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      community Fighting Hair loss AND Grey Hair

      in Treatment  2 upvotes 3 years ago
      OP is exploring ways to stop or reverse greying hair, using NAC and considering PABA supplements. Some users suggest hair dye, black strap molasses, and copper as potential solutions.

      community Ghk-cu + c60 + saw palmetto oil

      in Treatment  5 upvotes 6 years ago
      The conversation discusses using GHK-Cu, C60, and saw palmetto oil as treatments for hair loss. Specific treatments mentioned include Minoxidil (Min), Finasteride (Fin), and RU58841 (RU).

      community Can selenium be harmful to hair?

      in Product  6 upvotes 3 years ago
      The user experienced increased hair shedding after taking a multivitamin containing selenium and questioned if selenium was the cause. The conversation revolves around the potential negative effects of selenium on hair health.

      community What’s the highest minox % you home brewed ?

      in Minoxidil  2 upvotes 1 year ago
      A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

      community Is topical min a waste of time for diffuse thinners?

      in General  81 upvotes 1 year ago
      The user is considering switching from oral to topical minoxidil due to lack of improvement and side effects, while continuing with dutasteride or finasteride. They seek advice from others with diffuse thinning.

      community Topical latanoprost chance of eye color change?

      in Product  1 upvotes 1 year ago
      The user is using oral minoxidil for hair growth and is considering adding topical latanoprost, but is concerned about potential eye color change. They are seeking advice on the effectiveness of latanoprost for hair thickening and the risk of eye color change.

      community My summation of PP405 - looks promising

      in Research/Science  206 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Reaction to Minoxidil Foam version

      in Minoxidil  1 upvotes 1 year ago
      User experienced itching, redness, and hives from Minoxidil foam and is questioning if they are allergic to Minoxidil or another ingredient. They have switched to oral Finasteride.

      community I was a non-responder to Minoxidil before my esophagus surgery

      in Research/Science  38 upvotes 2 years ago
      The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

      community Questions about dutasteride, minoxidil and nuclear option?

      in Minoxidil  5 upvotes 4 years ago
      The user discussed their experience with hair loss treatments, including finasteride, RU58841, Nizoral, supplements, dermarolling, and minoxidil, which caused significant edema. They also experimented with dutasteride, which led to increased hair loss, and found that Armodafinil reduced minoxidil-related water retention and hair shedding.

      community which is better ; minoxidil with more alcohol or more pg?

      in Minoxidil  4 upvotes 3 years ago
      The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.

      community The end of minoxidil and fin/dut regime

      in Research/Science  106 upvotes 3 months ago
      New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community Wednesday after micro needling through Friday today.

      in Treatment  1 upvotes 1 year ago
      The user is using oral and topical minoxidil, finasteride, dutasteride, and considering adding rosemary and pumpkin saw palmetto to their regimen. They report significant hair growth, especially with dutasteride, and are considering increasing their dose and adding RU58841.

      community What's your thoughts on Pyrilutamide

      in Product  5 upvotes 6 months ago
      The conversation is about using pyrilutamide and RU58841 as topical solutions to prevent hair loss. Pyrilutamide is considered safer but less potent than RU58841, which some users find effective despite potential side effects like heart palpitations.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Min and retinol? Anyone tried it?

      in Research/Science  5 upvotes 2 years ago
      The conversation discusses using minoxidil with retinol for hair loss treatment. Users share their experiences and opinions on the effectiveness of this combination.

      community Broccoli supplement (Sulforaphane) for better Minox results?

      in Minoxidil  4 upvotes 3 years ago
      Broccoli or sulforaphane supplements are unlikely to improve Minoxidil results due to the need for an unrealistically large dose. Tretinoin, micro-needling, and low-dose oral Minoxidil may be more effective for those lacking the necessary enzyme in the scalp.

      community Has anyone tried this Ru58841 from Amazon ?

      in Product  3 upvotes 10 months ago
      RU58841 from Amazon is unreliable, with users reporting no benefits and side effects like eye swelling and chest pain. Rudirect is recommended for purchasing in Europe.