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      community 20M Diffuse Thinning for 2 Years, No Improvement with Treatments

      in General  130 upvotes 6 months ago
      A 20-year-old male is experiencing worsening diffuse thinning despite using topical minoxidil, topical finasteride with minoxidil, oral finasteride, stemoxydine, and pyrilutimide. He is seeking support and advice as he struggles with the mental and physical challenges of hair loss treatments.

      community Shaving is NOT accepting baldness

      in Shaved/buzzed  52 upvotes 3 years ago
      Accepting baldness and the various ways people try to cope with it, such as shaving, using medications like minoxidil and finasteride, or getting a hair transplant. Participants discussed how true acceptance of hair loss involves confronting difficult emotions such as grief for one's former appearance and identity, as opposed to simply superficially hiding it with a shaved head.

      community 10 months progression (plz respond)

      in Is this regrowth?  4 upvotes 1 week ago
      The user is experiencing hair shedding after using minoxidil and is considering switching to dutasteride while planning to increase their oral minoxidil dose. They also use nicotine pouches, Vyvanse, and GHK-Cu, and have noticed thicker eyebrows and lashes from oral minoxidil.

      community Just started DualGen-15 Plus ( w/Finasteride )

      in Finasteride  11 upvotes 7 years ago
      A user discusses their hair loss journey, starting with 5% minoxidil and nizoral, and now using DualGen-15 Plus with 15% minoxidil and 0.1% finasteride. They also use biotin, pumpkin seed oil, Pura D'or Professional shampoo, and derma rolling, noting some shedding and side effects.

      community Roughly 6 month update: I was almost a goner

      in Progress Pictures  48 upvotes 2 years ago
      The user shared a 6-month update on their hair loss treatment, using finasteride/minoxidil gel, ketoconazole shampoo, thickening shampoo and conditioner, and topical minoxidil. They wash their hair three times a week and switched to a less oily topical foam. Other users commented on their hairstyle, advising against it to prevent traction alopecia.

      community Anyone had success with homemade topical Spiro?

      in Female  2 upvotes 9 months ago
      A user is using homemade topical spironolactone for androgenetic alopecia and is unsure about its effectiveness due to concurrent telogen shedding. They are seeking advice on others' experiences with homemade topical spironolactone.

      community No shedding but temples & frontal receeding

      in Finasteride/Dutasteride 6 months ago
      A 24-year-old male started using finasteride and minoxidil for hair loss, noticing reduced hair fall but continued temple and frontal recession. He uses both oral and topical minoxidil, biotin, vitamin D, and coal tar shampoo, and experiences rare heart palpitations.

      community 17 and Balding- Need treatment help and input

      in Chat  6 upvotes 5 years ago
      A 17-year-old in the UK seeks advice on mitigating hair loss until finasteride becomes an option at 19. Recommendations include using Minoxidil and considering other treatments like specific shampoos and dietary changes.

      community Nizoral doesn't seem to be working. Rogaine not suggested by doctor due to cost and poor track record on females. Ideas?

      in Ketoconazole  23 upvotes 7 years ago
      A woman experiencing hair loss and facial hair growth suspects PCOS or androgenic alopecia and is considering treatments like Rogaine, but is concerned about the cost. She has tried various hair care methods and is awaiting a hormone doctor appointment, while others suggest she may have a hormonal imbalance and recommend seeing a gynecologist or trying cheaper versions of Rogaine.

      community I told bro he gotta get on fin asap

      in Satire 3 years ago
      Hair loss treatments, including finasteride and minoxidil, as well as vitamins, supplements, and scalp biopsy. A joke was made about Feline Pattern Baldness in cats.

      community pictures before I started pyrilutamide (repost)

      in Progress Pictures  124 upvotes 3 years ago
      Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.

      community PP405 Might Be the Closest We Have to a Upcoming Cure

      in Technology  237 upvotes 1 year ago
      PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

      community Pyrilutamide: hairloss continues

      in Treatment  12 upvotes 3 years ago
      The conversation is about someone experiencing continued hair loss despite using Pyrilutamide and considering the need for more time or better quality control for the treatment. Another person suggests waiting for the drug to be officially approved due to potential quality issues with current products.

      community Is my hairloss too aggressive to be stopped/reversed ?

      in Chat  4 upvotes 2 years ago
      A 19-year-old male has been experiencing aggressive hair loss since age 15/16 and has tried various treatments including topical Minoxidil, microneedling, tretinoin, retinoic acid, stemoxydine, RU58841, and finasteride without success. He recently added oral Minoxidil but continues to experience significant hair thinning and is considering switching to dutasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 21M. Curly hair. Please read and give your opinion

      in Chat  6 upvotes 1 year ago
      A 21-year-old is experiencing hairline recession and is using finasteride, saw palmetto, gelatin, topical minoxidil with retinoic acid, derma stamping, and scalp massage to address it. Suggestions include adding oral minoxidil, vitamin D3 with K2, and maintaining the current regimen for a year.

      community The first three months on minoxidil 2%

      in Is this regrowth?  1 upvotes 1 year ago
      The user noticed hair thinning and has been using a treatment with minoxidil 2%, hydrocortisone butyrate, and 17 alpha estradiol for three months, seeing some regrowth. The user had dermatitis, now cured, which worsened the hair loss.

      community Galenic lotion. Science behind the components

      in Treatment  1 upvotes 9 months ago
      A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

      community Frustrated this week, shaving an option after a decade of trying

      in Update  59 upvotes 4 months ago
      The user is frustrated with ongoing hair loss despite using treatments like dutasteride, finasteride, and minoxidil, and is considering shaving their head. They are advised to maintain consistency with medication, consider oral minoxidil, and explore hair transplant options.

      community Is it time for my 3-Year Old Nephew to get on Fin & Min? 😓

      in Satire  517 upvotes 3 years ago
      Hair loss in a 3-year-old, with various treatments discussed such as minoxidil, finasteride, dutasteride, RU58841 and biotin supplementation. Some people suggested shaving the head and growing a beard or getting a partial hairpiece instead of attempting to treat it.

      community How dependent will my other hairs get on minoxidil?

      in Minoxidil  12 upvotes 1 year ago
      A user is starting a finasteride and minoxidil routine for diffuse pattern hair loss and is concerned about hair dependency on minoxidil. Responses suggest that new hairs may not survive without minoxidil, but existing hairs won't fall out if minoxidil is stopped, though experiences vary.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 6 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.