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      community The pessimism about the Crisp Cas 9 is excessive

      in Chat  11 upvotes 8 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community Whats up with Prolactine these days?

      in Research/Science  20 upvotes 3 years ago
      The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

      community P5P supplementation for fin sides.

      in Treatment  7 upvotes 4 years ago
      P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 6 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community 3 months update on meds post HT

      in Progress Pictures  111 upvotes 1 year ago
      The user started using 1mg finasteride and Regaine foam post-hair transplant, noticing significant hair growth at three months. They experienced testicular cramps as a side effect but no other issues, and are considering microneedling for further improvement.

      community Pyrilutamide cease and desist from Kintor

      in Transplants  12 upvotes 3 years ago
      Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  57 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Breezula Phase 3 Results enough for maintenance?

      in Treatment  11 upvotes 1 month ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community RU58841 from china... Which supplier?

      in Product  6 upvotes 2 years ago
      The conversation is about the quality of RU58841 powder from Shaanxi Laon Biotech. The user is inquiring if anyone has experience with this product.

      community Full extent of pp405 effectiveness

      in Treatment  14 upvotes 7 months ago
      The conversation discusses the potential effectiveness and future results of the hair loss treatment pp405, with questions about its impact on different hair loss stages and areas. There is anticipation for phase 3 trial results to provide more data, and hope that pp405 could enhance hair transplant outcomes.

      community PP405 (Everychem 3HP) Users, share your story!

      in Chat  32 upvotes 2 months ago
      Everychem's solution, similar to PP405, has mixed results for hair regrowth, with some users reporting improvements and others seeing no change or worsening hair loss. Users are sharing experiences and updates to determine its effectiveness.

      community Pyrilutamide from Ligand Chem in the UK

      in Research/Science  4 upvotes 3 years ago
      Pyrilutamide from Ligand Chem was used by several individuals to address hair loss, with mixed results and no significant side effects reported. Some users switched to Minoxidil Max for better value, while others noted no hair growth or only a reduction in shedding.

      community GT20029 & KX826 Major Updates from Kintor.

      in Research/Science  104 upvotes 1 year ago
      KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.

      community SCUBE 3 (the last hair bender)

      in Research/Science  2 upvotes 11 months ago
      SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinical trials. No specific updates or new information are provided in the conversation.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 11 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Just introduced RU wish me luck!! (+ whats working for me) NO MIN!

      in Treatment  5 upvotes 2 years ago
      The user is using finasteride, RU58841, and various natural supplements and treatments like seamoss, fish oil, and black rice water spray to combat hair loss, avoiding minoxidil due to dependency concerns. They report thicker hair and regained confidence, while discussing the potential risks and benefits of RU58841 with others.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community Chances of GT20029 hitting the black market?

      in Treatment  11 upvotes 2 years ago
      The conversation is about the potential availability of GT20029 on the black market and whether users would try it. Participants advise waiting for phase 3 trial results to ensure safety and efficacy.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 8 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community Any news on scube3? It's my only hope at this point guys. Where are things with it? How far away is it? Could be available in 2024?

      in Technology  8 upvotes 2 years ago
      The conversation is about a person rapidly losing hair and seeking information on the availability of a new treatment called scube3, as they have experienced side effects from current treatments like Minoxidil and finasteride. They are hoping scube3 will be approved soon as they believe it's their only remaining option.