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      community Prepare to be disappointed by PP405

      in Research/Science  23 upvotes 4 months ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

      community I was a non-responder to Minoxidil before my esophagus surgery

      in Research/Science  38 upvotes 2 years ago
      The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

      community Starting Pyrilutimide 5% Update

      in Treatment  1 upvotes 2 years ago
      The user started using Pyrilutamide 5% for hair loss and has not experienced side effects after two days. They previously had side effects from Fluridil and topical Minoxidil 5%, and their hair continued thinning with topical Spironolactone.

      community Aggressive diffuse thinning after 1 year of fin and min

      in Progress Pictures  7 upvotes 1 year ago
      The user is experiencing aggressive diffuse thinning despite using 1mg oral finasteride daily, topical minoxidil twice, microneedling, and Nizoral for seborrheic dermatitis. They are considering switching to dutasteride or RU58841 but are advised to seek a second opinion to determine the cause of hair loss.

      community 5 months of nuking T, 2 months of minoxidil

      in Transgender  487 upvotes 1 year ago
      The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

      community Before and after, 5 months of fun and microneedling.

      in Progress Pictures  8 upvotes 4 months ago
      The user shared progress pictures after 5 months of using finasteride and microneedling, noting they stopped minoxidil recently to test finasteride alone. Another user observed good improvement and advised not to stop using minoxidil.

      community Minoxidil results in 3 months after stopping fin

      in Is this regrowth?  469 upvotes 1 year ago
      The user stopped finasteride due to testicular aches and switched to minoxidil, seeing positive results in three months. They are considering topical finasteride but are cautious because of past side effects from oral use.

      community Five Months Progress - Min/Fin

      in Progress Pictures  15 upvotes 10 months ago
      The user shared five months of progress using oral finasteride, topical minoxidil, and supplements like biotin, zinc, omega-3, and collagen. They noted encouraging results, while others suggested trying oral minoxidil or microneedling for potentially better outcomes.

      community M34, diffuse thinning since 20ish. Few more months to go?

      in Is this regrowth?  104 upvotes 5 months ago
      A user shared their positive experience with hair regrowth using finasteride, genuine minoxidil, and dermastamping, noting significant improvement after switching from a fake minoxidil product. They advised others to verify the authenticity of minoxidil through a bleach test to avoid counterfeit products.

      community 1mg Fin ED, 5% min twice a day (m20)

      in Is this regrowth?  108 upvotes 1 month ago
      The user experienced significant hair regrowth using 1mg finasteride daily and 5% minoxidil twice a day over 6.5 months, improving from a Norwood 3.5 to a Norwood 2. Despite progress, they still feel their hair is thin, especially at the temples.

      community Bicalutamide vs Finasteride for female AGA plus TE

      in Female  3 upvotes 3 months ago
      OP is considering Bicalutamide for female AGA and TE but is concerned about its side effects and effectiveness compared to Finasteride. OP is also using Minoxidil and Spironolactone but is experiencing significant shedding and is unsure if it's androgen-driven or due to Minoxidil changes.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community 1 Year Progression M18 - Detailed

      in Progress Pictures  30 upvotes 2 weeks ago
      The user experienced significant hair regrowth using finasteride, minoxidil, and microneedling, but saw a decline after reducing treatments and stopping gym workouts. They plan to restart microneedling and consider a hair transplant in the future.

      community Saw Palmetto/Pumkin seed gives basically same results as Fin

      in Treatment 1 year ago
      A user reported that Procerin, containing Saw Palmetto and Pumpkin seed oil, provided similar hair thickening results as finasteride but with milder side effects. They experienced reduced libido and watery ejaculations but are adjusting the dose to minimize these effects.

      community Finasteride treatment after 15 months

      in Finasteride/Dutasteride  14 upvotes 1 month ago
      The user has been using finasteride and topical minoxidil for 15 months but is experiencing constant hair shedding, similar to telogen effluvium, despite stable widow peaks. They have checked for vitamin and mineral deficiencies, consulted specialists, and are considering further investigation like a scalp biopsy.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community No shedding but temples & frontal receeding

      in Finasteride/Dutasteride 8 months ago
      A 24-year-old male started using finasteride and minoxidil for hair loss, noticing reduced hair fall but continued temple and frontal recession. He uses both oral and topical minoxidil, biotin, vitamin D, and coal tar shampoo, and experiences rare heart palpitations.

      community my 3.5 months progress on finasteride 1 mg

      in Progress Pictures  276 upvotes 1 month ago
      The user experienced significant hair regrowth after 3.5 months of using finasteride 1 mg daily, despite stopping minoxidil after three weeks. They were surprised by the results and noted some weight gain but no significant side effects.

      community 1.5 yrs on min+ fin. Dut switch?

      in Is this regrowth?  24 upvotes 2 months ago
      The user has been using oral finasteride and minoxidil for 1.5 years with some crown improvement but still experiences thin hair and a receding hairline. They are considering switching to dutasteride for potentially better results, while others suggest adding topical minoxidil back into the routine.

      community 2 years of fin and minoxidil progress.

      in Progress Pictures  2168 upvotes 1 year ago
      A 37-year-old reported significant hair regrowth and increased confidence after two years of using oral finasteride and topical minoxidil, with no side effects. They are satisfied with the results and are reconsidering the need for a hair transplant.

      community 8 months on fin and 4 months on minox

      in Progress Pictures  1422 upvotes 1 year ago
      The user experienced significant hair regrowth using 1mg oral finasteride daily and a walnut-sized amount of minoxidil foam once a day. They started balding at 17 and reported no side effects from the treatments.