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      community An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects

      in Research/Science  1 upvotes 5 years ago
      The conversation discusses a botanically derived treatment for androgenetic alopecia using ingredients like saw palmetto, green tea, and evening primrose, showing impressive results over 270 days. Concerns include the study's uncontrolled nature and potential product motivation, with suggestions to enhance absorption through derma rolling.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 8 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community What’s the highest minox % you home brewed ?

      in Minoxidil  2 upvotes 1 year ago
      A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

      community Is there any new drug that looks promising ?

      in Research/Science  24 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Be careful with minoxidil, even if it's just foam.

      in Minoxidil  12 upvotes 1 year ago
      Minoxidil caused side effects like chest pain and tinnitus for the user, leading them to stop using it and consider switching to finasteride with microneedling. Other users shared similar experiences with minoxidil, while some reported no issues, highlighting varied individual reactions.

      community Important detail for Oral Minoxidil users

      in Minoxidil  9 upvotes 1 month ago
      Oral minoxidil users should monitor heart health with periodic echocardiograms and cardiologist visits due to potential side effects. While some experience serious side effects, they are rare, and the benefits for hair growth often outweigh the risks.

      community COQ10 + PQQ for scalp inflammation??

      in Chat  6 upvotes 1 year ago
      A 32-year-old male with diffuse thinning and seborrheic dermatitis has been using finasteride for 8 months without improvement. He is considering COQ10 + PQQ supplements for scalp inflammation and hair loss.

      community Can I use coconut/rosemary oil or should I use minoxidil

      in Chat  1 upvotes 4 months ago
      The conversation is about hair loss treatments, with a focus on using coconut/rosemary oil, minoxidil, and finasteride. Oils may help with scalp health, but minoxidil is for regrowth, and finasteride or dutasteride is needed to stop hair thinning.

      community RU58841 has gotten rid of my acne

      in Product  1 upvotes 8 months ago
      RU58841, combined with 5% minoxidil, helped reduce acne and hair loss. Users discussed using RU58841 cream for acne and shared experiences with other treatments like finasteride and dutasteride.

      community 6 weeks 5mg min 0.5mg dut progress

      in Progress Pictures  7 upvotes 1 year ago
      A 35-year-old man shares his positive progress in hair regrowth using a daily routine of 5mg oral minoxidil and 0.5mg dutasteride, along with a low light cap, weekly dermarolling, and biweekly ketoconazole shampoo. He reports noticeable improvements without side effects and aims to inspire others considering similar treatments.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 2 months ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community I guess I’m cooked. 1mg fin/day 2.5 mg min/day + topical tretinoin (3x/week) + topical min/day. June 2023-june 2025

      in Progress Pictures  2 upvotes 10 months ago
      The user has been using 1mg finasteride daily, 2.5mg minoxidil daily, topical tretinoin three times a week, and topical minoxidil daily from June 2023 to June 2025 without noticeable improvement in hair loss. Suggestions include switching to dutasteride and increasing oral minoxidil to 5mg daily, but concerns about long-term health effects are raised.

      community Anyone wanna try and interview the developers of RU?

      in Research/Science  83 upvotes 5 years ago
      The conversation discusses arranging an interview with the developers of RU58841 to clarify its safety and reasons for halted research, with some users expressing concerns about potential risks and others citing financial reasons for the discontinuation of studies. Specific treatments mentioned include RU58841, minoxidil, and finasteride.

      community My cat died just from touching 2% minoxidil

      in Minoxidil  5181 upvotes 11 months ago
      Minoxidil is highly toxic to cats and can be fatal with minimal exposure. Users suggest switching to oral minoxidil or taking precautions to prevent pet exposure.

      community My current stack/personal program

      in Update  1 upvotes 1 year ago
      The user is using RU58841, Revivogen, Regenepure ketoconazole shampoo, and plans to use a stimufield cap to address hair loss. They aim to avoid finasteride and minoxidil while hoping to stop hair loss and regrow hair.

      community Serious Oral Minoxidil Side Effects

      in Minoxidil  30 upvotes 4 years ago
      A user experienced severe side effects, including heart-related symptoms, after increasing their oral minoxidil dosage to 5 mg, leading them to stop the medication and seek medical advice. Many users advised against high doses of oral minoxidil, suggesting anxiety as a possible cause, and recommended consulting a doctor or switching to topical treatments.

      community M20 - Thick hairline totally demolished during topical Minoxidil shedding (stringy, weak, density loss, see through)

      in Minoxidil  7 upvotes 3 years ago
      Stefano, a 20-year-old male, experienced significant hairline shedding and thinning after using topical Minoxidil, along with rosemary/jojoba oil, biotin tablets, caffeine shampoo, and a dermaroller. He is uncertain whether to continue the treatment in hopes of regrowth or stop and potentially return to his original hair condition, while a reply suggests using finasteride or dutasteride to address the underlying cause of hair loss.

      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  8 upvotes 6 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.