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      community 4 years of dutasteride monotherapy

      in Progress Pictures  191 upvotes 2 years ago
      The conclusion of the conversation is that the user experienced noticeable regrowth of hair after using dutasteride as a single treatment for about 1.5 years. No before photos were available.

      community Source for Pyrilutamide has disappeared

      in Treatment  21 upvotes 3 years ago
      Anageninc stopping the sale of Pyrilutamide due to a cease and desist order from Kintor, with some speculating that it was either a hoax or subpar product.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2444 upvotes 5 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community M26 - 9 months after hair transplant! AMA

      in Transplants  624 upvotes 6 years ago
      A user who underwent a hair transplant in Istanbul to reduce balding, and the discussion of various treatments such as finasteride and growth hormone for preventing further hair loss.

      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 2 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community GT20029 Phase 2 results are out

      in Treatment  60 upvotes 5 months ago
      GT20029 shows promising results for hair loss treatment, with potential approval in China by 2026 or 2027, but U.S. approval may take longer. It could serve as an alternative to finasteride, with a potentially better side effect profile.

      community Why you may be taking Dutasteride wrong

      in Finasteride/Dutasteride  63 upvotes 6 months ago
      Dutasteride is more effective than finasteride for hair loss, with optimal dosing at 0.5mg once or twice a week to minimize side effects. Topical application may further reduce side effects while effectively lowering scalp DHT.

      community How many years can we expect PP405 to be on the market

      in Product  12 upvotes 9 months ago
      PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.

      community Why do so many people trash on finasteride?

      in Chat  247 upvotes 1 year ago
      Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

      community 11 years of finasteride usage 1 mg a day

      in Finasteride/Dutasteride  419 upvotes 1 year ago
      A user shared their 11-year experience with finasteride, noting temporary increased shedding that stopped, and advised continuing the treatment despite seasonal shedding. They reported no side effects and maintained a full head of hair.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 1 year ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community 4 months 0.25 mg finasteride only

      in Progress Pictures  167 upvotes 1 year ago
      A user shared their 4-month progress using 0.25 mg finasteride daily for hair loss, reporting significant improvement and minimal side effects. Other users discussed their experiences with different dosages and side effects.

      community How is there still no consensus on Topical Dutasteride in 2024?

      in Finasteride/Dutasteride  147 upvotes 2 years ago
      The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 2 years ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Mid 40s Fin only - 12 month update.

      in Progress Pictures  508 upvotes 2 years ago
      A user in their mid-40s shared a 12-month update on using finasteride for hair loss, showing significant improvement. They started seeing thicker hair and regrowth after 3 months, with no side effects noticed.

      community Dutasteride 1 year regression. Depressing. (With pictures for proof)

      in Progress Pictures  14 upvotes 2 years ago
      A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

      community Is DUT better or worse than FIN?

      in Finasteride/Dutasteride  62 upvotes 2 years ago
      The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.

      community Dermatologist told me to quit fin after turning 40

      in Finasteride/Dutasteride  194 upvotes 2 years ago
      A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

      community Warning: Danish Nordic Hair Growth is scam!

      in Product  86 upvotes 2 years ago
      A Danish citizen warns against NordicHairGrowth.com, claiming it falsely advertises products for treating androgenic alopecia. The company's ingredients and claims are disputed, including a non-existent patented ingredient RP-24, and a non-verifiable clinical trial.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community where does the renewed spironolactone hype come from?

      in Research/Science  8 upvotes 3 years ago
      Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

      community Why am I so scared to start fin?

      in Finasteride/Dutasteride  15 upvotes 4 years ago
      User is scared to start finasteride for hair loss due to potential side effects and personal concerns. Another user suggests trying a low dose for 6 months and avoiding online groups to reduce anxiety.