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      community M46 - 3 week progress on HIMS serum

      in Progress Pictures  12 upvotes 2 years ago
      A 46-year-old male shared his 3-week progress using HIMS serum with Finasteride 0.3% and Minoxidil 6%, showing improvement without noticeable shedding. His routine includes vitamins, a healthy diet, and specific hair care practices like microneedling and using caffeine solution.

      community hairloss treatment, what to expect (bloodwork)

      in Treatment  1 upvotes 8 months ago
      The conversation discusses hair loss treatment options, focusing on finasteride and its potential effects on gynecomastia. The user is considering finasteride while managing hormone levels with supplements like boron, vitamin D, zinc, magnesium, and P5P, and is advised to consult an endocrinologist for further evaluation.

      community Natural remedies in conjunction with fin?

      in Chat  5 upvotes 5 years ago
      The user has been on finasteride for 16 months and is considering natural remedies like peppermint oil, rosemary oil, saw palmetto, green tea extract, l-lysine, and oral castor oil to enhance hair growth in addition to finasteride. They are interested in the potential benefits of combining these natural treatments with finasteride to improve hair loss outcomes.

      community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

      in Treatment  4 upvotes 1 year ago
      The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

      community 2.5% topical fin too high?

      in General  53 upvotes 1 year ago
      The conversation discusses starting topical finasteride for hair loss, with concerns about high dosages. It suggests starting with a lower concentration, like 0.1% or 0.3%, especially with liposomal versions.

      community Almost 4 months of oral fin, topical min and microneedling

      in Progress Pictures  752 upvotes 2 years ago
      User "Mostuls" shared their 4-month hair loss treatment routine, which includes daily oral finasteride, twice-daily topical minoxidil, and microneedling twice a week with no side effects. Other users discussed the specifics of the treatment and expressed positive reactions to the results.

      community Progress with 7 months of treatment

      in Progress Pictures  82 upvotes 8 months ago
      The user shared progress after 7 months of hair loss treatment using topical minoxidil with finasteride, oral minoxidil, microneedling, LLLT laser cap, and scalp massage. They reported thicker, denser hair with no significant side effects.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community What to take from the Actifolic?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user is considering starting Minoxidil and is looking for a topical solution to combine with it. They are confused about which product to prioritize among options like RU58841, Pyrilutamide, FinaTopic, and DutaTopic.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 5 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Oral min 2.5mg closing in on 3 months

      in Progress Pictures  372 upvotes 3 years ago
      _the_orange_box_'s experience using oral minoxidil, with discussion about finasteride and the potential side effects of both treatments. Other users shared their own experiences related to hair loss treatments.

      community Castor Oil and Pumpkin Seed Oil

       6 upvotes 9 years ago
      The conversation discusses the use of castor oil and pumpkin seed oil for hair thickness and shine, with concerns about oral consumption. The user is already using Minoxidil, finasteride, and RU58841.

      community Self-Experiment - Topical Rapamycin or a-KB

      in Treatment  4 upvotes 4 years ago
      A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

      community What are everyone's expectations for PP405?

      in Chat  10 upvotes 1 month ago
      PP405 is expected to be a promising addition to hair loss treatments, potentially working well with existing treatments like finasteride and minoxidil, but not as a standalone solution. Users are hopeful for its effectiveness, especially in combination with other treatments, though expectations vary.

      community Oral minoxidil vs massive dosage of topical absorption rate

      in Minoxidil  3 upvotes 4 years ago
      Oral minoxidil is generally more effective than topical minoxidil, despite higher side effect risks. Topical minoxidil can achieve higher bloodstream levels in some individuals, but effectiveness depends on conversion and scalp response.

      community Dr. Bloxham Final verteporfin update

      in Research/Science  59 upvotes 1 year ago
      Verteporfin is being explored for its potential to improve hair transplant outcomes by reducing scarring and increasing donor hair follicles. There is skepticism about the results, with some claiming misleading presentation of evidence.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 3 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community 3 months progress topical min/fin (19M)

      in Progress Pictures  96 upvotes 1 year ago
      A 19-year-old is using topical minoxidil 7% and finasteride 0.1% foam, along with a laser cap, to combat hair loss. They report progress despite initial shedding and are considering switching to oral finasteride in the future for convenience.

      community PP405 Hairloss Reversal and Hairline Restoration

      in Treatment  5 upvotes 4 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community 1 year in to my journey with oral min & fin

      in Progress Pictures  169 upvotes 7 months ago
      The user experienced positive results using oral minoxidil and finasteride chewables for hair loss, with no significant side effects. They noted new hair growth and shared their routine, which includes diet changes and weightlifting.

      community My eyelashes and eyebrows on oral min

      in Progress Pictures  302 upvotes 3 years ago
      User Crazy-Signature930 shares progress on oral minoxidil for eyelashes and eyebrows. Others comment on the impressive results and ask about side effects and duration of use.