not see results with 1% Pyrilutamide. The user is considering increasing the dosage but is concerned about the cost.

A 26-year-old male used 1mg oral finasteride and 5% topical minoxidil for a year, noticing progress despite initial skepticism and minor side effects. He applied minoxidil to both the hairline and entire scalp, and attempted microneedling but discontinued due to sneezing.

The conversation discusses the safety and cost of 2.5mg Dutasteride, and the potential for increased DHT reduction by combining Dutasteride with topical Finasteride. The original poster is currently using 0.5mg Dutasteride, 1.25mg oral Minoxidil, and a topical treatment, and is considering increasing the dosage to maximize results while avoiding less known treatments like RU58841.

The conversation discusses using a 0.1% topical finasteride solution twice daily after experiencing brain fog from oral finasteride. A user suggests trying the solution once daily for a few months if concerned.

The conversation discusses unconventional methods of taking finasteride, with suggestions ranging from crushing it into coffee to using pill boxes or reminders. Users also humorously suggest alternative methods like mixing with food or drinks, but generally advise against altering the pill's form.

GT20029 and pyrilutamide are both androgen antagonists but work differently; GT20029 degrades the androgen receptor, while pyrilutamide blocks DHT from binding. GT20029 is expected to have similar efficacy to CosmeRNA.

Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

A 35-year-old man shares his one-year progress using 1.25 mg oral finasteride and 5% topical minoxidil for hair loss, with no side effects and slight improvement in his front hairline. He also uses keto shampoo twice a week and a 0.5mm roller weekly.

A user is seeking advice on treating a chin scar with Verteporfin, noting that higher doses were more effective. Another user responds that they do not use it, without providing further explanation.

The new formulation includes minoxidil, finasteride, redensyl, caffeine, and propacil, and removes alcohol. The user is concerned about potential hair shedding due to the change in ingredients.

A user is considering using verteporfin with microneedling, oral/topical minoxidil, and RU58841 to treat hair loss. They seek advice on dosage and application methods.

Stopping antihistamines may resolve neurological side effects when using finasteride. Users experienced muscle aches, headaches, and lethargy when combining the two.

A user from India discusses using a topical solution containing Minoxidil (50mg) and Finasteride (1mg) twice a day for thinning hair and Norwood 2/3. The dermatologist recommended it for maintenance with slim chances of regrowth, and the user seeks advice on its use.