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      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 2 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community Where to get raw ingredients for topicals?

      in Product  2 upvotes 11 months ago
      The conversation is about sourcing raw ingredients like finasteride, dutasteride, minoxidil, and tretinoin for making hair loss topicals. A suggestion is made to check Anagen Inc. for these ingredients or contact local suppliers for bulk purchases.

      community Problem with Topican Finasteride, sides

      in General  119 upvotes 4 months ago
      The user experienced side effects like shallow breathing, loss of libido, and erectile issues after using topical finasteride with minoxidil for hair loss. They are considering whether to continue the treatment despite these side effects.

      community How come topical finasteride even works at all?

      in Finasteride/Dutasteride  29 upvotes 5 months ago
      Topical finasteride can effectively reduce scalp DHT by targeting local enzymes, despite less systemic impact compared to oral forms. Combining oral dutasteride with topical finasteride and minoxidil may enhance hair loss prevention, though evidence of its effectiveness is limited.

      community Anyone else a non-responder to spiro?

      in Treatments  63 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.

      community Pp405 - lowkey kinda bad results

      in Treatment  16 upvotes 9 months ago
      PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

      community DHT is higher on DUT than on FIN. Why?

      in Finasteride/Dutasteride  13 upvotes 2 years ago
      The conversation discusses the fluctuation of testosterone levels in men under 40 and the difference between serum DHT and scalp DHT. It also mentions that DHT levels are higher on Dutasteride than on Finasteride, which is unusual.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community How effective is a 7% MNX 0.1% FNS topical?

      in Product  1 upvotes 3 years ago
      A user discusses their rapidly receding hairline and a prescribed topical solution containing 7% Minoxidil, 0.1% Finasteride, and 3% biotinoyl tripeptide. The solution is a custom compound from their dermatologist, costing $50 for a one-month supply.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 4 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community What’s the highest minox % you home brewed ?

      in Minoxidil  2 upvotes 1 year ago
      A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

      community Dry flakes from topical fin use

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user is experiencing white flakes and a greasy look from using a topical solution containing 0.025% finasteride, 8% minoxidil, 0.01% retinoic acid, and 1% hydrocortisone. Suggestions include reducing application frequency, using a brush to clean the scalp, and considering alcohol-free alternatives.

      community Promising new data on peptide serums (not sponsored)

      in Research/Science  7 upvotes 2 months ago
      Combining Minoxidil with peptide serums like Redensyl, Procapil, and Capixyl is more effective for hair growth than using Minoxidil alone, increasing hair density and thickness. However, some users are skeptical about the effectiveness of peptides, suggesting other ingredients or factors might contribute to the results.

      community Oils, Saw Palmetto, Microneedling every 3 days, DHT Shampoo

      in Progress Pictures  300 upvotes 1 year ago
      The user experienced positive hair regrowth using a routine of microneedling every 3 days, applying a blend of castor oil with peppermint and rosemary, bhringraj oil, and moringa oil, and using Pura D'Or DHT-blocking shampoo. They also take multivitamins and saw palmetto daily, reporting no side effects from saw palmetto.

      community Topical finasteride now the safest possible path?

      in Finasteride/Dutasteride  84 upvotes 1 year ago
      Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

      community Rosemary out here changing lives for the better

      in Treatment  90 upvotes 1 year ago
      Rosemary oil is being used as an addition to minoxidil and finasteride for hair health, with mixed opinions on its effectiveness. Some users report positive results, while others see no benefit or experience adverse effects.

      community Pyrilutamide with Alfatradiol and minoxidil (23M)

      in Treatment  2 upvotes 4 months ago
      The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.