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      community Galenic lotion. Science behind the components

      in Treatment  1 upvotes 9 months ago
      A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

      community NMN supplementation experiences?

      in Research/Science  2 upvotes 2 months ago
      The conversation discusses experiences with NMN supplementation for hair growth, with some users reporting increased hair growth activity and others seeing no significant changes. OP has been using dutasteride and oral minoxidil, and recently added NMN, noticing increased shedding, which they hope indicates new hair growth.

      community Diluting DIY topical finasteride

      in Finasteride/Dutasteride  2 upvotes 7 months ago
      A user is discussing making a DIY topical finasteride solution using ingredients like water, alcohol, propylene glycol, ethanol, and glycerin, and is concerned about the stability of the mixture. Other users suggest that the solution will work and discuss the importance of propylene glycol for drug dissolution and factors like temperature and light affecting finasteride stability.

      community Why do I see so many people here recommend microneedling?

      in Microneedling  108 upvotes 3 years ago
      The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

      community Microneedling : Questions regarding routine and sanitary

       7 upvotes 7 years ago
      The conversation discusses microneedling for hair regrowth, emphasizing the importance of disinfecting the scalp to avoid infections. It also mentions using minoxidil and castor oil in the treatment routine.

      community Can absorption be intervened by oil, sebum etc?

      in Treatment  3 upvotes 1 year ago
      The conversation discusses whether oily scalp and sebum can hinder the absorption of topical hair loss treatments like Minoxidil and Finasteride, even when using tretinoin. The user is skeptical about the effectiveness of these treatments due to their oily scalp condition.

      community Crystals in Minoxidil bottle

      in General  89 upvotes 11 months ago
      Minoxidil bottle developed crystals, possibly due to air exposure, but the trichologist advised not to worry. The user questions the advice, noting the lack of recommendations for finasteride or derma rolling.

      community 7 months progress fin/min/microneedling

      in Progress Pictures  125 upvotes 1 week ago
      A 30-year-old shared their 7-month hair regrowth progress using topical minoxidil twice daily, 1 mg finasteride daily, and weekly microneedling. Users discussed the effectiveness of these treatments and suggested adding retinol for better results.

      community Needling project, I'm needling half of my head

      in Microneedling  1 upvotes 1 year ago
      A person is experimenting with microneedling on one temple while using Minoxidil to address hair loss. They plan to needle weekly and apply Minoxidil twice daily, avoiding application around needling sessions.

      community Oral minoxidil + microneedling - pointless?

      in Microneedling  19 upvotes 1 year ago
      Oral minoxidil is considered effective for hair growth, and some users combine it with microneedling despite mixed opinions on its additional benefits. Concerns about microneedling include potential scarring and lack of conclusive evidence on its effectiveness when used with oral treatments.

      community Ru58841 + topical minoxidil + microneedling succes story

      in Progress Pictures  337 upvotes 1 year ago
      A user shared their successful hair loss treatment using RU58841, topical minoxidil, and microneedling, noting significant improvement over three months. They chose RU58841 over finasteride due to personal preference and reported no side effects, while others discussed their experiences with different treatments and supplements.

      community Verteporfin mixing solute for transplants

      in Treatment  12 upvotes 2 years ago
      Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.

      community any minox non-responders turn to good responders after adding microneedling or tretinoin?

      in Minoxidil  7 upvotes 3 years ago
      The conversation is about someone who initially had positive results with Minoxidil for hair loss, lost those gains due to a hospital stay, and is now not seeing the same results upon resuming treatment. They plan to add microneedling and/or tretinoin to their regimen and are seeking success stories from others who did not respond to Minoxidil alone.

      community 2 months of 1mg Finasteride daily , %5 minoxidil 2x daily, Nizoral Shampoo and 1.5mm depth microneedling weekly

      in Progress Pictures  228 upvotes 1 year ago
      A user shared progress pictures after using 1mg Finasteride daily, 5% Minoxidil twice daily, Nizoral Shampoo, and weekly microneedling at 1.5mm depth for two months, reporting no side effects and discussing their routine and supplements. Commenters reacted positively, with one advising caution with creatine and another endorsing the benefits of microneedling.

      community Making minoxidil + azelaic acid type recipes?

      in Minoxidil  7 upvotes 6 years ago
      The conversation is about making a hair loss treatment combining minoxidil with azelaic acid, retinol, and caffeine, similar to the product Xandrox. The user has tried Xandrox but switched to Kirkland minoxidil for cost reasons and is seeking advice on creating a similar mixture.

      community How often microneedle/ top min

      in Minoxidil  6 upvotes 3 months ago
      Microneedling should be done every 1-2 weeks, with a recommended wait of at least 24 hours before applying topical minoxidil. Finasteride is planned to be used daily at 1mg.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 7 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community M19 Minoxidil and microneeddling 0.5mm

      in Chat  2 upvotes 3 months ago
      The conversation discusses hair loss treatments, specifically using Minoxidil, microneedling, and finasteride. The user is concerned about worsening hair loss and is advised to consider finasteride.