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      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

      community When should we get the next news about PP405

      in Chat  25 upvotes 7 months ago
      Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.

      community PROGRESS ON NEW ROUTINE - DUT/Minox/Microneedling

      in Progress Pictures  6 upvotes 6 months ago
      The conversation is about a user's hair loss treatment progress using a routine of Avodart (Dutasteride), oral and topical Minoxidil, Ketoconazole shampoo, and microneedling. The user reports no side effects and shows improvement after resuming consistent treatment.

      community only microneedling and supplements

      in Progress Pictures  67 upvotes 9 months ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community Should I apply minoxidil here and microneedle?

      in Minoxidil  5 upvotes 3 months ago
      The conversation discusses using minoxidil and microneedling to potentially thicken small hairs on the forehead after a hair transplant. It also mentions the importance of using an oral DHT blocker for hair growth.

      community RU58841 dilution in Minoxidil Vs PG+Ethanol

      in Treatment  5 upvotes 2 years ago
      RU58841 mixed with Minoxidil seems less effective over time, so the user plans to switch to a PG and Ethanol dilution for better results. They also consider using rosemary oil with Minoxidil to enhance RU58841 absorption.

      community Minoxidil + Microneedling, 2 months results

      in Progress Pictures  20 upvotes 2 years ago
      The user has been using minoxidil twice daily for 2.5 months to treat hair loss and has seen great results, despite only microneedling once at the start. They occasionally forget a dose but it hasn't affected their positive outcome.

      community 7 months dutasteride minoxidil microneedling 25y.o. Some progress.

      in Progress Pictures  349 upvotes 11 months ago
      A 25-year-old shared progress in hair regrowth after 7 months using dutasteride, minoxidil, and microneedling, noting some baby hair growth on the temples. The user plans to continue this treatment, having found it effective despite some initial shedding and challenges with styling due to topical minoxidil.

      community Ordered PTD-DBM from tailor made

      in Product  4 upvotes 5 years ago
      The conversation discusses hair loss treatments, including finasteride, microneedling, minoxidil, and PTD-DBM. The user has not noticed significant regrowth and is considering cost-effective options like valproic acid.

      community MWC compounded Minoxidil + Tretinoin

      in Minoxidil 1 year ago
      A user is considering using compounded Minoxidil with Tretinoin from Medical Wellness Center to improve hair growth. They are also curious about the effects of higher Minoxidil doses and adding Tretinoin to their regimen.

      community Actifolic RU58841 and others Scam?

      in Treatment  4 upvotes 3 years ago
      Actifolic's RU58841 and Pyri products are perceived as ineffective, with users reporting no side effects or improvements, suggesting possible quality issues. Users recommend alternative sources and emphasize the importance of timing when using RU58841 with Minoxidil.

      community What’s the deal with microneedling?

      in Microneedling  15 upvotes 3 months ago
      A 26-year-old uses topical minoxidil, oral finasteride, and Nizoral shampoo for hair thinning and is considering microneedling but is unsure about the best approach. Users suggest using a 1.0mm dermaroller once a week, cautioning against overuse due to potential scarring, and some recommend combining microneedling with minoxidil for better absorption.

      community How am i suppoused to use RU58841?

      in Technology  5 upvotes 2 years ago
      A user mixed 3g of RU58841 with Kirkland Minoxidil and noticed a gooey precipitate forming. They are seeking advice on what went wrong.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community 3 months on Finasteride-Minoxidil-Microneedling 36M

      in Is this regrowth?  2 upvotes 2 months ago
      A 36-year-old male has been using finasteride, 5% minoxidil foam, and microneedling with a 0.75mm dermastamp or Dr. pen for three months. He notices thicker hair and reduced hair loss, with high testosterone and normal DHT levels, while managing prolactin levels with vitamin B6.

      community RU58841 from china... Which supplier?

      in Product  6 upvotes 2 years ago
      The conversation is about the quality of RU58841 powder from Shaanxi Laon Biotech. The user is inquiring if anyone has experience with this product.

      community ru58841 in europe, without getting water in the mail.

      in Product  1 upvotes 3 months ago
      The conversation is about finding a trustworthy and affordable source for RU58841 in Europe, with a comparison between Anagenic and Actifolic. The user seeks experiences from others in the EU to avoid receiving water instead of the product.

      community Epibiotech Hair Multiplication

      in Technology  16 upvotes 4 years ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also references Epibiotech's hair multiplication and cell therapy as potential solutions.

      community Which mesotherapy should I choose?

      in Research/Science  1 upvotes 2 years ago
      A user is considering adding PRP and mesotherapy to their hair loss treatment and is deciding between two options: Promoitalia, which contains Phosphatidic acid, Riboflavin, and Superoxide dismutase, and the more expensive Melsmon, a human placenta derivative. They seek advice on which option to choose based on effectiveness and scientific backing.

      community NW7 recovery attempt, a little over 2 month progress. 1.25mg fin, 5mg topical minox twice a day. Pyrilutamide for 1 month, switched to RU58 2 weeks ago, weekly microneedling 1.5mm

      in Treatment  9 upvotes 3 years ago
      A user is attempting to recover from severe hair loss using 1.25mg finasteride, 5mg topical minoxidil twice daily, pyrilutamide for a month, RU58841 for two weeks, and weekly microneedling at 1.5mm. They have seen new hair growth after two months and plan to continue the treatment for a year with the hope of regrowing enough hair for a transplant.