The acne medication Winlevi, which contains Clascoterone, is available in the U.S. and may slow down hair loss until a higher concentration treatment, Breezula, is released.
A 23-year-old experiencing severe diffuse thinning after scalp inflammation is considering finasteride as a last resort after stopping minoxidil and using anti-inflammatory medication. Users suggest that inflammation causes temporary shedding and recommend consulting a dermatologist, with some advocating for finasteride as a reliable treatment option.
A user experienced dark under-eye bags while using Minoxidil, which improved after switching from liquid to foam but led to hair loss. They also used retinol cream and a dermastamp but are seeking advice on effectively combating eye bags.
The conversation is about using tretinoin to improve the response to Minoxidil for hair loss treatment. No specific protocol for tretinoin application is provided.
Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.
The user noticed hair thinning and has been using a treatment with minoxidil 2%, hydrocortisone butyrate, and 17 alpha estradiol for three months, seeing some regrowth. The user had dermatitis, now cured, which worsened the hair loss.
A 33-year-old woman shared her successful hair regrowth journey using topical Minoxidil 5% once daily, resulting in thicker hair and increased confidence. She avoided oral treatments like finasteride due to potential side effects and focused on consistent application of Minoxidil.
Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.
The user reports significant hair regrowth using a topical solution of 5% minoxidil and 0.1% finasteride twice daily, along with derma rolling twice a week. They have not experienced shedding and are optimistic about continued hair growth.
MaximusDurkimus shares experience with 0.25mg Finasteride, Minoxidil-induced lupus, and less than 10mg RU58841 for hair loss. Plans to try 0.025% topical Finasteride with 5% Stemoxydine and possibly Tretinoin, Fluridil, or CB-03-01 in the future.
The user has been using topical finasteride and minoxidil for a month to address hair thinning. They are experiencing shedding but have noticed small hairs on their temples.
The conversation is about a user's progress in treating diffuse hair thinning using a topical regimen including finasteride, minoxidil, ketoconazole, microneedling, saw palmetto, collagen, and vitamins, along with lifestyle changes. The user plans to switch from topical to oral finasteride for potentially better results.
The user experienced sexual side effects from finasteride and switched to using only topical minoxidil without side effects. They are seeking alternatives to finasteride, such as topical finasteride, to maintain hair without adverse effects.
The user has been using 1mg finasteride daily, 2.5mg minoxidil daily, topical tretinoin three times a week, and topical minoxidil daily from June 2023 to June 2025 without noticeable improvement in hair loss. Suggestions include switching to dutasteride and increasing oral minoxidil to 5mg daily, but concerns about long-term health effects are raised.
The user has been treating hair loss for 7 months using a combination of pyrilutamide, a topical mix of finasteride and minoxidil, microneedling, a topical mix of GHK-Cu and minoxidil, ketoconazole shampoo, fish collagen peptides, zinc, and vitamin D3. Another user suggests that continuous small improvements could lead to significant hair regrowth over time.
Minoxidil and tretinoin can cause scalp dryness and itchiness. Using Nizoral, aloe, a lighter minoxidil formula, or a water-based moisturizer like one with hyaluronic acid may help alleviate these issues.
Minoxidil may cause increased prolactin levels, leading to side effects like puffy nipples and chest tenderness. Users experienced these issues and considered stopping minoxidil while continuing or switching to other treatments like finasteride, microneedling, and supplements.
The user is seeking advice on a hair loss treatment called Ell Cranell, which contains Alfatradiol. Another user shared information from a study stating that Alfatradiol only slows down or stabilizes hair loss, but does not increase hair density or thickness.
Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.
Mixing Pyrilutamide powder with Minoxidil solution is being considered. The Minoxidil solution contains Minoxidil 5%, Azelaic acid 5%, ABN complex 0.8%, Retinol 0.025%, Caffeine 0.001%, and a delivery vehicle.
A user with diffuse thinning, currently using finasteride, biotin, minoxidil, and nizoral shampoo, is considering a topical solution called "82M" but is skeptical due to its high cost and lack of supporting research. They seek others' experiences with "82M."
After 5 months using 1mg oral finasteride, 2ml topical minoxidil, 3mg oral minoxidil, biotin, and shampoo with nioxin and nizoral, the individual saw decent hair improvement but is not fully satisfied yet.
A 31-year-old uses Minoxidil, RU58841, Reviv Hair Serum, and Ketoconazole shampoo for hair loss but avoids finasteride. They plan to reintroduce red light therapy (LLLT) and Eucapil despite previous shedding concerns.
Minoxidil is causing severe scalp irritation, including itchiness and dryness, for the user. Alternatives suggested include anti-fungal treatments, propylene-glycol-free formulations, and possibly oral minoxidil.
This conversation is about a user's progress pictures after using minoxidil twice a day and microneedling for 1.5 months, with other users recommending finasteride as an additional treatment. They are also discussing the frequency and depth of the microneedling.
User sees possible hair regrowth using minoxidil and 0.5 dermaroller weekly for 2.5 months. Others suggest checking progress in 6 months and considering finasteride, but user experienced side effects from it.
PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.
The user shared a 4-month hair loss treatment update, using Kirkland liquid minoxidil twice daily, microneedling with 1.5mm and 0.5mm needles, and applying rosemary oil twice a week. They plan to start taking finasteride and also grew a beard by microneedling and applying minoxidil to their face.