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      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Microneedling and massaging scalp progress

      in Progress Pictures  7 upvotes 4 years ago
      A user shared their hair restoration journey using oral and topical finasteride, experiencing side effects with the former. They later switched to microneedling, scalp massages, and vitamins (D3, Zinc, Biotin, B complex, Vitamin E) with mixed feedback on progress.

      community Any anecdotes about tretinoin and min?

      in Minoxidil  7 upvotes 1 year ago
      The conversation discusses the effectiveness of combining tretinoin with minoxidil for hair loss. The user notes better results from microneedling rather than the tretinoin and minoxidil combo.

      community Brainstorming: upping your dermarolling game

      in Research/Science  4 upvotes 2 years ago
      The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.

      community 1.5 years on topical fin + min

      in Progress Pictures  234 upvotes 10 months ago
      The user has been using 0.25% topical finasteride and 5% minoxidil for 1.5 years with significant hair improvement and plans to start microneedling and possibly switch to oral finasteride for better long-term results. They are happy with the progress but seek more hair density and have not experienced any side effects.

      community Combining daily microneedling and redlight is a game changer

      in Microneedling  22 upvotes 1 year ago
      The conversation discusses using daily microneedling at 0.25mm and red light therapy to enhance hair regrowth, especially when traditional treatments like finasteride and minoxidil become less effective. The combination is said to improve hair density and thickness, with red light therapy being more cosmetic, while microneedling is essential for challenging areas.

      community Is it safe to use topical 5% Min and 3mg Min together?

      in Minoxidil  2 upvotes 1 year ago
      A 36-year-old man is using topical 5% Minoxidil for hair thinning and is considering adding 3mg Minoxidil pills as recommended by a dermatologist. He is concerned about potential side effects and increased shedding but cannot access Finasteride due to strict regulations.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 2 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 6 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  40 upvotes 2 years ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.

      community Verteporfin trials in hair transplant patients begin

      in Transplants  41 upvotes 3 years ago
      A clinical trial for Verteporfin as a hair loss treatment, and the potential for greater progress in treatments for hair loss in the future. Common treatments such as Minoxidil, Finasteride and RU58841 were discussed.

      community Topical finasteride carrier vehicle

      in Finasteride/Dutasteride  1 upvotes 7 months ago
      The user is using a topical solution containing 1% finasteride and 5% minoxidil for hair loss, with water, glycerin, and PEG-40 hydrogenated castor oil as carrier agents. They are questioning if these ingredients are effective carriers after using the solution for three months.

      community Minoxidil is working for me – just 3 months in! (No fin, no microneedling

      in Is this regrowth?  48 upvotes 8 months ago
      A 36-year-old experienced slow, diffuse hair thinning over 15 years and saw significant improvement using 5% topical minoxidil alone for 3 months, without finasteride or microneedling. The user is pleased with the results, noting increased hair density and no visible scalp, and plans to continue monitoring progress without using hormone-affecting treatments.

      community Using essential oils as well as minoxidil?

      in Minoxidil  5 upvotes 8 years ago
      The conversation is about using a blend of coconut oil, peppermint oil, and rosemary oil with minoxidil for hair loss, and whether it's safe to apply this blend after microneedling.

      community M29 Dut/Min/Microneedle/Tretinoin

      in Is this regrowth?  26 upvotes 1 year ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

      community Why I really believe the tension theory is the cause of MPB

      in Research/Science  70 upvotes 4 years ago
      The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

      community On Fin 1 mg for past 4 months, plus micro needling weekly

      in Progress Pictures  17 upvotes 1 year ago
      A 49-year-old man has been using 1 mg of finasteride daily and microneedling weekly for four months to address hair loss, with no side effects and noticeable progress. He shares his experience and encourages others to consider treatment options without fear.