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      community Sons altering formula, clinically sound or greed?

      in Product  6 upvotes 3 months ago
      A user is concerned about a change in the formula of Sons topical treatment, which now requires fewer sprays but contains less minoxidil. They question if the change is for convenience or if it's a way to charge the same for less product.

      community Those who experienced a big shed and stuck to their routine long term (1yr+) - Did a big shed truly mean you got good results down the line?

      in Chat  8 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically the use of minoxidil, finasteride, and microneedling, and the experience of shedding hair as a potential sign of treatment effectiveness. Some users report positive results after initial shedding, while others express concerns about long-term hair loss and the effectiveness of treatments.

      community Breezula Phase 3 Results enough for maintenance?

      in Treatment  11 upvotes 1 month ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community 24 topical min 2x a day and fin 1mg results + microneedling

      in Progress Pictures  305 upvotes 1 year ago
      The user shared positive results from using Minoxidil twice daily, Finasteride 1mg, and microneedling for hair loss, noting improved hair density and mental health. They emphasized the importance of consistency and patience, mentioning initial shedding phases but no significant side effects.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Fallopia multiflora (Fo-Ti) for Hair Regrowth?

       3 upvotes 12 years ago
      Fo-Ti is discussed as a potential treatment for hair loss, but its effectiveness is questioned. Users express skepticism and caution about its use.

      community A reminder that Telogen Effluvium could look like MPB; my progress

      in Progress Pictures  30 upvotes 3 years ago
      A 19-year-old male experienced significant hair loss, initially thought to be male pattern baldness (MPB), and used minoxidil and briefly finasteride. After realizing the issue was telogen effluvium (TE), he improved his diet and supplemented with vitamins, which led to substantial hair regrowth.

      community Shoutout to the mice that tested our Minoxidil

      in Satire  147 upvotes 1 year ago
      The conversation humorously acknowledges the role of mice in testing Minoxidil for hair loss while also discussing the ethics of animal testing. Some users argue against animal testing, citing cruelty, while others defend its necessity for medical advancements.

      community 25M - 6 months of treatment with topicals

      in Is this regrowth?  52 upvotes 2 months ago
      A 25-year-old male has been treating hair loss for six months using 5% minoxidil once daily, 0.02% DIY topical finasteride once daily, and microneedling every two weeks. He reports increased hair density and some regrowth, particularly vellus hairs, and plans to continue the regimen, possibly adding oral finasteride in the future.

      community What became of this PROMISING theory?

      in Research/Science  9 upvotes 1 year ago
      The conversation discusses skepticism and mixed opinions about a hair loss theory, mentioning treatments like Minoxidil, finasteride, RU58841, and Procyanidin B2. There is criticism of a content creator named HairCafe and the difficulty in obtaining effective sulforaphane supplements.

      community RU58841 Permanently Fixed Balding In Unexpected Way.

      in Satire  123 upvotes 7 months ago
      The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

      community "When comparing 5% minoxidil with 0.60 mm or 1.20 mm needle lengths, Faghihi et al. found that 0.60 mm needle lengths led to significant hair count and diameter increases versus 5% minoxidil, whereas 1.20 mm needle lengths only saw hair count increases versus 5% minoxidil"

      in Research/Science  60 upvotes 2 years ago
      Microneedling with 0.6 mm needles combined with 5% minoxidil is more effective for hair count and thickness than minoxidil alone or with 1.2 mm needles. Biweekly microneedling at 0.6 mm depth is recommended for better results in treating androgenetic alopecia.

      community 2.5 years later, don’t give up kings. Stay consistent

      in Progress Pictures  403 upvotes 2 years ago
      The conversation is about someone sharing their 2.5-year hair regrowth journey using finasteride and topical minoxidil, emphasizing the importance of consistency and patience with these treatments. They also mention using tea tree conditioner and experiencing no side effects from oral finasteride.

      community Just a rule of thumb regarding "the cure™"

      in Chat  8 upvotes 4 months ago
      Be skeptical of claims about new baldness cures; current treatments like finasteride, dutasteride, and minoxidil remain the best options. New products like Breezula and PP405 lack compelling evidence and may not be available soon.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community New hair growing in small clusters

      in Is this regrowth?  4 upvotes 1 month ago
      The user is experiencing hair regrowth in small clusters using oral minoxidil, oral finasteride, a red light cap, and Nizoral 2% shampoo. They are hopeful for continued improvement and thicker hair.

      community Welp - pp405 conference showed nothing

      in Update  77 upvotes 2 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community blood flow and scalp tension - put up or shut up

      in Chat  31 upvotes 8 months ago
      The conversation discusses skepticism about the effectiveness of scalp tension theory and scalp massagers for hair regrowth, contrasting it with treatments like finasteride and minoxidil, which have more user-reported results. Participants question the belief in scalp tension theory, suggesting it may be a marketing tactic, while others argue for a multifactorial approach to hair loss.

      community Is Koshine (KX-826) worth the risk?

      in Treatment  5 upvotes 10 months ago
      OP is considering using KX-826 for hair loss due to side effects from other treatments like Minoxidil and finasteride. Users discuss the risks and safety of KX-826, with some suggesting caution due to its status as a research chemical.

      community Potential role of TB-500 Thymosin Beta-4

      in Technology  8 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, RU58841, and TB-500 Thymosin Beta-4. It critiques the credibility of biohacking claims.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.