The user is experiencing hair shedding while using finasteride and topical minoxidil with tretinoin, keto shampoo, and dermarolling. They hope the shedding indicates future hair regrowth.
A user used dutasteride 0.5mg for 3 months and is unsure about hair regrowth, noting some greying. Responses suggest improvement and that full regrowth may take time with shedding cycles.
Finasteride and Nizoral shampoo with Ketoconazole are used for hair loss treatment. Liquid Chromatography–Mass Spectrometry (LC-MS) is recommended over Enzyme-Linked Immunosorbent Assay (ELISA) for more accurate DHT testing.
The conversation discusses hair regrowth, with the user using finasteride (1 mg), topical minoxidil, and microneedling. A reply suggests the user's hair appears fuller and healthier.
The user reported progress in hair regrowth after three months of using oral finasteride and minoxidil foam, despite initial doubts. They noted no side effects, a clean diet, regular weightlifting, and additional supplements.
Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.
The conversation discusses hair regrowth using oral minoxidil and RU58841, with visible baby hairs appearing after two months. One user questions the choice of RU58841 over finasteride.
A 30-year-old with a family history of receding hairlines is considering starting finasteride due to gradual hairline recession. They are seeking advice on whether to begin treatment or if they are worrying unnecessarily.
Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.
A 22-year-old shared a 3-month update on using oral minoxidil and finasteride for hair loss, showing significant improvement. Users discussed dosages, previous use of topical treatments, and the importance of finasteride.
The user is documenting their hair loss journey, using oral finasteride since January 2025, and plans to add microneedling and rosemary oil. They have experienced no further hair loss but no gains, and are considering oral minoxidil due to having pets.
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.
A 28-year-old underwent three hair transplants totaling 11,102 grafts at Eugenix, using finasteride and minoxidil to manage advanced hair loss. Despite limited density, the results are satisfactory, allowing the individual to feel presentable without a hat.
The user reported hair regrowth progress using minoxidil and dermapen, considering adding finasteride. Others shared experiences with minoxidil, finasteride, and microneedling, recommending finasteride for long-term results but noting potential side effects.
The user has been using oral minoxidil (3mg) and finasteride (1.2mg) for 3 months. Some users notice hair growth, especially at the temples and crown, while others see no difference.
The user has been using Nizoral shampoo, MCT oil with lavender oil, and tea tree conditioner for hair care, considering finasteride if no progress is seen. Some users notice progress in hair thickness and density after three months.
The conversation is about someone's 3-month hair regrowth progress using 5mg oral minoxidil and 0.5mg dutasteride daily, with visible improvement noted.
The conversation discusses using topical dutasteride with a dermapen for hair loss treatment. The user is deciding between liposomal and mesosomal formulations for this purpose.
The user has been using a hair regrowth regimen for 9-10 months, including topical finasteride and minoxidil, various oils, and supplements like multivitamins and omega-3. They observed fine hairs returning and a change in scalp texture after adding cinnamon oil, questioning if this indicates positive hair regrowth.
The user shared their 5-month progress using oral finasteride, topical minoxidil, and weekly dermarolling for hair loss. They expressed pride in their results, receiving positive feedback from others.
Bald men in Mozambique are being targeted due to superstitions that their heads contain gold, leading to dangerous rituals. The conversation humorously discusses this belief and its implications.
A 15-year-old is experiencing uneven hair loss, with one temple receding significantly. They are considering using finasteride, minoxidil, or dutasteride to slow hair loss before visiting a dermatologist, and may consider a hair transplant in the future.
A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.
A user plans to experiment with creating new hair follicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.
The user reports hair regrowth after three months using a daily oral capsule with Minoxidil, Finasteride, and Biotin, derma stamping twice a week, and alternating Nizoral and Mane Root Activator Shampoo, with no side effects except increased nasal hair growth. They observed significant progress on the crown and thickening of the hairline.
A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.
The user has been using 1mg of finasteride for 3.5 months and is questioning if there is hair regrowth. Others suggest it's too early to see significant results and recommend continuing the treatment, with some suggesting adding oral minoxidil for better results.
A 42-year-old user shared positive results from using oral and topical Minoxidil, Finasteride, and weekly dermarolling for hair regrowth over three months. The community responded positively, noting significant progress and discussing treatment details and concerns.
A user is interested in Absci's AI-driven antibody platform, ABS-201, for treating androgenetic alopecia, which shows promising preclinical results and potential for hair regrowth and pigmentation restoration. However, concerns are raised about the drug's development timeline and its advantages compared to existing treatments.