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      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 9 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community An *insane* RU58841 success story

      in Progress Pictures  95 upvotes 1 year ago
      RU58841, oral and topical minoxidil, finasteride, and ketoconazole shampoo led to significant hair regrowth, though some suspect a hair transplant. Concerns about RU58841's side effects, like anxiety and heart issues, were discussed.

      community RU + Oral Minox / DUT + Topical Minox

      in Progress Pictures  35 upvotes 2 years ago
      The individual has been using minoxidil for beard growth for over two years, started oral minoxidil and dutasteride six months ago, and began RU58841 three months ago, which significantly enhanced their results. They are open to answering questions about their hair loss treatment experience.

      community Jxl069 (pp405 api) week 8 update

      in Progress Pictures  200 upvotes 10 months ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Welp - pp405 conference showed nothing

      in Update  77 upvotes 2 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community waiting for hope DIY pp405 guy that will save us😡😡😔

      in Satire  38 upvotes 7 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community 4 month is in - 2 pics - fin/min+

      in Progress Pictures  386 upvotes 1 year ago
      The user shared a 4-month update on their hair regrowth journey using finasteride, minoxidil, and microneedling, reporting significant progress and styling ability. They emphasized persistence, shared their regimen details, and addressed side effects like weaker erections and blurry vision, which improved with lifestyle changes.

      community Ru58841 made my hair worse

      in General  138 upvotes 1 year ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community I am having Success with RU58841 and 1mm Derma Roller

      in Microneedling  19 upvotes 4 years ago
      A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 11 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Thanks bruh, I appreciate yall

      in Progress Pictures  65 upvotes 1 year ago
      The user experienced hair growth improvement using a 1.25mm microneedle weekly, oral finasteride, oral minoxidil, and rosemary oil. They plan to switch to generic finasteride and minoxidil for safety concerns.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community I’m taking Veradermics VDPHL01 - AMA

      in Treatment  174 upvotes 1 month ago
      A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.

      community Hair Loss Treatment Iceberg Chart

      in Satire  1378 upvotes 4 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.

      community 33M 1mg finasteride + topical minoxidil

      in Progress Pictures  59 upvotes 4 months ago
      A 33-year-old man shares his positive hair regrowth results using 1mg finasteride daily, 5% topical minoxidil twice daily, and a 0.5mm dermaroller weekly. He feels more confident and encourages others to try the routine despite potential side effects.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 6 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.