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      community The pessimism about the Crisp Cas 9 is excessive

      in Chat  12 upvotes 7 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community Binding affinity of pyrilutamide!

      in Update  172 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community I wish pp405 work and i have full head of hair in 2028-2030

      in Chat  106 upvotes 6 months ago
      People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.

      community About microneedling for hair.For AGA,Is dermastamp better?

      in Microneedling  7 upvotes 10 months ago
      A 22-year-old female with AGA due to PCOS is using 5% minoxidil foam and 2mg finasteride daily, and is seeking advice on microneedling frequency and safety. Concerns about finasteride dosage and its effects on PCOS were discussed, with emphasis on trusting the prescribed treatment plan.

      community New cure? A new combo to dream with hair regeneration

      in Research/Science  33 upvotes 11 months ago
      A stem cell and adenosine triphosphate cocktail showed promising results in hair regrowth for male and female mice, with potential for future clinical trials. Users humorously reacted to the success in mice, expressing hope for human application.

      community Dr. Rassman vs Kevin Mann on Eucapil

      in Treatment  4 upvotes 5 years ago
      Eucapil is discussed as a potential hair loss treatment with some believing it to be effective, though its efficacy compared to finasteride is debated. It is considered an anti-androgen treatment, often used alongside other treatments like minoxidil and finasteride, but lacks independent studies to fully support its effectiveness.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  330 upvotes 10 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community I hope ET-02 or PP405 will be released in the next 4-5 years

      in Product  15 upvotes 11 months ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community Pyrilutamide isn’t failed at all.

      in Technology  11 upvotes 1 year ago
      Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

      community CB-03-01 / Breezula Personal Results

      in Treatment  16 upvotes 3 months ago
      The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

      community Positive Hair Result in Patient using Tirzepatide

      in Research/Science  5 upvotes 1 year ago
      A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.

      community I (diffuse thinner) would genuinely prefer having the Generic MPB hairloss

      in Chat  35 upvotes 1 year ago
      The conversation discusses struggles with diffuse thinning and hair loss treatments, including the use of dutasteride, minoxidil, and finasteride, with limited success. The original poster regrets having a hair transplant at 21 due to weak donor hair and ongoing thinning.

      community Can we get a reality check on PP405?

      in Research/Science  80 upvotes 6 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community Looks like I’m allergic to propylene glycol..

      in Minoxidil  4 upvotes 4 years ago
      The user is experiencing an allergic reaction to propylene glycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.

      community TrichoGene minoxidil response test?

      in Minoxidil 2 years ago
      The conversation is about the legitimacy and affordability of ordering a Minoxidil response test from TrichoGene, an India-based company, as an alternative to Daniel Alain. The user is seeking feedback on whether TrichoGene is a reliable option.

      community Pyrilutamide (KX-826) vs CB-03-01 which one do you think is better?

      in Product  8 upvotes 3 years ago
      The conversation is about comparing hair loss treatments Pyrilutamide (KX-826) and CB-03-01, discussing their cost, side effects, and effectiveness. The user questions whether to try CB-03-01, which is more expensive and potentially less effective, or switch to the cheaper and possibly better Pyrilutamide.

      community if hmi-115 truly works, we can just get off off fin?

      in Chat  19 upvotes 3 years ago
      A potential new hair loss treatment, HMI-115, and the possibility of discontinuing finasteride in favor of it. The conversation also includes discussion about other benefits of using finasteride.