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      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 2 years ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community is anyone using ru58841 against acne?

      in Technology  3 upvotes 1 year ago
      RU58841 is discussed as a potential treatment for acne and hair loss, with users debating its effectiveness and safety compared to other treatments like finasteride, minoxidil, and dutasteride. Concerns about RU58841's side effects and lack of clinical trials are raised, while some users share their personal experiences and routines involving RU58841 for hair loss.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  447 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Does CosmeRNA target the root cause of MPB?

      in Chat 3 years ago
      . CumsOnYourFeet69 has been discussing a new treatment called CosmeRNA which claims to target the root cause of male pattern baldness, and is considering using it in conjunction with Minoxidil instead of Finasteride due to possible side effects. Replies have highlighted that the efficacy of this treatment is still unknown, but it could be used as an effective maintenance option if successful.

      community I'm already DOING EVERYTHING!!!

      in Female  26 upvotes 5 years ago
      A 26 year old female dealing with hair loss who is considering treatments such as Spiro, minoxidil and finasteride. Other potential solutions mentioned are PRP treatment, a wig, and bio-identical estrogen combined with bica.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community how about progesterone cream?

      in Research/Science  22 upvotes 1 year ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community Diffuse thinning fucking sucks

      in Update  430 upvotes 2 years ago
      The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 2 years ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

      community PSA: If you're prone to MPB dont take creatine

      in Update  106 upvotes 2 years ago
      Creatine might speed up hair loss in those prone to male pattern baldness, possibly due to increased DHT levels. Some users experience no issues when using creatine with treatments like finasteride, minoxidil, or dutasteride.

      community 3 months. Dut, Min, Keto, Vitamin D, exercise

      in Progress Pictures  353 upvotes 3 years ago
      A user's experience using dutasteride, minoxidil, ketoconazole, vitamin D, scalp massage, exercise, and avoiding vaping and 2-in-1 shampoo/conditioner to treat hair loss; they also discussed the side effects of finasteride.

      community How uninformed the general public is about hair loss

      in Chat  319 upvotes 2 years ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

      community An updated, simple guide to the most effective hair loss treatments

       193 upvotes 6 years ago
      Effective treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, Dermarolling, LLLT, PRP, Ketoconazole, and Scalp Massage. In addition, anti-inflammatory diets and stress management are recommended to maintain or regrow hair.

      community Should I get transplant #4 or just shave my head?

      in Transplants  171 upvotes 1 year ago
      A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 3 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community 1600 grafts (~5500 hairs) | 10 month results

      in Transplants  1669 upvotes 9 months ago
      The user received 1600 hair grafts but is dissatisfied and plans a second transplant for better coverage. They use minoxidil and finasteride and are considering adding dutasteride.

      community ~1 year using rosemary shampoo (trigger warning)

      in Progress Pictures  158 upvotes 2 years ago
      A user reported hair thickening and a stronger crown after using rosemary shampoo for about a year, with progress pictures as evidence. Some commenters discussed the effectiveness of natural treatments versus pharmaceutical options like Minoxidil and Finasteride.

      community My Pyrilutamide Experience Update 2, Part 1

      in Update  63 upvotes 3 years ago
      The user's experience taking Pyrilutamide, a drug for hair loss treatment, and their use of it in combination with other treatments such as Minoxidil, Finasteride and RU58841. They have experienced positive results so far with no major side effects.

      community It’s over. NOTHING has worked.

      in Chat  95 upvotes 3 years ago
      A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

      community Homemade topical spironolactone

      in Research/Science  26 upvotes 3 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.