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      community Effects of 2% vs 5% min for sebderm

      in Minoxidil  1 upvotes 2 years ago
      Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

      community 3 months progress on fin and min + micro needling (19m)

      in Progress Pictures  762 upvotes 2 years ago
      A 19-year-old male shared his 3-month hair regrowth progress using finasteride, minoxidil, and microneedling, with noticeable improvement. He uses 1mg oral finasteride daily, 5% minoxidil foam twice a day after day 80, and microneedles with a 1.5mm derma stamp every 1-2 weeks.

      community M20 on Fin+Min for 1 Year – Crown Still Thin, Should I Add Dut/Oral Min?

      in Progress Pictures  26 upvotes 9 months ago
      A 20-year-old has been using finasteride and topical minoxidil for a year but is considering adding oral minoxidil, dutasteride, and biotin due to unsatisfactory results. Opinions vary, with some suggesting patience and others recommending different treatments, but caution is advised against using multiple oral drugs due to potential side effects.

      community Long term take(15-20y) 2.5mg oral minoxidil safe?

      in Minoxidil  55 upvotes 9 months ago
      An 18-year-old is considering taking 2.5mg oral minoxidil for 15-20 years alongside dutasteride and finasteride. They are concerned about the long-term safety and effectiveness of minoxidil in maintaining hair stability.

      community Serious Oral Minoxidil Side Effects

      in Minoxidil  30 upvotes 4 years ago
      A user experienced severe side effects, including heart-related symptoms, after increasing their oral minoxidil dosage to 5 mg, leading them to stop the medication and seek medical advice. Many users advised against high doses of oral minoxidil, suggesting anxiety as a possible cause, and recommended consulting a doctor or switching to topical treatments.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 4 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 8 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Anybody here cooking oral minoxidil?

      in Minoxidil  25 upvotes 7 months ago
      The conversation is about making oral minoxidil pills for personal use, including inquiries about ingredients and binders. The user mentions taking 2.5mg of oral minoxidil daily.

      community Losing ground after over 5 years on dutasteride and min

      in Minoxidil  1 upvotes 10 months ago
      The user is experiencing diffuse hair thinning despite using dutasteride and minoxidil for over five years and is considering adding oral minoxidil, microneedling, and nizoral to their regimen. They are concerned about the effectiveness and side effects of these treatments, especially with an upcoming event.

      community 4 months result topical min 5% Nw6

      in Progress Pictures  14 upvotes 1 year ago
      The user experienced good hair growth using topical minoxidil 5% and finasteride for 4 months but lost progress after switching to oral minoxidil and finasteride and shaving their head. They have returned to using topical treatments and are seeking advice on similar experiences.

      community 2 months in of Minoxidil 5% and finasteride 0.1%

      in Progress Pictures  1122 upvotes 1 year ago
      A 26-year-old is using minoxidil 5% and finasteride 0.1% topically for hair growth, with noticeable improvement in two months, especially on the hairline. They also use a derma-stamp every 15 days and report minimal side effects.

      community Anagenic is trying to compound Gt20029

      in Treatment  56 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community 19 years old - 3 months of min+fin

      in Progress Pictures  96 upvotes 4 months ago
      A 19-year-old has been using a regimen of 5% topical minoxidil and 1mg oral finasteride for three months to combat early-onset balding. The user reports some progress and plans to continue the current treatment, while others suggest considering additional treatments like dutasteride for more aggressive cases.

      community 4 years progress- Minox combined with Fin

      in Progress Pictures  198 upvotes 11 months ago
      A user shared their 4-year progress using topical minoxidil and 1mg finasteride daily for hair regrowth, noting plans to reduce finasteride due to minor side effects. They emphasized consistency as key to success, with noticeable improvements in hair density and color.

      community Is oral + topical minoxidil too much?

      in General  102 upvotes 1 year ago
      The user is considering a hair transplant and is using Kirkland 5% foam minoxidil, oral finasteride, oral minoxidil, and topical minoxidil 7% spray. They are concerned about the necessity and potential side effects of oral minoxidil before the transplant.

      community 52M completed my first 30 day on 5% topical Minoxidil

      in Progress Pictures  37 upvotes 2 years ago
      A 52-year-old man has been using 5% Minoxidil twice daily for 30 days to treat hair loss, alongside 2.5mg Finasteride, which he reduced from 5mg despite his doctor's advice. He has a history of hair loss due to testosterone treatment and hopes to see improvement in the crown area of his scalp.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 4 months oral min + fin, derma rolling

      in Progress Pictures  31 upvotes 2 years ago
      A user shared their 4-month progress using oral minoxidil, finasteride, and derma rolling for hair loss. They reported positive results and expressed gratitude for the treatment.

      community 1 month topical min 5% + derma stamp progress

      in Progress Pictures  1 upvotes 9 months ago
      A user noticed hair loss since age 16 and is now using minoxidil 5% twice daily, scalp massages, and a derma stamp weekly, along with Alpecin Caffeine Shampoo. They report seeing new hair growth and are happy with the progress.

      community 3 months update (oral fin/min 1.2/3mg)

      in Progress Pictures  10 upvotes 5 months ago
      The user started using finasteride and minoxidil in October 2025 and noticed hair growth and thickening after three months, despite initial concerns about side effects. They are hopeful for continued progress and grateful for the support from the forum community.

      community 3 month progress pictures RU fin and OM

      in Progress Pictures  42 upvotes 2 years ago
      The user shared progress pictures after three months of using RU58841, finasteride, and OM (oxidative stress modulators) for hair loss treatment. They haven't noticed much change but are seeking feedback on their results.

      community Survived First Monte. Shedding is real

      in Progress Pictures  370 upvotes 2 years ago
      The user is treating hair loss with 1mg finasteride every other day, daily topical minoxidil, and weekly derma rolling, and is considering using hair fibers for special occasions. There is a discussion about the initial shedding phase of minoxidil treatment and the importance of consistent photo conditions to track progress.